Browsing by Subject "Macrophages"

Now showing items 1-20 of 22

    • A simultaneous blow-up problem arising in tumor modeling 
      Espejo, Elio; Vilches, Karina; Conca, Carlos (Springer Verlag, 2019)
      © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.Although macrophages are part of the human immune system, it has been remarkably observed in laboratory experiments that decreasing its number can slow down the ...
    • Autophagy Activation in Zebrafish Heart Regeneration 
      Chávez, Myra; Morales, Rodrigo A.; López Crisosto, Camila; Roa, Juan; Allende Connelly, Miguel; Lavandero González, Sergio (Nature, 2020)
      Autophagy is an evolutionarily conserved process that plays a key role in the maintenance of overall cellular health. While it has been suggested that autophagy may elicit cardioprotective and pro-survival modulating ...
    • Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose ... 
      D'Espessailles Tapia, Amanda; Santillana, Natalia; Sanhueza, Sofía; Fuentes, Cecilia; Cifuentes Koster, Mariana (Elsevier, 2020)
      Excess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in ...
    • CCL2, CCL5, and IGF-1 participate in the immunomodulation of osteogenesis during M1/M2 transition in vitro 
      Córdova Jara, Luis; Loi, Florence; Lin, Tzu-Hua; Gibon, Emmanuel; Pajarinen, Jukka; Nabeshima, Akira; Lu, Laura; Yao, Zhenyu; Goodman, Stuart B. (Wiley, 2017)
      The modulation of macrophage phenotype from pro-inflammatory (M1) to tissue healing (M2) via exogenous addition of interleukin-4 (IL-4) facilitates osteogenesis; however, the molecular mediators underlying this phenomenon ...
    • CCR2 Contributes to F4/80+ Cells Migration Along Intramembranous Bone Healing in Maxilla, but Its Deficiency ... 
      Biguetti, Claudia Cristina; Espíndola Vieira, Andreia; Cavalla, Franco; Fonseca, Angélica Cristina; Colavite, Priscila María; Menezes Silva, Renato; Favaro Trombone, Ana Paula; Pompermaier Garlet, Gustavo (Frontiers Media, 2018)
      Bone healing depends of a transient inflammatory response, involving selective migration of leukocytes under the control of chemokine system. CCR2 has been regarded as an essential receptor for macrophage recruitment to ...
    • Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interaction of Salmonella Enteritidis ... 
      Espinoza, Rodrigo A.; Silva Valenzuela, Cecilia A.; Amaya, Fernando A.; Urrutia, ítalo M.; Contreras, Inés; Santiviago, Carlos A. (BioMed Central, 2017)
      Background: Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However, it is absent in typhoid serovars such as S. Typhi and ...
    • Efecto del sulfato de cobre en el daño pulmonar inducido por la exposición crónica intermitente a ozono 
      Oyarzún Gómez, Manuel; Sánchez R., Susan A.; Dussaubat D., Nelson; Miller A., María E.; González B., Sergio (Sociedad Médica de Santiago, 2017)
      Background: Ozone exposure could increase lung damage induced by airborne particulate matter. Particulate matter lung toxicity has been attributed to its metallic content. Aim: To evaluate the acute effect of ...
    • Expression of genes associated with inflammation and iron metabolism in 3T3-L1 cells induced with ... 
      Briones, L.; Andrews, M.; Pizarro Aguirre, Fernando; Arredondo Olguín, Miguel (Springer Netherlands, 2018)
      © 2018, Springer Science+Business Media, LLC, part of Springer Nature. Obesity is characterized by a chronic inflammatory process, with an increased volume of total adipose tissue, especially visceral, which secretes ...
    • Extracts of Chilean native fruits inhibit oxidative stress, inflammation and insulin-resistance linked to ... 
      Reyes-Farias, M.; Vasquez, K.; Fuentes, F.; Ovalle-Marin, A.; Parra-Ruiz, C.; Zamora, O.; Pino, M. T.; Quitral, V.; Jimenez, P.; Garcia, L.; Garcia-Diaz, D. F. (Elsevier Ltd, 2016)
      © 2016 Elsevier Ltd Obesity-associated insulin-resistance is set by a chronic inflammatory state established in the adipose tissue. Chilean native fruits calafate (CA) and maqui (MA) berries present remarkable anti-inflammatory ...
    • Glucocorticoids impair phagocytosis and inflammatory response against crohn's disease-associated adherent-invasive ... 
      Olivares Morales, Mauricio; Fuente, Marjorie de la; Dubois Camacho, Karen; Palominos Parada, Daniela Paz; Díaz Jiménez, David; Torres Riquelme, Alejandro; Xu, Xiaojiang; Chamorro Veloso, Nayaret; Naves, Rodrigo; González Burgos, María Julieta; Quera Pino, Rodrigo; Figueroa, Carolina; Cidlowski, John Anthony; Vidal, Roberto; Hermoso Ramello, Marcela (Frontiers Media, 2018)
      Crohn's disease (CD) is a chronic inflammatory bowel disorder characterized by deregulated inflammation triggered by environmental factors Notably, adherent-invasive Escherichia coli (AIEC), a bacterium with the ability ...
    • IFPA meeting 2016 workshop report III: Decidua trophoblast interactions; trophoblast implantation and ... 
      Aplin, John D.; Beristain, Alexander; Da Silva Arnold, Sonia; Dunk, Caroline; Duzyj, Christina; Golos, Thaddeus G.; Kemmerling Weis, Ulrike; Knoefler, Martin; Mitchell, Murray D.; Olson, David M.; Petroff, Margaret; Pollheimer, Juergen; Reyes, Leticia; Schedin, Pepper; Soares, Michael J.; Stencel Baerenwald, Jennifer; Thornburg, Kent L.; Lash, Gendie E. (Elsevier, 2017)
      Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2016 there were twelve themed workshops, four of which are summarized in this report. These ...
    • Interferon-γ, interleukins-6 and -4, and factor XIII-A as indirect markers of the classical and alternative ... 
      Navarrete, Mariely; García, Jocelyn; Dutzan, Nicolás; Henríquez, Leslie; Puente, Javier; Carvajal, Paola; Hernandez, Marcela; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2014)
      Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ ...
    • Maqui, Calafate, and Blueberry fruits extracts treatments suppress the pathogenic interaction amongst human ... 
      Ovalle Marín, A.; Reyes Farías, M.; Vásquez, K.; Parra Ruiz, C.; Quitral, V.; Jiménez, P.; García, L.; Ramírez, L. A.; Quezada, J.; González Muniesa, P.; García Díaz, D. F. (IOS Press, 2020)
      BACKGROUND: Obesity occurs due to a positive energy imbalance, leading to the expansion of adipose tissue. This phenomenon triggers a chronic low-grade inflammatory state, which is associated with comorbidities development. ...
    • Neosaxitoxin inhibits the expression of inflammation markers of the M1 Phenotype in macrophages 
      Montero Sepúlveda, María Cecilia; Campo, Miguel del; Bono Merino, María Rosa; Simon Zegers, María Valeska; Guerrero Peralta, Julia; Lagos Wilson, Néstor (MDPI, 2020)
      Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide ...
    • New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages 
      Batista González, Ana; Vidal Álvarez, Roberto; Criollo Céspedes, Alfredo; Carreño Márquez, Leandro (Frontiers Media, 2020)
      Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
    • Productive infection of Piscirickettsia salmonis in macrophages and monocyte-like cells from rainbow trout, ... 
      Rojas, Verónica; Galanti Garrone, Norbel; Bols, Niels C.; Marshall, Sergio H. (2009)
      Piscirickettsia salmonis is the etiologic agent of the salmonid rickettsial septicemia (SRS), an endemic disease which causes significant losses in salmon production. This intracellular bacterium is normally cultured in ...
    • Pure platelet-rich plasma and supernatant of calcium-activated P-PRP induce different phenotypes of human ... 
      Escobar, Gisselle; Escobar Álvarez, Alejandro; Ascui, Gabriel; Tempio, Fabián I.; Ortiz, María C.; Pérez Núñez, Claudio; López, Mercedes N. (Future Medicine, 2018)
      Aim: This study aimed to evaluate the effect of two platelet preparations used in the clinic, pure platelet-rich plasma (P-PRP) and the supernatant of calcium-activated P-PRP (S-PRP), on the phenotype of human macrophages. ...
    • Salmonella typhimurium triggers extracellular traps release in murine macrophages 
      Mónaco, Amy; Canales Huerta, Nicole Catalina; Jara Wilde, Jorge Francisco; Hartel, Steffen; Chabalgoity, José Alejandro; Moreno, María; Scavone, Paola (MDPI, 2021)
      Salmonella comprises two species and more than 2500 serovars with marked differences in host specificity, and is responsible for a wide spectrum of diseases, ranging from localized gastroenteritis to severe life-threatening ...
    • Steroidogenic capacity and oxidative stress-related parameters in human luteal cell regression 
      Vega Blanco, María Margarita; Castillo, Teresita; Retamales, Iván; Las Heras, Jorge; Devoto, Luigi; Videla Cabrera, Luis (1994)
      The steroidogenic capacity and oxidative stress-related parameters of the human corpus luteum (CL) at different stages of the luteal phase were studied under basal and human chorionic gonadotropin (hCG)-stimulated conditions. ...
    • Study of a classification algorithm for AIEC identification in geographically distinct E. coli strains 
      Camprubí Font, Carla; Bustamante Ara, Paula; Vidal Álvarez, Roberto; O’Brien, Claire L.; Barnich, Nicolas; Martínez Medina, Margarita (Nature, 2020)
      Adherent-invasive Escherichia coli (AIEC) have been extensively implicated in Crohn's disease pathogenesis. Currently, AIEC is identified phenotypically, since no molecular marker specific for AIEC exists. An algorithm ...