Now showing items 1-20 of 24

    • Merino, Paulina M.; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando (2011)
      Polycystic ovarian syndrome (PCOS) is a lifelong disorder characterized by hyperandrogenism and ovulatory dysfunction, with a wide spectrum of clinical symptoms and signs. Three different sets of diagnostic criteria have ...
    • Iñíguez Vila, Germán; Torrealba, Isabel M.; Ávila, Alejandra; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (2008)
      Aim: To study the adiponectin levels during puberty in girls with type 1 diabetes mellitus (DM1) and their relationship to body mass index (BMI), Tanner stage, ovarian volume (OV), and androgen levels. Methods: We studied ...
    • Gaete, Ximena; García, Roberto; Riquelme, Joel; Codner Dujovne, Ethel (Sociedad Medica de Santiago, 2015)
      © 2015, Rev Med Chile. All rights reserved. Background A secular trend towards a younger age of puberty onset has been reported in Chilean girls. Aim: To evaluate the age of onset of puberty and prevalence of early puberty ...
    • Michels, Karin B.; Keller, Kristen; Pereira, Ana; Kim, Claire E.; Santos, José L.; Shepherd, John A.; Corvalán, Camila; Binder, Alexandra M. (BMC, 2020)
      Background Systemic inflammation may play a role in shaping breast composition, one of the strongest risk factors for breast cancer. Pubertal development presents a critical window of breast tissue susceptibility to exogenous ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Calafat, Antonia M.; Ye, Xiaoyun; Mericq, Verónica; Pereira Scalabrino, Ana; Michels, Karin B. (BIOMED Central Ltd., 2018)
      Background: The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposure ...
    • Gaskins, Audrey J.; Pereira Scalabrino, Ana; Quintiliano Scarpelli, Daiana; Shepherd, John A.; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila; Michels, Karin B. (American Society for Nutrition, 2017-05-01)
      Background: Frequent dairy consumption in childhood has been related to higher growth-hormone concentrations that may affect mammary gland and pubertal development. Objective: We evaluated the relation of dairy intake ...
    • Witchel, Selma F.; Oberfield, Sharon; Rosenfield, Robert L.; Codner Dujovne, Ethel; Bonny, Andrea; Ibáñez, Lourdes; Pena, Alexia; Horikawa, Reiko; Gómez Lobo, Verónica; Joel, Dipesalema; Tfayli, Hala; Arslanian, Silva; Dabadghao, Preeti; García Rudaz, Cecilia; Lee, Peter A. (Karger AG, 2015)
      Background/Aims: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may be normal pubertal physiological ...
    • Merino, Paulina; Schulin Zeuthen, Carolina; Codner Dujovne, Ethel (2009)
      Polycystic ovarian syndrome (PCOS), includes a wide spectrum of clinical symptoms and signs. Three different diagnostic classifications have been proposed to define this disease. The first one, published in 1990, known ...
    • Grinspon, R. P.; Bedecarrás, P.; Ballerini, M. G.; Iñíguez Vila, Germán; Rocha, A.; Mantovani Rodrigues Resende, E. A.; Brito, V. N.; Milani, C.; Figueroa Gacitúa, V.; Chiesa, A.; Keselman, A.; Gottlieb, S.; Borges, M. F.; Ropelato, M. G.; Picard, J. Y.; Codner Dujovne, Ethel; Rey, R. A. (2011)
      Male patients with an extra sex chromosome or autosome are expected to present primary hypogonadism at puberty owing to meiotic germ-cell failure. Scarce information is available on trisomy 21, a frequent autosomal aneuploidy. ...
    • Codner Dujovne, Ethel (2008)
      Patients with type 1 diabetes mellitus (T1DM) face an array of difficulties during puberty which tend to be more significant in females. Excessive weight and fat mass gain, deterioration of metabolic control, loss of height ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Codner Dujovne, Ethel; Merino, P. M.; Tena-Sempere, M. (2012)
      Background: The functional reproductive alterations seen in women with type 1 diabetes (T1D) have changed as therapy has improved. Historically, patients with T1D and insufficient metabolic control exhibited a high prevalence ...
    • Burrows, Raquel; Leiva Balich, Laura; Weisstaub, Gerardo; Lera Marques, Lydia; Albala Brevis, Cecilia; Blanco, Estela; Gahagan, Sheila (2011)
      Objective: To determine how the homeostasis model assessment of insulin resistance (HOMA-IR) is related to metabolic risk in a sample of overweight and obese Chilean youths accounting for Tanner stage. Methods: A cross-sectional ...
    • Mesa Valencia, Diana Carolina; Mericq, Verónica; Corvalán Aguilar, Camila; Pereira Scalabrino, Ana (Taylor & Francis, 2020)
      Purpose: Recent reports show that girls with higher body mass index (BMI) have an earlier puberty onset (thelarche). It has been suggested that earlier puberty is a consequence of higher levels of estrogen due to increased ...
    • Codner Dujovne, Ethel; Mericq, Verónica; Cassorla Goluboff, Fernando (1997)
      During puberty, growth hormone (GH)-deficient children may experience difficulties achieving an appropriate pubertal growth spurt. We review the complex hormonal interactions which occur during puberty. At least two ...
    • Eyzaguirre, Francisca C.; Bancalari, Rodrigo; Youlton, Ronald; Román, Rossana; Silva, Ricardo; García, Hernán; Mericq, Verónica (2009)
      Background: Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an ...
    • Fernández, M.; Pereira, A.; Corvalán, C.; Mericq, Verónica (Springer International Publishing, 2019)
      © 2018, Italian Society of Endocrinology (SIE).Purpose: Puberty onset exhibits remarkable inter-individual and ethnic differences. 5% of Chileans are indigenous but puberty ethnic disparities have not been studied. We aim ...
    • Codner Dujovne, Ethel; Román, Rossana (2008)
      Premature thelarche is a benign condition, which has been described as a "variant of puberty". Early breast development is especially prevalent during the first year of life, when the gonadal axis is usually active. ...
    • Cediel, Gustavo; Corvalán Aguilar, Camila; López de Romaña, Daniel; Mericq, Verónica; Uauy Dagach-Imbarack, Ricardo (Amer Acad Pediatrics, 2016)
      OBJECTIVE: To evaluate the following from prepuberty to the puberty-onset: (1) changes in serum 25-hydroxyvitamin-D (25[OH]D), adiposity, and insulin resistance (IR); (2) the effect of prepubertal adiposity on serum 25(OH)D ...
    • Valenzuela, Carlos Y. (1983)
      Students aged 6 to 20 years attending the public schools in the Northern Area of Santiago, Chile, were examined to search for the developmental origin of the large sex dimorphism in adult stature found in this population. ...