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Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles-A New Family of High Affinity CB1 Cannabinoid Ligands
(2013)
Ciencias, Universidad de Chile, Casilla 233, Santiago, Chile
* Author to whom correspondence should be addressed; E-Mail: cpessoa@uc.cl;
Tel.: +56-2-2354-4041; Fax: +56-2-2354-4744.
Received: 26 February 2013; in revised form: 24 March 2013 / Accepted...
Towards battery health management for lithium polymer battery-powered small-size rotary-wing unmanned aerial vehicles
(Universidad de Chile, 2018)
VEHICLES
TESIS PARA OPTAR AL GRADO DE DOCTORA EN INGENIERI´A ELE´CTRICA
GINA KATHERINE SIERRA PA´EZ
PROFESOR GUI´A:
DR. MARCOS ORCHARD CONCHA
CO-GUI´A:
DR. KAI GOEBEL
MIEMBROS DE LA COMISIO´N:
DR. JORGE SILVA SA´NCHEZ
DR. FERNANDO AUAT CHEEIN
DR. EDUARDO...
CERPA JERIA Este trabajo ha sido parcialmente financiado por CONICYT bajo la beca CONICYT-PCHA/Doctorado Nacional/2014-63140178 SANTIAGO DE CHILE 2018 ii THESIS ABSTRACT FOR THE DOCTORAL DEGREE IN ELECTRICAL ENGINEERING BY: GINA KATHERINE SIERRA PA...
CERPA JERIA Este trabajo ha sido parcialmente financiado por CONICYT bajo la beca CONICYT-PCHA/Doctorado Nacional/2014-63140178 SANTIAGO DE CHILE 2018 ii THESIS ABSTRACT FOR THE DOCTORAL DEGREE IN ELECTRICAL ENGINEERING BY: GINA KATHERINE SIERRA PA...
Fungal Planet description sheets: 716–784
(Rijksherbarium, 2018-06)
Mycology Unit, Biomedical Sciences Institute, University of Chile, Santiago,
Chile.
38 Agriculture Victoria, School of Applied Systems Biology, La Trobe Univer-
sity, Bundoora 3083, Victoria, Australia.
39 Instituto de Ciências Biológicas e da Saúde...
Route 130 North, Cinnaminson, NJ 08077, USA. 46 P.O. Box 58499, 3734 Limassol, Cyprus. 47 Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor de Chile, Camino La Pirámide 5750, Huechuraba, Santiago, Chile. 48 Departamento de...
Route 130 North, Cinnaminson, NJ 08077, USA. 46 P.O. Box 58499, 3734 Limassol, Cyprus. 47 Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor de Chile, Camino La Pirámide 5750, Huechuraba, Santiago, Chile. 48 Departamento de...
Expressive Path Queries on Graphs with Data
(Springer, 2015)
Tygar, USA
Advanced Research in Computing and Software Science
Subline of Lectures Notes in Computer Science
Subline Series Editors
Giorgio Ausiello, University of Rome ‘La Sapienza’, Italy
Vladimiro Sassone, University of Southampton, UK
Subline...
Based First-Order Modal Logic Provers . . . . . . . . . . . . . . . . . . . . . . . . 127 Christoph Benzmu¨ller and Thomas Raths Resourceful Reachability as HORN-LA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Josh Berdine, Nikolaj...
Based First-Order Modal Logic Provers . . . . . . . . . . . . . . . . . . . . . . . . 127 Christoph Benzmu¨ller and Thomas Raths Resourceful Reachability as HORN-LA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Josh Berdine, Nikolaj...
Open pit geomechanics and mine planning integration: design & economic assessment of a subsurface slope deformation monitoring campaign
(Universidad de Chile, 2016)
La geomecánica y planificación minera son áreas de la minería a cielo abierto íntimamente relacionadas, ya que las restricciones geomecánicas limitan al diseño minero y, así, los planes mineros factibles. El diseño y los planes mineros han de...
Open pit geomechanics and mine planning are two closely related areas in the development of an open pit mine since geotechnical constrains limit the possible mine designs and, thus, the feasible mine plans. Mine designs and plans have to push the limits of what rock mass geomechanics allow to assure competitive mine operations, while maintaining acceptable levels of risk to operations and personnel. Therefore, geotechnical monitoring programs are required to acquire good quality data to be used as input for mine design. However, the relation between geomechanics and mine planning does not extend to monitoring programs design and implementation. Generally, surface deformation monitoring programs are designed after the project is in operation and signs of slope instability have been identified on the surface. Subsurface deformation monitoring can alert about developing failures weeks before any sign of instability is noted on the surface. Therefore, subsurface deformation monitoring campaigns should be designed along the mine planning process and considering the mine s design to install geotechnical instrumentation prior to the construction of the slopes. This methodology would allow to register the rock mass relaxation process as construction progresses and to acquire more comprehensive data about rock mass behaviour, in advanced of surface monitoring, towards future slope design optimization and adoption of remedial measurements to avoid failure. In this thesis, a series of subsurface deformation monitoring campaign were designed using In-Place Inclinometers, ShapeAccelArrays and Networked Smart Markers as monitoring devices. All options were applied to a theoretical open pit developed as part of this work. The campaigns were compared in terms of cost, quantity and quality of gathered data. The results showed that the campaign using NSMs installed every 2 meters was the most cost-efficient option as it represented: (1) the lowest cost per unit of gathered data (US$57.21), (2) five times longer lifespan, which allowed to gather twofold the amount of data compared with the next best option, (3) be financing of the campaign through steepening of the slopes by 2° and (4) increase in project s original NPV by 3.2%....
Open pit geomechanics and mine planning are two closely related areas in the development of an open pit mine since geotechnical constrains limit the possible mine designs and, thus, the feasible mine plans. Mine designs and plans have to push the limits of what rock mass geomechanics allow to assure competitive mine operations, while maintaining acceptable levels of risk to operations and personnel. Therefore, geotechnical monitoring programs are required to acquire good quality data to be used as input for mine design. However, the relation between geomechanics and mine planning does not extend to monitoring programs design and implementation. Generally, surface deformation monitoring programs are designed after the project is in operation and signs of slope instability have been identified on the surface. Subsurface deformation monitoring can alert about developing failures weeks before any sign of instability is noted on the surface. Therefore, subsurface deformation monitoring campaigns should be designed along the mine planning process and considering the mine s design to install geotechnical instrumentation prior to the construction of the slopes. This methodology would allow to register the rock mass relaxation process as construction progresses and to acquire more comprehensive data about rock mass behaviour, in advanced of surface monitoring, towards future slope design optimization and adoption of remedial measurements to avoid failure. In this thesis, a series of subsurface deformation monitoring campaign were designed using In-Place Inclinometers, ShapeAccelArrays and Networked Smart Markers as monitoring devices. All options were applied to a theoretical open pit developed as part of this work. The campaigns were compared in terms of cost, quantity and quality of gathered data. The results showed that the campaign using NSMs installed every 2 meters was the most cost-efficient option as it represented: (1) the lowest cost per unit of gathered data (US$57.21), (2) five times longer lifespan, which allowed to gather twofold the amount of data compared with the next best option, (3) be financing of the campaign through steepening of the slopes by 2° and (4) increase in project s original NPV by 3.2%....
Insights on the holocene climate of southernmost South America from paleoglacier reconstructions in Patagonia and Tierra del Fuego (46°-55°S)
(Universidad de Chile, 2019)
AND TIERRA DEL FUEGO (46°-55°S)
TESIS PARA OPTAR AL GRADO DE DOCTOR EN
CIENCIAS MENCIÓN GEOLOGÍA
SCOTT ANDREW, REYNHOUT
PROFESOR GUÍA:
MAISA ROJAS CORRADI
MIEMBROS DE LA COMISIÓN:
VALENTINA FLORES AQUEVEQUE
MICHAEL KAPLAN...
ESTEBAN SAGREDO TAPIA GABRIEL VARGAS EASTON SANTIAGO DE CHILE 2019 RESUMEN DE LA TESIS PARA OPTAR AL GRADO DE: Doctor en Ciencias, mención Geología POR: Scott Andrew Reynhout Reynhout FECHA: 03/09/2019 PROFESOR GUIA: Maisa Rojas Corradi...
ESTEBAN SAGREDO TAPIA GABRIEL VARGAS EASTON SANTIAGO DE CHILE 2019 RESUMEN DE LA TESIS PARA OPTAR AL GRADO DE: Doctor en Ciencias, mención Geología POR: Scott Andrew Reynhout Reynhout FECHA: 03/09/2019 PROFESOR GUIA: Maisa Rojas Corradi...
Space telescope and optical reverberation mapping project. III optical continuum emission and broadband time delays in ngc 5548
(IOP Publisihing, 2016)
, College Park, MD 20742-2421, USA
35 Astrophysics Science Division, NASA Goddard Space Flight Center, Greenbelt, MD 20771, USA
36 Instituto de Astrofísica de Canarias, E-38200 La Laguna, Tenerife, Spain
37 Departamento de Astrofísica, Universidad de La...
Laguna, E-38206 La Laguna, Tenerife, Spain 38 Gran Telescopio Canarias (GRANTECAN), E-38205 San Cristóbal de La Laguna, Tenerife, Spain 39 Spectral Sciences Inc., 4 Fourth Ave., Burlington, MA 01803, USA 40 Eureka Scientific Inc., 2452 Delmer St., Suite...
Laguna, E-38206 La Laguna, Tenerife, Spain 38 Gran Telescopio Canarias (GRANTECAN), E-38205 San Cristóbal de La Laguna, Tenerife, Spain 39 Spectral Sciences Inc., 4 Fourth Ave., Burlington, MA 01803, USA 40 Eureka Scientific Inc., 2452 Delmer St., Suite...
Medicinal chemistry targeting mitochondria: From new vehicles and pharmacophore groups to old drugs with mitochondrial activity
(MDPI, 2020)
de Chile, Olivos 943,
Santiago 8380544, Chile; jvfaundez@uc.cl
* Correspondence: jsandovalj@u.uchile.cl; Tel.: +56-2-29781730 or +56-2-29781718
† These authors contributed equally to the manuscript.
Received: 21 October 2020; Accepted: 12 November...
) H446 TRAMP cells ↓bcl‐2 ↓ ∆ψm ↓ Cell Viability [62,63] HeLa and MDA‐ MB‐231 ↑ ROS; ↓ GSH ↓ OXPHOS ↓Proliferation ↑ Mitophagy [64] Epigallocatechin Gallate (EGCG) (Catechin) Hep2 ↓bcl‐2; ↑ Bax ↓ ∆ψm [65] MIA PaCa‐2 and SMMC...
) H446 TRAMP cells ↓bcl‐2 ↓ ∆ψm ↓ Cell Viability [62,63] HeLa and MDA‐ MB‐231 ↑ ROS; ↓ GSH ↓ OXPHOS ↓Proliferation ↑ Mitophagy [64] Epigallocatechin Gallate (EGCG) (Catechin) Hep2 ↓bcl‐2; ↑ Bax ↓ ∆ψm [65] MIA PaCa‐2 and SMMC...
Phonetic analysis of consonantal groups in the boundaries of words and in word final position produced by ESL students in the English language and literature programme at Universidad de Chile
(Universidad de Chile, 2016)
’ which was criticized by Daniel
Jones (1952). In Mounin’s Diccionario de la Linguistica (1982) , he points that “it is
generally referred to juncture when in a word there is a boundary of moneme or
17
morpheme. This phenomenon is similar...
between / / and / / Vivanco C. and Vivanco H. (1993) in their arcticle “Algunas consideraciones acerca de la juntura fonética” in Taller de letras, state that the type of juncture influences the pronunciation of segments joined or separated by it. Let...
between / / and / / Vivanco C. and Vivanco H. (1993) in their arcticle “Algunas consideraciones acerca de la juntura fonética” in Taller de letras, state that the type of juncture influences the pronunciation of segments joined or separated by it. Let...
The Nuclear Near-Infrared Spectral Properties of Nearby Galaxies
(2015-03)
, Porto Alegre 91501-970, RS, Brazil
5 Instituto de Astrofísica de Canarias, Calle Vía Láctea, s/n, E-38205, La Laguna, Tenerife, Spain
6 Departamento de Astrofísica, Universidad de La Laguna, E-38205, La Laguna, Tenerife, Spain
7 Kavli Institute...
of Physics, 3601 Pacific Avenue, Stockton, CA 95211, USA 11 Instituto de Física de Cantabria, CSIC-UC, E-39005 Santander, Spain 12 Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago, Chile 13 Department of Physics and Astronomy...
of Physics, 3601 Pacific Avenue, Stockton, CA 95211, USA 11 Instituto de Física de Cantabria, CSIC-UC, E-39005 Santander, Spain 12 Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago, Chile 13 Department of Physics and Astronomy...