Browsing by Subject "Microsatellite instability"

Now showing items 1-3 of 3

    • Consensus molecular subtypes of colorectal cancer in clinical practice: a translational approach 
      Valenzuela Torreblanca, Guillermo Ignacio; Cánepa González, Joaquín Alfredo; Simonetti Izquierdo, Carolina Andrea; Solo de Zaldivar, Loreto; Marcelain Cubillos, Katherine Jenny; González Montero, Jaime Alfredo (Baishideng, 2021)
      The identification of several genetic mutations in colorectal cancer (CRC) has allowed a better comprehension of the prognosis and response to different antineoplastic treatments. Recently, through a systematic process, ...
    • Muir-Torre Syndrome: Case report and molecular characterization Síndrome de Muir-Torre: Relato de caso e ... 
      Rios, Carolina Alejandra; Villalón, Ricardo; Muñoz, Jorge; Acuña, Mónica; Cifuentes, Lucía (2014)
      CONTEXT: Muir-Torre syndrome is a rare autosomal dominant genodermatosis caused by mutations in the mismatch repair genes. It is characterized by the presence of sebaceous skin tumors and internal malignancies, affecting ...
    • Spectrum of MLH1 and MSH2 mutations in Chilean Families with suspected Lynch syndrome 
      Alvarez, Karin; Hurtado, Claudia; Hevia, Montserrat A.; Wielandt, Ana Maria; De La Fuente, Marjorie; Church, James; Carvallo, Pilar; López Kostner, Francisco (2010)
      PURPOSE: Lynch syndrome is the most common inherited syndrome of colorectal cancer, caused principally by germline mutations in MLH1 and MSH2. We report our experience with genetic screening in the diagnosis of Lynch ...