Browsing by Subject "β-Catenin"
Now showing items 1-5 of 5
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(2011)β-Catenin is crucial in the canonical Wnt signaling pathway. This pathway is up-regulated by CK2 which is associated with an enhanced expression of the antiapoptotic protein survivin, although the underlying molecular ...
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(Medicina Oral, 2021)Background: Oral cancer represents the sixth most common cancer in the world and is associated with 40-50% survival at 5 years. Within oral malignancies, oral squamous cell carcinoma (OSCC) is commonly preceded by potentially ...
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(Elsevier, 2019)Objectives: To evaluate the localization of β-catenin in oral dysplastic cells, the expression of target genes upregulated in oral dysplasia, and the role of Wnt ligands in these events. Materials and methods: Subcellular ...
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(Elsevier, 2015)The key protein in the canonicalWnt pathway is β-catenin, which is phosphorylated both in absence and presence ofWnt signals by different kinases. Upon activation in the cytoplasm, β-catenin can enter into the nucleus ...
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(Academic Press Inc., 2019)Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. A 20% of familial ALS cases are associated with mutations in the gene coding for superoxide dismutase 1 (SOD1). The ...