Now showing items 1-11 of 11

    • Rodríguez, Juan Pablo; Astudillo, Pablo; Ríos, Susana; Seitz, Germán; Pino, Ana María (2009)
      Mesenchymal stem cells (MSCs) found in bone marrow stroma, are able to differentiate into osteoblasts and adipocytes, among other cell phenotypes. In normal bone marrow balanced osteoblastic an adipocytic cell differentiation ...
    • Santos, José Luis; Lera Marques, Lydia; Pérez Bravo, Francisco; Albala Brevis, Cecilia (2006)
      Background: It has been proposed that the toll-like receptor-4 gene (TLR4) may participate in the development of obesity and osteoporosis, in addition to its well-known role in the immune response. On the other hand, the ...
    • Sambrook, P. N.; Rodriguez, J. P.; Wasnich, R. D.; Luckey, M. M.; Kaur, A.; Meng, L.; Lombardi, A. (Springer London, 2004)
      In a 3-year study followed by a 2-year open-label extension, alendronate sodium (ALN) maintained or increased bone mineral density (BMD) in 445 recently postmenopausal women with a spine BMD T-score > -2. In a second ...
    • Gómez, A. B.; Magaña, J. J.; Cisneros, B.; Pérez-Salazar, E.; Faugeron, S.; Véliz, D.; Castro, C.; Rubio, J.; Casas, L.; Valdés-Flores, Margarita (2007)
      The estrogen receptor gene (ERα) has been implicated in the development of osteoporosis. In this study, the association of two ERα gene polymorphic markers (a TA dinucleotide repeat and a single nucleotide polymorphism, ...
    • Blanco, E.; Burrows, Raquel; Reyes, M.; Lozoff, Betsy; Gahagan, S.; Albala Brevis, Cecilia (Springer London, 2017)
      © 2017, International Osteoporosis Foundation and National Osteoporosis Foundation. Summary: Little is known regarding the relationship between early life factors and bone mineral density (BMD). We found a positive association ...
    • Astudillo Besnier, Pablo Andres (Universidad de Chile, 2008)
      En esta tesis se estudio el perfil de expresión y fosforilación de PPARy durante el proceso de diferenciación adipogénica, en MSCs obtenidas desde la médula ósea de mujeres postmenopáusicas sanas y osteoporóticas,
    • Rodríguez, Juan Pablo; Astudillo, Pablo; Ríos, Susana; Pino, Ana María (2008)
      Mesenchymal Stem Cells (MSCs) from bone marrow stroma are capable of differentiating into osteoblasts and adipocytes, among other cell phenotypes. In normal bone marrow osteoblastic and adipocytic cell differentiation occur ...
    • Blumel Méndez, Juan; Arteaga, Eugenio; Aedo, Sócrates; Arriola Montenegro, José; López, Marcela; Martino, Mabel; Miranda, Carlos; Miranda, Octavio; Mostajo, Desiree; Nanez, Mónica; Ojeda, Eliana; Pilnik, Susana; Rojas, José; Salinas, Carlos; Sosa, Lida; Spritzer, Poli M.; Tserotas, Konstantinos; Vallejo, María; Belardo, Alejandra; Fighera, Tayane; Chedraui, Peter (Taylor & Francis, 2020)
      Metformin may decrease cell senescence, including bone; hence we aimed at evaluating the association between metformin use and osteoporosis. This was a cross-sectional study carried out in 1259 Latin American adult women ...
    • Albala Brevis, Cecilia; Yáñez, M.; Devoto, Enzo; Sostin, C.; Zeballos, L.; Santos, J. L. (1996)
      Background: Obesity is considered a protective factor for osteoporosis improving bone mass and maintaining higher levels of estrogen during menopause. Objective: To determine the association of obesity with bone mineral ...
    • Blumel Mendez, Juan Enrique; Arteaga, Eugenio; Vallejos, Maria Soledad; Chea Vine, Rosa Isabel (Springer, 2019)
      The world population is aging, so it is not uncommon that diseases associated with old age are steadily increasing. Osteoporosis and sarcopenia are two disorders that seriously impair the quality of life in the elderly. ...
    • Blümel, Juan Enrique; Arteaga, Eugenio (Sociedad Medica de Santiago, 2017)
      © 2017, Sociedad Medica de Santiago. All rights reserved. Menopause is associated with several symptoms which, if they reach certain intensity, can severely impair the quality of life. Overall, 90.9% of Latin American women ...