Browsing by Subject "High-fat diet"

Now showing items 1-8 of 8

    • Central ceramide signaling mediates obesity-induced precocious puberty 
      Heras, Violeta; Castellano, Juan Manuel; Fernandois, Daniela; Velasco, Inmaculada; Rodríguez Vázquez, Elvira; Roa, Juan; Vázquez, María Jesús; Ruiz Pino, Francisco; Rubio, Matías; Pineda, Rafael; Torres, Encarnación; Avendaño, María Soledad; Paredes Vargas, Alfonso; Pinilla, Leonor; Belsham, Denise; Dieguez, Carlos; Gaytan, Francisco; Casals, Nuria; López, Miguel; Tena Sempere, Manuel (Cell, 2020)
      Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked to higher disease burden later in life. The mechanisms underlying this association remain elusive. Here we show that brain ...
    • N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation ... 
      Tapia Opazo, Gladys; Valenzuela Báez, Rodrigo; Espinosa Escalona, Berta; Romanque Ulloa, Pamela; Dossi Muñoz, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2014)
      Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR- ) ...
    • N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation ... 
      Tapia Opazo, Gladys; Valenzuela, Rodrigo; Espinosa, Alejandra; Romanque, Pamela; Dossi, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (Wiley-VCH Verlag, 2014)
      Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR-α) and ...
    • Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion ... 
      Hernández Cáceres, María Paz; Cereceda, Karina; Hernández, Sergio; Li, Ying; Narro, Carla; Rivera, Patricia; Silva, Patricio; Ávalos, Yenniffer; Jara, Claudia; Burgos, Paulina; Toledo Valenzuela, Lilian; Lagos, Pablo; Cifuentes Araneda, Flavia; Pérez Leighton, Claudio; Bertocchi, Cristina; Clegg, Deborah J.; Criollo Céspedes, Alfredo; Tapia Rojas, Cheril; Burgos, Patricia V.; Morselli, Eugenia (Taylor & Francis, 2020)
      High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed ...
    • Reduction in the desaturation capacity of the liver in mice subjected to high fat diet: Relation to LCPUFA ... 
      Valenzuela Báez, Rodrigo; Barrera Ramírez, Cynthia; Espinosa, Alejandra; Llanos Vidal, Paola; Orellana, Paula; Videla Cabrera, Luis (Elsevier, 2015)
      alpha-Linolenic (ALA) and linoleic (LA) acids are precursors of long chain polyunsaturated fatty acids (LCPUFAs), FAs with important biochemical and physiological functions. In this process, desaturation reactions catalyzed ...
    • Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol ... 
      Echeverría, F.; Valenzuela, R.; Espinosa, A.; Bustamante, A.; Álvarez, D.; González Mañan, Daniel; Ortiz, M.; Soto Alarcón, Sandra A.; Videla Cabrera, Luis (Elsevier Inc., 2019)
      © 2018 Elsevier Inc. High-fat diet (HFD)-fed mice show obesity with development of liver steatosis and a proinflammatory state without establishing an inflammatory reaction. The aim of this work was to assess the hypothesis ...
    • Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic ... 
      Ortiz, Macarena; Soto Alarcón, Sandra; Orellana Manríquez, Paula; Espinosa Escalona, Alejandra; Campos, Cristian; López Arana, Sandra; Rincón Cervera, Miguel Ángel; Illesca, Paola; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (Elsevier, 2020)
      Objective: Obesity-induced by high-fat diet (HFD) is associated with liver steatosis, oxidative stress and mitochondrial dysfunction, which can be eluded by the co-administration of the lipid metabolism modulator docosahexaenoic ...
    • The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle ... 
      Llanos Vidal, Paola; Contreras Ferrat, Ariel; Georgiev, Tihomir; Osorio Fuentealba, César; Espinosa, Alejandra; Hidalgo, Jorge; Hidalgo Tapia, María Cecilia; Jaimovich Pérez, Enrique (American Physiological Society, 2015)
      Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of GLUT4 glucose transporters to the transverse tubule (T-tubule) membranes, which have particularly high cholesterol levels. We ...