PGE(2) is involved in a wide variety of physiological and pathological processes; however, deciphering its role in early Mammalian development has been difficult due to the maternal contribution of PGE(2). To overcome this ...

The sensory organs of the zebrafish lateral-line system (neuromasts) originate from migrating primordia that move along precise pathways. The posterior primordium, which deposits the neuromasts on the body and tail of the ...

Background: Development of the posterior lateral line (PLL) system in zebrafish involves cell migration, proliferation and differentiation of mechanosensory cells. The PLL forms when cranial placodal cells delaminate ...