Now showing items 1-6 of 6

    • Madsen, Agnete R.; Knudsen, Jonas R.; Henríquez Olguín, Carlos; Angin, Yeliz; Zaal, Kristien J.; Sylow, Lykke; Schjerling, Peter; Ralston, Evelyn; Jensen, Thomas E. (American Physiological Society, 2018)
      Studies in skeletal muscle cell cultures suggest that the cortical actin cytoskeleton is a major requirement for insulin-stimulated glucose transport, implicating the beta-actin isoform, which in many cell types is the ...
    • Pérez, Alejandra; Ojeda, Paola; Valenzuela, Ximena; Ortega, Marcela; Sánchez, Claudio; Ojeda, Lorena; Castro, Maite; Cárcamo, Juan G.; Rauch, M. Cecilia; Concha, Ilona I.; Rivas, Coralia I.; Vera, Juan C.; Reyes, Alejandro M. (2009)
      Gossypol is a natural disesquiterpene that blocks the activity of the mammalian facilitative hexose transporter GLUT1. In human HL-60 cells, which express GLUT1, Chinese hamster ovary cells overexpressing GLUT1, and human ...
    • Villar, Pablo; Delgado Arriagada, Ricardo; Vergara Montecinos, Cecilia; Reyes, Juan G.; Bacigalupo Vicuña, Juan (Soc Neuroscience, 2017-06-07)
      The mechanisms that power the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance for the functions of these important and ubicuous organelles. The olfactory epithelium is mostly ...
    • Paredes Díaz, Paula Andrea; Dimasuay, Kris Genelyn; Koele Schmidt, Lindsey; Jang, Brian; Barbour, Linda A.; Jansson, Thomas; Powell, Theresa L. (Elsevier, 2017)
      Use of glyburide in gestational diabetes (GDM) has raised concerns about fetal and neonatal side effects, including increased birth weight. Placental nutrient transport is a key determinant of fetal growth, however the ...
    • Jorquera, Gonzalo; Russell, Javier; Monsalves Álvarez, Matías; Cruz, Gonzalo; Valladares-Ide, Denisse; Basualto Alarcón, Carla Edith; Barrientos, Genaro; Estrada, Manuel; Llanos, Paola (MDPI, 2021)
      Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin ...
    • Troncoso Magñin, Mayarling Francisca; Pavez Giani, Mario Gustavo; Wilson Rodríguez, Carlos Antonio; Lagos Cerón, Daniel Alejandro; Durán Gárate, Javier Andre; Ramos, Sebastián; Barrientos Briones, Genaro Christian; Silva, Patricio; Llanos Vidal, Paola Andrea; Basualto Alarcón, Carla Edith; Westenbrink, B. Daan; Lavandero González, Sergio Alejandro; Estrada Hormazábal, Manuel Iván (BMC, 2021)
      Background Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that ...