Browsing by Author "Vidal, René"

Now showing items 1-3 of 3

    • ER proteostasis disturbances in Parkinson’s disease: novel insights 
      Mercado, Gabriela; Castillo Jorquera, Valentina Andrea; Vidal, René; Hetz Flores, Claudio Andrés (Frontiers Media, 2015)
    • Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis 
      Nassif, Melissa; Valenzuela, Vicente; Rojas Rivera, Diego; Vidal, René; Matus, Soledad; Castillo, Karen; Fuentealba, Yerko; Kroemer, Guido; Levine, Beth; Hetz Flores, Claudio (Taylor and Francis Inc., 2014)
      Pharmacological activation of autophagy is becoming an attractive strategy to induce the selective degradation of aggregate-prone proteins. Recent evidence also suggests that autophagy impairment may underlie the pathogenesis ...
    • Targeting the unfolded protein response for disease intervention 
      Rivas, Alexis; Vidal, René; Hetz Flores, Claudio (Taylor & Francis, 2015)
      Introduction: The accumulation of misfolded proteins in the endoplasmic reticulum (ER) generates a stress condition that engages the unfolded protein response (UPR). The UPR is an adaptive reaction that aims to reestablish ...