Browsing by Author "Yellon, Derek M."

Now showing items 1-3 of 3

    • Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent ... 
      Riquelme, Jaime; Westermeier, Francisco; Hall, Andrew R.; Vicencio, Jose; Pedrozo Cibils, Zully; Ibacache, Mauricio; Fuenzalida, Barbara; Sobrevia, Luis; Davidson, Sean M.; Yellon, Derek M.; Sánchez, Gina; Lavandero González, Sergio (Elsevier, 2016)
      The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can also act as a preconditioning mimetic. The ...
    • Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated ... 
      Kalkhoran, Siavash Beikoghli; Kriston-Vizi, Janos; Hernández Resendiz, Sauri; Crespo Avilan, Gustavo E.; Rosdah, Ayeshah A.; Lees, Jarmon G.; Simoes Da Costa, Joanna Rodrigues; Ling, Naomi X. Y.; Holien, Jessica K.; Samangouei, Parisa; Chinda, Kroekkiat; Yap, En Ping; Riquelme Meléndez, Jaime Andrés; Ketteler, Robin; Yellon, Derek M.; Lim, Shiang Y.; Hausenloy, Dereck J. (Oxford University Press, 2022)
      Aims Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct size. The clinically used anti-hypertensive ...
    • Plasma Exosomes Protect the Myocardium From Ischemia-Reperfusion Injury 
      Vicencio, José M.; Yellon, Derek M.; Sivaraman, Vivek; Das, Debashish; Boi-Doku, Claire; Arjun, Sapna; Zheng, Ying; Riquelme, Jaime A.; Kearney, Jessica; Sharma, Vikram; Multhoff, Gabriele; Hall, Andrew R.; Davidson, Sean M. (Elsevier, 2015)
      BACKGROUND Exosomes are nanometer-sized vesicles released from cells into the blood, where they can transmit signals throughout the body. Shown to act on the heart, exosomes’ composition and the signaling pathways they ...