Browsing by Subject "Rac1"

Now showing items 1-5 of 5

    • A novel caveolin-1/p85α/Rab5/Tiam1/Rac1 signaling axis in tumor cell migration and invasion 
      Díaz, Jorge; Mendoza, Pablo; Silva, Patricio; Quest, Andrew F. G.; Torres, Vicente A. (Landes Bioscience, 2014)
      © Jorge Díaz, Pablo endoza, Patricio Silva, Andrew FG Quest, and Vicente A Torres. The small GTPase Rab5 has been frequently studied in the context of intracellular trafficking, but evidence obtained more recently has ...
    • Crosstalk between Rac1- mediated actin regulation and ROS production 
      Acevedo, Alejandro; González Billault, Christian (Elsevier, 2018)
      The small RhoGTPase Rac1 is implicated in a variety of events related to actin cytoskeleton rearrangement. Remarkably, another event that is completely different from those related to actin regulation has the same relevance; ...
    • K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and ... 
      Canales, Jimena; Cruz, Pablo; Villacura Díaz, Nicolás Esteban; Riquelme, Denise; Leiva Salcedo, Elias; Cerda Arancibia, Óscar (MDPI, 2020)
      Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling. Interestingly, ubiquitination ...
    • Rab5 is required in metastatic cancer cells for caveolin-1-enhanced Rac1 activation, migration and invasion 
      Díaz, Jorge; Mendoza, Pablo; Ortiz, Rina; Díaz, Natalia; Leyton Campos, Lisette; Stupack, Dwayne; Quest, Andrew F. G.; Torres, Vicente A. (Company of Biologists Ltd, 2014)
      Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is ...
    • The role of small GTPases in neuronal morphogenesis and polarity 
      González Billault, Christian; Muñoz Llancao, Pablo; Henríquez, Daniel R.; Wojnacki, José; Conde, Cecilia; Cáceres, Alfredo (2012)
      The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton support neuronal morphogenesis. Small RhoGTPases family members have emerged as crucial regulators of cytoskeletal dynamics. In this ...