Browsing by Subject "Micrornas"

Now showing items 1-3 of 3

    • Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA ... 
      Sotomayor Flores, Cristian; Rivera Mejías, Pablo; Vásquez Trincado, César; López Crisosto, Camila; Morales, Pablo E.; Pennanen, Christian; Polakovicova, Iva; Aliaga Tobar, Víctor; García Nannig, Lorena; Roa, Juan Carlos; Rothermel, Beverly A.; Maracaja Coutinho, Vinicius; Ho-Xuan, Hung; Meister, Gunter; Chiong, Mario; Ocaranza, María Paz; Corvalán, Alejandro H.; Parra Ortiz, Valentina; Lavandero González, Sergio (2020)
      Angiotensin-(1-9) is a peptide from the noncanonical renin-angiotensin system with anti-hypertrophic effects in cardiomyocytes via an unknown mechanism. In the present study we aimed to elucidate it, basing us initially ...
    • Statins differentially modulate microRNAs expression in peripheral cells of hyperlipidemic subjects: A pilot study 
      Zambrano Coloma, Tomás; Hirata, Rosario D. C.; Hirata, Mario H.; Cerda, Álvaro; Salazar, Luis A. (Elsevier, 2018)
      Aim: Although statins are considered a cornerstone for the treatment of high cholesterol levels due to their powerful cholesterol-lowering effects, response to drug administration is still one of the main pitfalls of statin ...
    • T cell exosome–derived miR-142-3p impairs glandular cell function in Sjögren’s syndrome 
      Cortes Troncoso, Juan; Jang, Shyh-Ing; Pérez, Paola; Hidalgo, Jorge; Ikeuchi, Tomoko; Greenwell-Wild, Teresa; Warner, Blake M.; Moutsopoulos, Niki M.; Alevizos, Ilias (The American Society for Clinical Investigation, 2020)
      Sjogren's syndrome (SS) is a systemic autoimmune disease that mainly affects exocrine salivary and lacrimal glands. Local inflammation in the glands is thought to trigger glandular dysfunction and symptoms of dryness. ...