Browsing by Subject "Atherosclerosis"

Now showing items 1-14 of 14

    • Association between atherosclerosis and periodontitis Aterosclerosis en sujetos con periodontitis 
      López, Néstor J.; Chamorro, Adriana; Llancaqueo, Marcelo (2011)
      Chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. Aim: To evaluate the association between periodontitis and early atherosclerosis. Material and ...
    • Autophagy mediates tumor necrosis factor-alpha-induced phenotype switching in vascular smooth muscle A7r5 cell line 
      García Miguel, Marina; Riquelme, Jaime A.; Norambuena Soto, Ignacio; Morales, Pablo E.; Sanhueza Olivares, Fernanda; Núñez Soto, Constanza Belén; Mondaca Ruff, David; Cancino Arenas, Nicole; San Martín, Alejandra; Chiong Lay, Mario (Public library science, 2018)
      Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a chronic inflammatory component with high levels of tumor necrosis ...
    • Cardiovascular autophagy concepts, controversies, and perspectives 
      Lavandero González, Sergio; Troncoso Cotal, Rodrigo; Rotherme, Beverly; Martinet, Wim; Sadoshima, Junichi; Hill, Joseph (Taylor and Francis Inc., 2013)
      Despite recent scientific and technological advances, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient response to cellular stress, has been ...
    • Clinical pharmacology and therapeutic use of antioxidant vitamins 
      Rodrigo Salinas, Ramón; Guichard, Cristián; Charles, Roberto (2007)
      The clinical use of antioxidants has gained considerable interest during the last decade. It was suggested from epidemiological studies that diets high in fruits and vegetables might help decrease the risk of cardiovascular ...
    • Helicobacter pylori: A new cardiovascuar risk factor? 
      Martínez Torres, Alejandra; Martínez Gaensly, Miguel (2002)
      There is increasing evidence that certain microbial agents may have an etiopathogenic role in the development of atherothrombosis. Helicobacter pylori, a bacterium that causes peptic ulcer disease, has been suggested as ...
    • Incremental replacement of saturated fats by n 3 fatty acids in high-fat, high-cholesterol diets reduces ... 
      Chang, Chuchun L.; Torrejón, Claudia; Jung, Un Ju; Graf, Kristin; Deckelbaum, Richard J. (Elsevier, 2014)
      Objective: Effects of progressive substitution of dietary n 3 fatty acids (FA) for saturated FA (SAT) on modulating risk factors for atherosclerosis have not been fully defined. Our previous reports demonstrate that SAT ...
    • Incremental replacement of saturated fats by n-3 fatty acids in high-fat, high-cholesterol diets reduces ... 
      Chang, Chuchun L.; Torrejon, Claudia; Jung, Un Ju; Graf, Kristin; Deckelbaum, Richard J. (Elsevier Ireland Ltd, 2014)
      Objective: Effects of progressive substitution of dietary n-3 fatty acids (FA) for saturated FA (SAT) on modulating risk factors for atherosclerosis have not been fully defined. Our previous reports demonstrate that SAT ...
    • Molecular mechanisms of autophagy in the cardiovascular system 
      Gatica, Damián; Chiong Lay, Mario; Lavandero González, Sergio; Klionsky, Daniel J. (Lippincott Williams and Wilkins, 2015)
      Autophagy is a catabolic recycling pathway triggered by various intra- or extracellular stimuli that is conserved from yeast to mammals. During autophagy diverse cytosolic constituents are enveloped by double-membrane ...
    • Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward ... 
      Bejarano, Julian; Navarro Márquez, Mario F.; Morales Zavala, Francisco; Morales, Javier O.; García Carvajal, Ivonne; Araya Fuentes, Eyleen; Flores, Yvo; Verdejo, Hugo E.; Castro, Pablo F.; Lavandero González, Sergio; Kogan Bocian, Marcelo (Ivyspring International Publisher, 2018)
      © Ivyspring International Publisher. Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying ...
    • Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases 
      Morales Montecinos, Javier; Sepúlveda Rivas, Sabrina; Oyarzún Ampuero, Felipe; Lavandero González, Sergio; Kogan Bocian, Marcelo (Bentham, 2015)
      Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of ...
    • Oxidative stress in the local and systemic events of apical periodontitis 
      Hernández Ríos, Patricia; Pussinen, Pirkko J.; Vernal Astudillo, Rolando; Hernández, Marcela (Frontiers Media SA, 2017)
      Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to ...
    • Regulation of the sodium-phosphate cotransporter Pit-1 and its role in vascular calcification 
      González, Magdalena; Martínez, Rafael; Amador, Cristián; Michea Acevedo, Luis (2009)
      Vascular calcification is caused by the deposition of basic calcium phosphate crystals in blood vessels, myocardium, and/or cardiac valves. Calcification decreases artery wall compliance, and arterial calcification is ...
    • SASH1, a new potential link between smoking and atherosclerosis 
      Weidmann, Henri; Touat-Hamici, Zahia; Durand, Hervé; Mueller, Christian; Chardonnet, Solenne; Pionneau, Cedric; Charlotte, Frédéric; Janssen, Klaus-Peter; Verdugo, Ricardo; Cambien, Francois; Blankenberg, Stefan; Tiret, Laurence; Zeller, Tanja; Ninio, Ewa (Elsevier, 2015)
      Objective: We have previously reported that SASH1 expression is increased in circulating human monocytes from smokers and was positively correlated with the number of carotid atherosclerotic plaques. The aim of this study ...
    • The role of endothelial lipase in atherogenesis Lipasa endotelial y su relación con la enfermedad cardiovascular ... 
      Camila Pierart, Z.; Valentina Serrano, L. (2012)
      Endothelial lipase (EL) is synthetized by endothelial cells and its main substrates are lipoprotein phospholipids. Over expression of EL reduces high density lipoprotein (HDL) cholesterol and phospholipids, in vivo and in ...