Browsing by Subject "Immunogenicity"

Now showing items 1-7 of 7

    • A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells ... 
      Gleisner Muñoz, María Alejandra; Pereda Ramos, Cristián; Tittarelli Elaskar, Andrés; Navarrete Sánchez, Mariela; Fuentes Villegas, Camila; Ávalos, Ignacio; Tempio Sepúlveda, Fabián; Araya, Juan Pablo; Becker, María Inés; González Bergas, Fermín; López Nitsche, Mercedes; Salazar Onfray, Flavio (BMJ, 2020)
      Background Immune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of ...
    • Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization ... 
      Nolan, Terry; Santolaya de Pablo, María Elena; de Looze, Ferdinandus; Marshall, Helen; Richmond, Peter; Henein, Sam; Rheault, Paul; Heaton, Ken; Perrett, Kirsten P.; Garfield, Hartley; Gupta, Anil; Ferguson, Murdo; D'Agostino, Diego; Toneatto, Daniela; O'Ryan, Miguel (Elsevier Ltd, 2019)
      Background: Data on duration of protection against invasive meningococcal disease post-vaccination with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB) are limited. We evaluated bactericidal activity ...
    • Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside 
      Palacios, Miriam; Tampe, Ricardo; Campo, Miguel del; Zhong, Ta-Ying; López, Mercedes N.; Salazar Onfray, Flavio; Becker, María Inés (Elsevier, 2018-04-25)
      Conjugation to carrier proteins is a way to improve the immunogenicity of peptides. Such is the case for peptides mimicking carbohydrate tumor-associated antigens in cancer vaccine development. The most used protein for ...
    • From a pathogen’s genome to an effective vaccine: The four-component meningococcal serogroup b vaccine Del ... 
      Abad, Raquel; Martinón-Torres, Federico; Santolaya de Pablo, María Elena; Banzhoff, Angelika; González-Inchausti, Carmen; Graña, Maria Gabriela; Vázquez, Julio A. (Sociedad Espanola de Quiminoterapia, 2019)
      © 2019, Sociedad Espanola de Quiminoterapia. All rights reserved.Invasive meningococcal disease (IMD), caused by the bacterium Neisseria meningitidis, entails significant mortality and morbidity. Disease incidence is highest ...
    • Immunogenicity of a 23-valent pneumococcal polysaccharide vaccine in elderly residents of a long-term care facility 
      Valenzuela, M. Teresa B.; Altuzarra, Rogelio H.; Trucco, Olivia A.; Villegas, Rodrigo R.; Inostroza, Jaime S.; Granata, Paulo S.; Fleiderman, José V.; Maggi, Leonardo C. (2007)
      S. pneumoniae is a significant cause of community-acquired pneumonia in the elderly, and accounts for the majority of the pneumonia deaths among the elderly. We conducted this randomized double-blind study to evaluate the ...
    • Immunogenicity to biological drugs in psoriasis and psoriatic arthritis 
      Valenzuela, Fernando; Flores, Rodrigo (Hospital Clinicas, Brasil, 2021)
      Monoclonal antibodies or fusion proteins, defined as biological drugs, have modified the natural history of numerous immune-mediated disorders, allowing the development of therapies aimed at blocking the pathophysiological ...
    • Immunomodulatory and immunogenic properties of mesenchymal stem cells derived from bovine fetal bone marrow ... 
      Huaman, Olger; Bahamonde, Javiera; Cahuascanco, Berly; Jervis, Miguel; Palomino, Jaime; Torres, Cristian G.; Peralta, Oscar A. (Elsevier B.V., 2019)
      Little information is currently available on therapeutic features of bovine mesenchymal stem cells (MSCs), despite the development of large animal experimental models including cattle may open alternative strategies for ...