Now showing items 1-14 of 14

    • McDonald, Tanya S.; Carrasco Pozo, Catalina; Hodson, Mark P.; Borges, Karin (Soc Neuroscience, 2017)
      Temporal lobe epilepsy is a common form of adult epilepsy and shows high resistance to treatment. Increasing evidence has suggested that metabolic dysfunction contributes to the development of seizures, with previous studies ...
    • Martínez Moya, Pilar; Campusano, Sebastián; Córdova Vargas, Pamela; Paradela, Alberto; Sepúlveda Lillo, Dionisia; Alcaíno Gorman, Jennifer; Baeza Cancino, Marcelo; Cifuentes Guzmán, Víctor (American Society for Microbiology, 2020)
      Xanthophyllomyces dendrorhous is a carotenogenic yeast with a singular metabolic capacity to produce astaxanthin, a valuable antioxidant pigment. This yeast can assimilate several carbon sources and sustain fermentation ...
    • Leijenaar, Jolien F.; Dorhout Mees, Sanne M.; Algra, Ale; van den Bergh, Walter M.; Rinkel, Gabriel J.E.; Dorhout Mees, S. M.; van den Bergh, W. M.; Rinkel, G. J.E.; Algra, A.; van Buuren, M.; Al-Shahi Salman, R.; Boiten, J.; van Kooten, F.; Kuijsten, H.; Lavados Germain, Pablo Manuel (Blackwell Publishing Ltd, 2015)
      © 2015 World Stroke Organization. Background: Magnesium treatment did not improve outcome in patients with aneurysmal subarachnoid haemorrhage in the Magnesium in Aneurysmal Subarachnoid Haemorrhage II trial. We hypothesized ...
    • Buchanan, Victoria L.; Wang, Yujie; Blanco, Estela; Graff, Mariaelisa; Albala Brevis, Cecilia; Burrows Argote, Raquel; Santos, José L.; Ángel, Barbara; Lozoff, Betsy; Voruganti, Venkata Saroja; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der Ida; Yao, Jie; Tan, Jingyi; Downie, Carolina; Highland, Heather M.; Justice, Anne E.; Gahagan, Sheila; North, Kari E. (Wiley, 2020)
      Background The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latino (H/L) populations in comparison to adults and populations of European ancestry. Objective To identify genetic ...
    • Sepúlveda Quiñenao, Claudia Patricia; Rodríguez Silva, José Manuel; Díaz Castro, Francisco; Campo, Andrea del; Bravo Sagua, Roberto Francisco; Troncoso Cotal, Rodrigo Hernán (MDPI, 2022)
      Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GR alpha and GR beta. ...
    • Pierart, C.; Serrano, V.; Rubio, L.; Ebensperger, R.; Foncea, R. (2011)
      Introduction: Endothelial Lipase (EL), enzyme thatmodulates HDL metabolism, is overregulated by inflammatory-cytokines. Type 2 Diabetes (DM2) has been associatedwith a subclinical inflammation, so it has beenruled that ...
    • Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)
      Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
    • Bunout Barnett, Daniel; Petermann, Margarita; Bravo, Roberto; Kelly,; Hirsch Birn, Sandra; Ugarte,; Ilurriaga, (1989)
      Glucose intolerance is frequently found in alcoholic patients and an impaired insulin response has been documented in them. To look for alternative mechanisms that could explain this intolerance, a glucose turnover using ...
    • Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)
      Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
    • Rajendran, Saravanan; Manoj, Devaraj; Raju, Kumar; Dionysiou, Dionysios D.; Naushad, Mu; Gracia Caroca, Francisco; Cornejo, Lorena; Gracia Pinilla, M. A.; Ahamad, Tansir (Elsevie, 2018)
      An extraordinary sensitive and selective non-enzymatic glucose sensor has been demonstrated based on the electrochemically highly stable NiO-TiO2 mixed oxide comprising the defect induced mesoporous TiO2 nanoparticles with ...
    • Pedreschi, Franco; Kaack, Karl; Granby, Kit (2004)
      Reduction of acrylamide formation in potato chips was investigated in relation to frying temperature and three treatments before frying. Potato slices (Tivoli variety, diameter: 37 mm, width: 2.2 mm) were fried at 150°C, ...
    • Martínez Moya, Pilar; Campusano, Sebastián; Sepúlveda, Dionisia; Paradela Elizalde, Alberto; Alcaíno Gorman, Jennifer Cecilia; Baeza Cancino, Marcelo Enrique; Cifuentes, Víctor (MDPI, 2022)
      Xanthophyllomyces dendrorhous is a natural source of astaxanthin and mycosporines. This yeast has been isolated from high and cold mountainous regions around the world, and the production of these secondary metabolites ...
    • Cataldo, L. R.; Mizgier, María Luisa; Busso, Dolores; Olmos, P.; Galgani Fuentes, José; Valenzuela Báez, Rodrigo; Mezzano, Diego; Aranda, E.; Cortés, V. A.; Santos M., José Luis (Hindawi Publishing Corporation, 2016)
      High circulating nonesterified fatty acids (NEFAs) concentration, often reported in diabetes, leads to impaired glucose-stimulated insulin secretion (GSIS) through not yet well-defined mechanisms. Serotonin and dopamine ...
    • Quiroz, Natalia; Rivas, Nicole; Pozo, Talía del; Burkhead, Jason; Suazo Romo, Miriam; González, Mauricio; Latorre, Mauricio (Springer, 2015)
      Copper is an essential micronutrient for organism health. Dietary changes or pathologies linked to this metal induce changes in intracellular glutathione concentrations. Here, we studied the transcriptional activation of ...