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Estudio radiográfico de la variabilidad morfológica del seno frontal con fines identificatorios en un grupo de jóvenes chilenos
(Universidad de Chile, 2009)
UNIVERSIDAD DE CHILE
FACULTAD DE ODONTOLOGÍA
DEPARTAMENTO DE PATOLOGÍA
ÁREA DE MEDICINA LEGAL ODONTOLÓGICA
“ESTUDIO RADIOGRÁFICO DE LA VARIABILIDAD
MORFOLÓGICA DEL SENO FRONTAL CON FINES
IDENTIFICATORIOS...
: Dr. Jorge Pinares Toledo Santiago – Chile 2009 1 2 UNIVERSIDAD DE CHILE FACULTAD DE ODONTOLOGÍA DEPARTAMENTO DE PATOLOGÍA ÁREA DE MEDICINA...
: Dr. Jorge Pinares Toledo Santiago – Chile 2009 1 2 UNIVERSIDAD DE CHILE FACULTAD DE ODONTOLOGÍA DEPARTAMENTO DE PATOLOGÍA ÁREA DE MEDICINA...
Musicoterapia y cáncer : la expresión como herramienta de acompañamiento terapéutico en etapa terminal
(Universidad de Chile, 2018)
Terminal 40
Proceso Terapéutico 43
Caso de C 43
Contexto 43
Presentación del caso clínico: 44
Identificación: 44
Antecedentes familiares 44
Antecedentes clínicos 46
Antecedentes musicales 49
Objetivos: 50
Objetivos generales 50
Objetivos...
aborda el proceso musicoterapéutico de forma descriptiva de las tres fases o etapas y, por otro lado, se presenta la evidencia e impacto de la terapia en la paciente expresada por los familiares más directos como actores del proceso. Las...
aborda el proceso musicoterapéutico de forma descriptiva de las tres fases o etapas y, por otro lado, se presenta la evidencia e impacto de la terapia en la paciente expresada por los familiares más directos como actores del proceso. Las...
El Sistema de Salud de Chile: una tarea pendiente
(Sociedad Médica de Santiago, 2015)
Disorders; Life expectancy; Maternal Mortality; National Health Service; Public
Health.
Profesor Emérito, Universidad
de Chile.
Editor Emérito, Revista Médica
de Chile.
Miembro de Número y ex
Presidente, Academia Chilena
de Medicina.
Artículo por...
invitación de los Editores. Conflictos de intereses: ninguno que declarar. Correspondencia a: Dr. Alejandro Goic G. Academia Chilena de Medicina Almirante Montt 453, Santiago de Chile. Teléfono: 22 685 44 17. alejandrogoicster@gmail.com Es un tópico decir...
invitación de los Editores. Conflictos de intereses: ninguno que declarar. Correspondencia a: Dr. Alejandro Goic G. Academia Chilena de Medicina Almirante Montt 453, Santiago de Chile. Teléfono: 22 685 44 17. alejandrogoicster@gmail.com Es un tópico decir...
Sentipensando el género, las espiritualidades y la Tierra: Una comunidad de afinidad de mujeres medicina en Santiago de Chile
(Universidad de Chile, 2017)
La presente investigación pretende develar las prácticas y discursos ecológico-espirituales que se construyen en torno a la comunidad de afinidad de mujeres medicina de la Región Metropolitana de Chile, a través de un estudio de corte cualitativo...
Estudio de asociación entre los alelos de baja penetrancia rs3803662 (TOX3), rs13387042 (2q35) y rs13281615 (8q24) y aumento del riesgo para cáncer de mama, en población chilena
(Universidad de Chile, 2013-01)
patología, siendo la historia familiar de CM el más importante. Actualmente se ha establecido que la predisposición heredada al CM, involucra la participación de 3 categorías de alelos de susceptibilidad, de acuerdo al perfil de riesgo que ellos confieren: 1...
Worldwide, breast cancer (BC) is the most common and the leading cause of death by cancer in women, accounting for 23% of all new cancer cases and 14% of all cancer deaths. In Chile, it is also the leading cause of death by cancer in women, and mortality from this cause, has been increasing in the last two decades. Although the exact etiology of BC is unknown, there are many risk factors associated with the development of this disease, family history of BC being the most important. It has now been established that the inherited predisposition to BC, involves the participation of three categories of susceptibility genes, according to the risk profile they give: 1.- High penetrance genes, 2.- Moderate penetrance genes and 3.- Low-penetrance alleles. The latter have been the subject of great interest in various research groups. It relates to single nucleotide polymorphisms (SNPs) that confer low risk for the development of BC and are relatively common in the population; this could explain up to 22% of BC cases where there are no mutations in the genes of high and moderate penetrance currently known. The SNPs rs3803662 (TOX3), rs13387042 (2q35) and rs13281615 (8q24) have been identified as susceptibility alleles with low penetrance for BC in various studies done primarily in European and Asian population, establishing as risk allele the one with the lowest population frequency and describing increases on the risk for development of the disease ranging between 1.05 - 1.65 times. In this thesis, through a case-control study, it was examined the association between these SNPs and the risk of family BC on the Chilean population. For this, it was performed genotyping of SNPs rs3803662, rs13387042 and rs13281615 in 347 cases of BC and on 801 controls. BC cases were divided according to family history of BC (215 cases with family BC (subgroup A), and 132 cases with no family history of BC, and early diagnosis age (≤ 50 years) (subgroup B)). Using statistical software were established genotypic and allelic frequencies of each polymorphism, and analyzed their association with increased risk of BC. Combined genotypes were also carried out between different SNPs studied and the effect of these on the risk of BC was analyzed. The results obtained showed that the T allele of SNP rs3803662 and allele A of SNP rs13387042, were significantly linked with increased risk of BC (OR: 1.44; IC95%: [1.20-1.74]; p <0.0001 and OR: 1.34; IC95%: [1.11-1.61]; p = 0.0009, respectively). Furthermore, it was found that the G allele of SNP rs13281615 (8q24), described in the literature as the risk allele for BC, was the most frequent allele in Chilean population. However, this allele was not associated with increased risk of BC. Regarding combined genotypes among SNPs rs13387042 and rs3803662, rs13281615 and rs3803662, rs13387042 and rs13281615, it was observed that the risk of BC increased as the number of risk alleles increased. Furthermore, in subgroup B, double homozygous risk combined genotype between SNPs rs3803662 and rs13387042 (T/T-A/A), presented additive scale gene interaction. As conclusion of this studies it is postulated that, in Chilean population, the T allele of SNP rs3803662 and A allele of SNP rs13387042, are susceptibility alleles of low penetrance for the development of BC; that the risk they confer increases as it increase the number of risk alleles; and that on young women (≤ 50 years) with no family history of BC, gene interaction exists between rs3803662 and rs13387042....
Worldwide, breast cancer (BC) is the most common and the leading cause of death by cancer in women, accounting for 23% of all new cancer cases and 14% of all cancer deaths. In Chile, it is also the leading cause of death by cancer in women, and mortality from this cause, has been increasing in the last two decades. Although the exact etiology of BC is unknown, there are many risk factors associated with the development of this disease, family history of BC being the most important. It has now been established that the inherited predisposition to BC, involves the participation of three categories of susceptibility genes, according to the risk profile they give: 1.- High penetrance genes, 2.- Moderate penetrance genes and 3.- Low-penetrance alleles. The latter have been the subject of great interest in various research groups. It relates to single nucleotide polymorphisms (SNPs) that confer low risk for the development of BC and are relatively common in the population; this could explain up to 22% of BC cases where there are no mutations in the genes of high and moderate penetrance currently known. The SNPs rs3803662 (TOX3), rs13387042 (2q35) and rs13281615 (8q24) have been identified as susceptibility alleles with low penetrance for BC in various studies done primarily in European and Asian population, establishing as risk allele the one with the lowest population frequency and describing increases on the risk for development of the disease ranging between 1.05 - 1.65 times. In this thesis, through a case-control study, it was examined the association between these SNPs and the risk of family BC on the Chilean population. For this, it was performed genotyping of SNPs rs3803662, rs13387042 and rs13281615 in 347 cases of BC and on 801 controls. BC cases were divided according to family history of BC (215 cases with family BC (subgroup A), and 132 cases with no family history of BC, and early diagnosis age (≤ 50 years) (subgroup B)). Using statistical software were established genotypic and allelic frequencies of each polymorphism, and analyzed their association with increased risk of BC. Combined genotypes were also carried out between different SNPs studied and the effect of these on the risk of BC was analyzed. The results obtained showed that the T allele of SNP rs3803662 and allele A of SNP rs13387042, were significantly linked with increased risk of BC (OR: 1.44; IC95%: [1.20-1.74]; p <0.0001 and OR: 1.34; IC95%: [1.11-1.61]; p = 0.0009, respectively). Furthermore, it was found that the G allele of SNP rs13281615 (8q24), described in the literature as the risk allele for BC, was the most frequent allele in Chilean population. However, this allele was not associated with increased risk of BC. Regarding combined genotypes among SNPs rs13387042 and rs3803662, rs13281615 and rs3803662, rs13387042 and rs13281615, it was observed that the risk of BC increased as the number of risk alleles increased. Furthermore, in subgroup B, double homozygous risk combined genotype between SNPs rs3803662 and rs13387042 (T/T-A/A), presented additive scale gene interaction. As conclusion of this studies it is postulated that, in Chilean population, the T allele of SNP rs3803662 and A allele of SNP rs13387042, are susceptibility alleles of low penetrance for the development of BC; that the risk they confer increases as it increase the number of risk alleles; and that on young women (≤ 50 years) with no family history of BC, gene interaction exists between rs3803662 and rs13387042....
Efecto de la Reforma Educacional en la demanda por Educación Superior
(Universidad de Chile, 2017)
facti-
ble de decisiones se agrandó, por lo que habrá una competencia más agresiva para las
carreras con mejores perspectivas futuras, como Medicina, Ingeniería Civil, Odontología,
entre otras opciones.
2
1.1.2. Implementación de la Reforma
En 2016, 302...
diferentes por carreras y por universidades. Por ejemplo, la carrera de Arquitectura, que se imparte tanto en la Universidad de Chile como en la Universidad Católica, no tienen las mismas ponderaciones sobre las pruebas. De la misma forma, Medicina e...
diferentes por carreras y por universidades. Por ejemplo, la carrera de Arquitectura, que se imparte tanto en la Universidad de Chile como en la Universidad Católica, no tienen las mismas ponderaciones sobre las pruebas. De la misma forma, Medicina e...
Reanimación cardiopulmonar del adulto
(2020)
de Habilidades Clínicas, Profesor Asociado
del Departamento de Medicina Occidente, Facultad de Medicina, Universidad de Chile.
Correo de contacto: sbozzo@uchile.cl
Claudia Arancibia Salvo, Fonoaudiologa, Academico Centro de Habilidades Clínicas...
, Profesora Asistente del Departamento de Fonoaudiología, Facultad de Medicina, Universidad de Chile. Correo de contacto: carancibia@uchile.cl Leonardo Pérez González, Kinesiologo, Academico Centro de Habilidades Clínicas, Doctor en Ciencias Biomedicas...
, Profesora Asistente del Departamento de Fonoaudiología, Facultad de Medicina, Universidad de Chile. Correo de contacto: carancibia@uchile.cl Leonardo Pérez González, Kinesiologo, Academico Centro de Habilidades Clínicas, Doctor en Ciencias Biomedicas...
Argumentos éticos a favor y en contra de la participación del profesional médico en la muerte asistida. Análisis del Departamento de Ética del Colegio Médico de Chile
(Sociedad Médica Santiago, 2020)
,
Assisted.
1Departamento de Ética del
Colegio Médico de Chile A.G.
Santiago, Chile.
2Centro de Bioética, Facultad
de Medicina, Clínica Alemana
Universidad del Desarrollo.
Santiago, Chile.
3Departamento de Ciencias
Neurológicas, Universidad de
Chile...
. Santiago, Chile. 4División de Obstetricia y Ginecología, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile. Santiago, Chile. 5Programa Cuidados Paliativos Hospital de Angol. Angol, Chile. 6Departamento de Medicina...
. Santiago, Chile. 4División de Obstetricia y Ginecología, Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile. Santiago, Chile. 5Programa Cuidados Paliativos Hospital de Angol. Angol, Chile. 6Departamento de Medicina...
Estado actual de las especialidades médicas en Chile: realidad en el sistema público no municipalizado
(SOC MEDICA SANTIAGO, 2008-01)
Radiología 6.370 144
Urología 5.275 120
Anatomía Patológica 4.918 112
Otorrinolaringología 4.351 99
Medicina Intensiva 4.112 93
Dermatología 3.047 69
Medicina familiar 2.761 63
Fisiatría y Rehabilitación 2.009 46
Laboratorio Clínico y Bacteriología 1.849 42...
, medical, graduate; Specialties, medical) Recibido el 15 de marzo, 2007. Aceptado el 28 de septiembre, 2007. 1Departamento de Medicina, Campus Centro, Universidad de Chile. 2División de Gestión y Desarrollo de las Personas, Ministerio de Salud. a...
, medical, graduate; Specialties, medical) Recibido el 15 de marzo, 2007. Aceptado el 28 de septiembre, 2007. 1Departamento de Medicina, Campus Centro, Universidad de Chile. 2División de Gestión y Desarrollo de las Personas, Ministerio de Salud. a...
Perfil y número de médicos generales que requiere el país
(Sociedad Médica de Santiago, 2008-09)
Radiología 6.370 144
Urología 5.275 120
Anatomía Patológica 4.918 112
Otorrinolaringología 4.351 99
Medicina Intensiva 4.112 93
Dermatología 3.047 69
Medicina familiar 2.761 63
Fisiatría y Rehabilitación 2.009 46
Laboratorio Clínico y Bacteriología 1.849 42...
, medical, graduate; Specialties, medical) Recibido el 15 de marzo, 2007. Aceptado el 28 de septiembre, 2007. 1Departamento de Medicina, Campus Centro, Universidad de Chile. 2División de Gestión y Desarrollo de las Personas, Ministerio de Salud. a...
, medical, graduate; Specialties, medical) Recibido el 15 de marzo, 2007. Aceptado el 28 de septiembre, 2007. 1Departamento de Medicina, Campus Centro, Universidad de Chile. 2División de Gestión y Desarrollo de las Personas, Ministerio de Salud. a...