Browsing by Author "Verdugo Salgado, Ricardo Alejandro"

Now showing items 1-4 of 4

    • Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, ... 
      Kehdy, Fernanda S. G.; Pita Oliveira, Murilo; Scudeler, Mariana M.; Torres Loureiro, Sabrina; Zolini, Camila; Moreira, Rennan; Michelin, Lucas A.; Alvim, Isabela; Silva Carvalho, Carolina; Furlan, Vinicius C.; Aquino, María M.; Santolalla, Meddly L.; Borda, Víctor; Soares Souza, Giordano B.; Jaramillo Valverde, Luis; Vásquez Domínguez, Andrés; Sánchez Neira, César; Aguiar, Renato S.; Verdugo Salgado, Ricardo Alejandro; Connor, Timothy D. O.; Guio, Heinner; Tarazona Santos, Eduardo; Leal, Thiago P.; Rodrigues Soares, Fernanda (Soc Brasil Genética, 2021)
      For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the ...
    • Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps 
      Adeyemo, Adebowale; Balaconis, Mary K.; Darnes, Deanna R.; Fatumo, Segun; Granados Moreno, Palmira; Hodonsky, Chani J.; Inouye, Michael; Kanai, Masahiro; Kato, Kazuto; Knoppers, Bartha M.; Lewis, Anna C. F.; Martin, Alicia R.; McCarthy, Mark I.; Meyer, Michelle N.; Okada, Yukinori; Richards, J. Brent; Richter, Lucas; Ripatti, Samuli; Rotimi, Charles N.; Sanderson, Saskia C.; Sturm, Amy C.; Verdugo Salgado, Ricardo Alejandro; Widen, Elisabeth; Willer, Cristen J.; Wojcik, Genevieve L.; Zhou, Alicia (Nature Research, 2021)
      Polygenic risk scores (PRSs) aggregate the many small effects of alleles across the human genome to estimate the risk of a disease or disease-related trait for an individual. The potential benefits of PRSs include ...
    • The Association between fasting glucose and sugar sweetened beverages intake is greater in latin americans ... 
      López-Portillo García, María de Lourdes; Huidobro, Andrea; Tobar Calfucoy, Eduardo Andrés; Yañez, Cristián; Retamales Ortega, Rocío Mariana; Garrido Tapia, Macarena; Acevedo, Johanna; Paredes, Fabio; Cid Ossandón, Vicente; Ferreccio, Catterina; Verdugo Salgado, Ricardo Alejandro (MDPI, 2022)
      Chile is one of the largest consumers of sugar-sweetened beverages (SSB) world-wide. However, it is unknown whether the effects from this highly industrialized food will mimic those reported in industrialized countries or ...
    • Validation of an NGS panel designed for detection of actionable mutations in tumors common in latin america 
      Salvo, Mauricio; González Feliu, Evelin; Toro, Jéssica; Gallegos Méndez, Iván; Maureira Caviedes, Ignacio Andrés; Miranda González, Nicolás; Barajas Barajas, Olga Beatriz; Bustamante, Eva; Ahumada Olea, Mónica Beatriz; Colombo Flores, Alicia Angelina; Armisen, Ricardo; Villaman, Camilo; Ibáñez, Carolina; Bravo, María Loreto; Sanhueza, Verónica; Spencer, M. Loreto; Toro, Gonzalo de; Morales, Erik; Bizama, Carolina; García, Patricia; Carrasco, Ana María; Gutiérrez Cordero, Lorena; Bermejo, Justo; Verdugo Salgado, Ricardo Alejandro; Marcelain Cubillos, Katherine Jenny (MDPI, 2021)
      Next-generation sequencing (NGS) is progressively being used in clinical practice. However, several barriers preclude using this technology for precision oncology in most Latin American countries. To overcome some of these ...