Now showing items 1-10 of 10

    • Sotomayor Flores, Cristian; Rivera Mejías, Pablo; Vásquez Trincado, César; López Crisosto, Camila; Morales, Pablo E.; Pennanen, Christian; Polakovicova, Iva; Aliaga Tobar, Víctor; García Nannig, Lorena; Roa, Juan Carlos; Rothermel, Beverly A.; Maracaja Coutinho, Vinicius; Ho-Xuan, Hung; Meister, Gunter; Chiong, Mario; Ocaranza, María Paz; Corvalán, Alejandro H.; Parra Ortiz, Valentina; Lavandero González, Sergio (2020)
      Angiotensin-(1-9) is a peptide from the noncanonical renin-angiotensin system with anti-hypertrophic effects in cardiomyocytes via an unknown mechanism. In the present study we aimed to elucidate it, basing us initially ...
    • Carrillo, Ileana; Nonato Rabelo, Rayane Aparecida; Barbosa, César; Rates, Mariana; Fuentes Retamal, Sebastián Andrés; González Herrera, Fabiola; Guzmán Rivera, Daniela Inés; Quintero, Helena; Kemmerling Weis, Ulrike; Castillo, Christian; Machado, Fabiana; Díaz Araya, Guillermo; Maya, Juan (Public Library Science, 2021)
      Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and is widely distributed worldwide because of migration. In 30% of cases, after years of infection and in the absence of treatment, ...
    • Morales, Bernardo; Madrid, Rodolfo; Bacigalupo Vicuña, Juan (1997)
      In toad olfactory neurons, a putrid odorant mixture inducing inhibitory responses increases Ca2+-activated K+ conductance, developing a hyperpolarizing receptor potential. Removal of extracellular Ca2+ or exposure to ...
    • Maureira, Carlos; Letelier Parga, Juan; Álvarez Araya, Osvaldo; Delgado Arriagada, Ricardo; Vergara Montecinos, Cecilia (Wiley & Sons, 2015)
      Copper, an ion with many important metabolic functions, has also been proposed to have a role as modulator on neuronal function, mostly based on its effects on voltage- and neurotransmitter-gated conductance as well as ...
    • Vargas Fernández, Andrés; Sánchez, Marianela; Díaz Soler, Felipe; Vásquez Quitral, Patricio; Yazdani Pedram, Mehrdad; Neira Carrillo, Andrónico (Amer Chemical Soc, 2020)
      The electrocrystallization (EC) of calcium oxalate (CaOx) crystals in the presence of multiwalled carbon nanotubes (MWCNTs) functionalized with itaconic acid (IA) and the monoester derivatives mono-methylitaconate or ...
    • Plotkin, Lilian I.; Buvinic Radi, Sonja; Balanta Melo, Julián (Elsevier, 2020)
      Non-traditional bisphosphonates, that is, bisphosphonates that do not inhibit osteoclast viability or function, were initially reported in the 1990s by Socrates Papapoulos' group. Originally designed to study the role of ...
    • Jarmusch, Scott A.; Lagos Susaeta, Diego Ignacio; Diab, Emtinan; Salazar Aguirre, María Oriana; Asenjo de Leuze de Lancizolle, Juan; Ebel, Rainer; Jaspars, Marcel (Royal Soc. Chemistry, 2021)
      Siderophores are iron-chelating compounds that aid iron uptake, one of the key strategies for microorganisms to carve out ecological niches in microbially diverse environments. Desferrioxamines are the principal siderophores ...
    • Fernández, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido Moreno, Valeria Soraya; Vásquez Trincado, César; Flores Vergara, Raúl Alejandro; López Crisosto, Camila; Ocaranza, María Paz; Chiong Lay, Mario Martin; Pedrozo Cibils, Zully Rocío Evangelina; Lavandero González, Sergio (Public Library Science, 2021)
      Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical ...
    • Cornejo, Alberto; Aguilar Sandoval, Felipe; Caballero, Leonardo; Machuca, Luis; Muñoz, Patricio; Caballero, Julio; Perry, George; Ardiles, Alejandro; Areche Medina, Carlos; Melo, Francisco (Taylor & Francis, 2017)
      Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the disease. Efforts targeting amyloid-b plaques have succeeded to remove plaques but failed in clinical trials to improve ...
    • Schmidt, Jimena; Nien, Jyh Kae; Scherson, Alicia; Campos, Eliseo O.; Cartier Rovirosa, Luis; Alvarez, Jaime (Elsevier Ireland Ltd, 1996)
      Progressive spastic paraparesis (PSP) is a demyelinating disease of the central nervous system. We studied the ability of the cerebrospinal fluid (CSF) of patients to induce alterations in rat peroneal nerves, and to modify ...