Browsing by Subject "NMDA receptor"
Now showing items 1-7 of 7
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(2008)We assessed whether intrathecal administration of the uncompetitive and competitive NMDA receptor antagonists ketamine and (±)CPP, respectively, could produce differential modulation on chemical and mechanical nociception ...
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(Wiley-Blackwell, 2016)The generation of abnormally high levels of reactive oxygen species (ROS) is linked to cellular dysfunction, including neuronal toxicity and neurodegeneration. However, physiological ROS production modulates redox-sensitive ...
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(2006)Recent evidence suggests that reactive oxygen species function as second messenger molecules in normal physiological processes. For example, activation of N-Methyl-D-Aspartate receptor results in the production of ROS, ...
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(Elsevier, 2015)Pannexin 1 (Panx1) is a glycoprotein that acts as a membrane channel in a wide variety of tissues in mammals. In the central nervous system (CNS) Panx1 is expressed in neurons, astrocytes and microglia, participating in ...
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(2004)Protein kinase CK2 (CK2) is highly expressed in rat forebrain where its function is not well understood. Subcellular distribution studies showed that the catalytic subunit of CK2 (CK2α) was enriched in postsynaptic densities ...
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(Universidad de Chile, 2017)
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(Springer New York LLC, 2005)Recent studies show that inflammation has an active role in the onset of neurodegenerative diseases. It is known that in response to extracellular insults microglia and/or astrocytes produce inflammatory agents. These ...