Browsing by Subject "Oxidative damage"

Now showing items 1-6 of 6

    • An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells 
      Núñez Millacura, Claudia; Tapia, Victoria; Muñoz, Patricia; Maccioni Baraona, Ricardo; Núñez González, Marco (2002)
      Intracellular reactive iron is a source of free radicals and a possible cause of cell damage. In this study, we analyzed the changes in iron homeostasis generated by iron accumulation in neuroblastoma (N2A) cells and ...
    • Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 
      Urrutia, Pamela J.; Aguirre, Pabla; Tapia, Victoria; Carrasco, Carlos M.; Mena, Natalia P.; Núñez González, Marco (Elsevier, 2017)
      Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of neurodegenerative processes. The question arises as to whether ...
    • Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1 
      Urrutia, Pamela J.; Aguirre, Pabla; Tapia, Victoria; Carrasco, Carlos M.; Mena, Natalia P.; Núñez González, Marco (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. Mitochondrial dysfunction and oxidative damage, often accompanied by elevated intracellular iron levels, are pathophysiological features in a number of neurodegenerative processes. The question arises ...
    • Hepcidin attenuates amyloid beta-induced inflammatory and pro-oxidant responses in astrocytes and microglia 
      Urrutia, Pamela J.; Hirsch, Etienne C.; González Billault, Christian; Núñez González, Marco (Wiley, 2017)
      Alzheimer's disease (AD) is characterized by extracellular senile plaques, intracellular neurofibrillary tangles, and neuronal death. Aggregated amyloid-beta (A beta) induces inflammation and oxidative stress, which have ...
    • Indoor swimming for 2.5 Km decreases nitrite and pH in exhaled breath condensate 
      Araneda, O. F.; Calderón, A.; Terreros, L.; Cavada Chacón, Gabriel (RedIRIS, 2020)
      OBJECTIVE: to determine the effect of an aerobic swimming test in a chlorinated indoor swimming pool on the concentration of NO2-, H2O2 and pH in exhaled breath condensate. METHODS: ten amateur swimmers swam 2.5 km in a ...
    • Iron-induced oxidative damage in colon carcinoma (Caco-2) cells 
      Núñez González, Marco; Tapia, Victoria; Toyokuni, Shinya; Okada, Shigeru (Harwood Academic Publishers GmbH, 2001)
      Intestinal epithelial cells have an active apical iron uptake system that is involved in the regulated absorption of iron. By the action of this system, intestinal cells acquire increasing amounts of iron with time. Since ...