Browsing by Title Facultad de Medicina

Now showing items 11529-11548 of 12946

    • Systemic lupus erythematosus impairs memory cognitive tests not affected by depression 
      Calderón, J.; Flores P., Jorge; Babul, M.; Aguirre, J. M.; Slachevsky Chonchol, Andrea; Padilla, O.; Scoriels, L.; Henríquez, C.; Cárcamo, C.; Bravo-Zehnder, M.; González, A.; Massardo, L. (SAGE Publications Ltd, 2014)
      Objective: Our aim was to assess the contribution of depression to cognitive impairment in patients with systemic lupus erythematosus (SLE). Methods: Clinical features, education, age, and Hospital Anxiety and Depression ...
    • Systemic oxidative stress and endothelial dysfunction is associated with an attenuated acute vascular ... 
      Gabrielli, Luigi; Castro, Pablo F.; Godoy, Ivan; Mellado, Rosemarie; Bourge, Robert C.; Alcaíno Gálvez, Hernán Alejandro; Chiong Lay, Mario; Greig, Douglas; Verdejo, Hugo; Navarro, Mario; Lopez, Rafael; Toro, Barbra; Quiroga, Clara; Díaz Araya, Guillermo; Lavandero González, Sergio; Garcia, Lo (2011)
      Background: Systemic endothelial dysfunction and increased oxidative stress have been observed in pulmonary arterial hypertension (PAH). We evaluate whether oxidative stress and endothelial dysfunction are associated with ...
    • Systemic sclerosis patients present alterations in the expression of molecules involved in B-cell regulation 
      Soto, Lilian; Ferrier, Ashley; Aravena Madariaga, Octavio; Fonseca, Elianet; Berendsen, Jorge; Biere, Andrea; Bueno, Daniel; Ramos, Verónica; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (Frontiers Media, 2015)
      The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this ...
    • Systemic synergism between codeine and morphine in three pain models in mice 
      Miranda, Hugo F.; Noriega, Viviana; Zepeda, Ramiro J.; Sierralta, Fernando; Prieto, Juan C. (Elsevier B.V., 2013)
      Background: The combination of two analgesic agents offers advantages in pain treatment. Codeine and morphine analgesia is due to activation of opioid receptor subtypes. Methods: This study, performed in mice using ...
    • Systemic toxocariasis in the adult patient Toxocariasis sistémica en el paciente adulto. 
      Rugiero,; Cabrera, Pablo; Ducach,; Noemi,; Viovy, (1995)
      We report a retrospective review of eight patients (one male), aged 19 to 31 years old, with systemic toxocariasis (visceral larva migrans), seen at the Salvador Hospital of Santiago. Four cases had heart involvement, three ...
    • Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation 
      Verdejo, Hugo; Roldán, Juan; García Nannig, Lorena; Del Campo, Andrea; Becerra, Elia; Chiong Lay, Mario; Mellado, Rosemarie; Garcia, Amalia; Zalaquett Sepúlveda, Ricardo; Braun, Sandra; Garayar, Bernardita; Gonzalez, Sergio; Lavandero González, Sergio; Corbalán, Ramón (2011)
      Background: Post-operative atrial fibrillation occurs in 30% of patients after on-pump heart surgery and is associated to elevated inflammatory markers. We have evaluated if the systemic biomarkers of inflammation and ...
    • Systemic vasculitis associated with Fasciola hepatica infection 
      Llanos, Carolina; Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Gallegos, I.; Valenzuela Letelier, Omar; Verdaguer, J.; Cuchacovich Turteltaub, Miguel (TAYLOR & FRANCIS AS, 2006-04)
      We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. ...
    • T cell exosome–derived miR-142-3p impairs glandular cell function in Sjögren’s syndrome 
      Cortes Troncoso, Juan; Jang, Shyh-Ing; Pérez, Paola; Hidalgo, Jorge; Ikeuchi, Tomoko; Greenwell-Wild, Teresa; Warner, Blake M.; Moutsopoulos, Niki M.; Alevizos, Ilias (The American Society for Clinical Investigation, 2020)
      Sjogren's syndrome (SS) is a systemic autoimmune disease that mainly affects exocrine salivary and lacrimal glands. Local inflammation in the glands is thought to trigger glandular dysfunction and symptoms of dryness. ...
    • T lymphocytes activated by persistent viral infection differentially modify the expression of metalloproteinases ... 
      Giraudon, Pascale; Szymocha, Raphaël; Buart, Stéphanie; Bernard, Arlette; Cartier Rovirosa, Luis; Belin, Marie Françoise; Akaoka, Hideo (American Association of Immunologists, 2000)
      Activation of T lymphocytes by human pathogens is a key step in the development of immune-mediated neurologic diseases. Because of their ability to invade the CNS and their increased secretion of proinflammatory cytokines, ...
    • t-butyl-4-hydroxyanisole as an inhibitor of tumor cell respiration 
      Fones, Elizabeth; Amigo, Hannelore; Gallegos, Kimie; Guerrero, Anibal; Ferreira, Jorge (1989)
      The effect of t-butyl-4-hydroxyanisole (BHA), a widely used food antioxidant additive, on the culture growth, oxygen consumption, and redox state of some electron carriers of intact TA3 and 786A ascites tumor cells has ...
    • t-Butyl-4-hydroxyanisole, a novel respiratory chain inhibitor. Effects on Trypanosoma cruzi epimastigotes 
      Aldunate, Jorge; Ferreira, Jorge; Letelier Muñoz, María Eugenia; Repetto Scaramelli, Yolanda; Morello Casté, Antonio (1986)
      t-Butyl-4-hydroxyanisole, an antioxidant food additive, inhibited the growth of Trypanosoma cruzi by almost 100% at 0.5 mM concentration. This compound inhibited 70% of oxygen consumption of epimastigotes. The redox level ...
    • T-cell receptor variable alpha (TCRAV) polymorphisms in European, Chinese, South American, AfroCaribbean, ... 
      Ibberson, Mark R.; Copier, John P.; Llop Romero, Elena; Navarrete, Cristina; Hill, Adrian V.S.; Cruickshank, J. Kennedy; So, Alex K.L. (1998)
      Interactions involving the T-cell receptor (TCR) and major histocompatibility complex (MHC) are fundamental to the generation of a specific immune response. The study of interpopulation differences in TCR genes may identify ...
    • T-kininogen can either induce or inhibit proliferation in Balb/c 3T3 fibroblasts, depending on the route ... 
      Aravena, Mauricio; Pérez, C.; Pérez, V.; Acuña Castillo, Claudio; Gómez, Christian; Leiva Salcedo, Elías; Nishimura, Sumiyo; Sabaj, B.; Walter, Robin Ann (ELSEVIER SCI IRELAND LTD, 2005-03)
      T-kininogen (T-KG) is a precursor of T-kinin, the most abundant kinin in rat serum, and also acts as a strong and specific cysteine proteinase inhibitor. Its expression is strongly induced during aging in rats, and expression ...
    • T-kininogen induces endothelial cell proliferation 
      Pérez, Viviana; Leiva Salcedo, Elías; Acuña Castillo, Claudio; Aravena, Mauricio; Gómez, Christian; Sabaj Diez, Valeria; Colombo, Alicia; Nishimura, Sumiyo; Pérez Núñez, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      Basal proliferation of endothelial cells increases with age, and this might play a role in the etiology of age-related vascular diseases, as well as angiogenesis. Serum kininogen levels increase during aging in rats and ...
    • T-kininogen inhibits kinin-mediated activation of ERK in endothelial cells 
      Leiva-Salcedo, Elias; Perez, Viviana; Acuña Castillo, Claudio; Walter, Robin Ann; Sierra, Felipe (Society of Biology of Chile, 2002)
      Serum levels of T-kininogen increase dramatically as rats approach the end of their lifespan. Stable expression of the protein in Balb/c 3T3 fibroblasts leads to a dramatic inhibition of cell proliferation, as well as ...
    • T-kininogen, a cystatin-like molecule, inhibits ERK-dependent lymphocyte proliferation 
      Acuña Castillo, Claudio; Aravena, Mauricio; Leiva Salcedo, Elías; Pérez, Viviana; Gómez, Christian; Sabaj Diez, Valeria; Nishimura, Sumiyo; Pérez Núñez, Claudio; Colombo, Alicia; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2005-12)
      Plasma levels of kininogens increase with age in both rats and humans. Kininogens are inhibitors of cysteine proteinases, and filarial cysteine proteinase inhibitors (cystatins) reduce the proliferation of T cells. We ...
    • T-kininogen: A biomarker of aging in fisher 344 rats with possible implications for the immune response 
      Acuña Castillo, Claudio; Leiva-Salcedo, Elias; Gómez, Christian R.; Pérez, Viviana; Li, Min; Torres, Claudio; Walter, Robin Ann; Murasko, Donna M.; Sierra, Felipe (Gerontological Society of America, 2006)
      T-kininogen (T-KG) is a reliable biomarker of aging in male Sprague-Dawley rats. Here we confirm, in a longitudinal study, a similar behavior in Fisher 344 rats of both sexes. In males, the increase in serum levels of T-KG ...
    • T-lymphocyte phenotype and function triggered by Aggregatibacter actinomycetemcomitans is serotype-dependent 
      Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Alvarez, C.; Monasterio, G.; Benítez, A.; Ciuchi, P.; Díaz, C.; Mardones, J.; Escobar, A.; Sanz, M.; Vernal Astudillo, Rolando (Blackwell Munksgaard, 2015)
      & Sons Ltd. Background and Objective: Based on lipopolysaccharide (LPS) antigenicity, different Aggregatibacter actinomycetemcomitans serotypes have been described. Serotype b strains have demonstrated a stronger capacity ...
    • T. cruzi DNA polymerase beta (Tcpol beta) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the ... 
      Maldonado Maldonado, Edio Luis; Rojas, Diego A.; Urbina, Fabiola; Solari Illescas, Aldo Gerónimo (Public Library Science, 2021)
      The unicellular protozoan Trypanosoma cruzi is the causing agent of Chagas disease which affects several millions of people around the world. The components of the cell signaling pathways in this parasite have not been ...
    • T. cruzi oligoC-tesT: A simplified and standardized polymerase chain reaction format for diagnosis of Chagas ... 
      Deborggraeve, Stijn; Coronado, Ximena; Solari Illescas, Aldo; Zulantay Alfaro, Inés; Apt Baruch, Werner; Mertens, Pascal; Laurent, Thierry; Leclipteux, Thierry; Stessens, Tim; Dujardin, Jean Claude; Herdewijn, Piet; Büscher, Philippe (2009)
      Background: PCR has evolved into one of the most promising tools for T. cruzi detection in the diagnosis and control of Chagas disease. However, general use of the technique is hampered by its complexity and the lack of ...