Browsing by Title Facultad de Medicina
Now showing items 10602-10621 of 12961
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(Hindawi, 2016)Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases, the maternal plasma cholesterol level increases to above this physiological range, leading to maternal ...
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(Bentham Science, 2015)Estradiol (E-2) is a steroid hormone whose physiological actions are mainly mediated by its interaction with intracellular estrogen receptors (ER) leading to modification on the mRNA and protein synthesis in its target ...
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(Elsevier, 2021)Background: During the initial COVID-19 outbreak, organizational changes were required to ensure adequate staffing in healthcare facilities. The extent to which organizational changes impacted the mental wellbeing ...
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(PeerJ, 2022)Background: It has been well established that proprioception plays a decisive role in shoulder stability and sport performance. Notwithstanding, there is a lack of clear association between active joint position sense ...
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(2004)Gestational diabetes is associated with increased L-arginine transport and nitric oxide (NO) synthesis, and reduced adenosine transport in human umbilical vein endothelial cells (HUVEC). Adenosine increases endothelial ...
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(Sociedad Argentina de Cardiologia, 2014)
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(Elsevier, 2015)© 2015 Elsevier B.V. Connexin hemichannels are regulated under physiological and pathological conditions. Metabolic inhibition, a model of ischemia, promotes surface hemichannel activation associated, in part, with increased ...
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(Frontiers Media, 2020)Oral squamous cell carcinoma, the most common type of oral cancer, affects more than 275,000 people per year worldwide. Oral squamous cell carcinoma is very aggressive, as most patients die after 3 to 5 years post-diagnosis. ...
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(2007)Background: Topical and systemic steroids are the first line of treatment of non infectious inflammatory ocular disease. Immunosuppresants are reserved as a second line treatment. Aim: To evaluate the role of Azathioprine ...
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(MDPI, 2020)Epstein-Barr virus is a ubiquitous persistent virus, which is involved in the development of some human cancers. A licensed vaccine to prevent Epstein-Barr virus infection is lacking. BamHI-A rightward frame 1 is a viral ...
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(Biomed Central, 2018)Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses ...
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(Universidad de Chile, 2021)Familial Alzheimer’s disease (FAD) is characterized by autosomal-dominant heritability and early onset. Mutations in the gene encoding presenilin-1 (PS1) are found in approximately 80% of cases of FAD. The etiology of ...
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(Frontiers Media, 2020)Cancer is a significant medical issue, being one of the main causes of mortality around the world. The therapies for this pathology depend on the stage in which the cancer is found, but it is usually diagnosed at an advanced ...
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(Universidad de Chile, 2018)Alteraciones en la homeostasis del retículo endoplasmático (RE) promueven la acumulación de proteínas mal plegadas en su lumen, una condición celular denominada estrés de RE. La adaptación al estrés de RE depende de la ...
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(Royal Society of Chemistry, 2020)Ultraviolet B (UVB) radiation induces autophagy responses, which play a role in the regulation of the oncogenic processes of irradiated cells. However, the mechanism of autophagy responses post-UVB irradiation remains to ...
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(2008)Cytochrome P450 enzymes are very important to metabolize anti-carcinogenic agents. Therefore, understanding the role of these enzymes and their allele variants in the bioactivation or detoxification of drugs could greatiy ...
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(International Institute of Anticancer Research, 2014)Aim: To assess the role of pro- and anti-inflammatory polymorphisms in gastric cancer susceptibility. Patients and Methods: We genotyped 12 polymorphisms in eight cytokine genes (Interleukin-1β-IL1B-, IL8, IL17A, IL17F, ...
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(Frontiers Media, 2015)The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
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Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases (Elsevier, 2015)Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags). Furthermore, an imbalance in the activating/inhibitory ...
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(Elsevier, 2018)Objective: The aim of this study was to evaluate the contribution of tocopherols present in Rosa mosqueta oil (RM) in the prevention of high-fat diet (HFD)-induced alterations. Methods: Male C57 BL/6 J mice (n = 9/group) ...
