Browsing by Title Facultad de Medicina
Now showing items 12410-12429 of 12970
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(MDPI, 2020)The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been made in identifying novel members of the TRPM ...
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(Taylor & Francis, 2017)Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal death. This process has two components, a glutamate-dependent and a glutamate-independent mechanism. In the glutamate-independent ...
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(Wiley, 2019)Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐ dependent monovalent cation channel, which depolarizes the plasma cell membrane, thereby modulating Ca2+ influx across Ca2+‐permeable ...
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(2011)Altered expression of some members of the TRP ion channel superfamily has been associated with the development of pathologies like cancer. In particular, TRPM4 levels are reportedly elevated in diffuse large B-cell non-Hodgkin ...
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(Frontiers Media, 2021)TRPM4 is a non-selective cation channel activated by intracellular calcium and permeable to monovalent cations. This channel participates in the control of neuronal firing, neuronal plasticity, and neuronal death. TRPM4 ...
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(Public Library Science, 2015)Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations. TRPM4 is a ...
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(John Wiley, 2018)Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...
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(Nature Publishing Group, 2020)Acute kidney injury and endothelial hyperpermeability are main features observed during severe sepsis with low survival rate. Transient receptor potential melastatin 7 (TRPM7) calcium channel inhibition protects against ...
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(John Wiley and Sons Inc.P.O.Box 18667NewarkNJ 07191-8667, 2020)
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(1985)ABSTRACT— An evaluation of the information obtained by percutaneous liver biopsy performed with Travenol Tru‐cut® (“Tru‐cut”), Menghini's 1.9 and 1.6 needles, was done using cadavers. All needles used had a similar, low ...
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(Frontiers Media, 2020)Trypanosoma cruzi and Toxoplasma gondii are two parasites than can be transmitted from mother to child through the placenta. However, congenital transmission rates are low for T. cruzi and high for T. gondii. Infection ...
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(Springer Verlag, 2015)© 2015, The Author(s).There are currently no biomarkers to assess which patients with chronic indeterminate Chagas disease will develop heart disease and which will spend their entire life in this state. We hypothetize ...
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(Elsevier Ltd, 2014)Trypanosoma cruzi, the agent of Chagas' disease, the sixth neglected tropical disease worldwide, infects 10-12 million people in Latin America. Differently from T. cruzi epimastigotes, trypomastigotes are complement-resistant ...
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(Elsevier, 2014)Trypanosoma cruzi, the agent of Chagas’ disease, the sixth neglected tropical disease worldwide, infects10–12 million people in Latin America. Differently from T. cruzi epimastigotes, trypomastigotes arecomplement-resistant ...
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(Elsevier, 2011)In Trypanosoma cruzi, calreticulin (TcCRT) translocates from the endoplasmic reticulum (ER) to the area of flagellum emergence. We propose herein that the parasite uses this molecule to capture complement C1, in an ...
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(2009)Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There ...
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(Elsevier, 2020)Recombinant calreticulin from Trypanosoma cruzi (rTcCalr), the parasite responsible for Chagas' disease, binds to Canine Transmissible Venereal Tumor (CTVT) cells from primary cultures and to a canine mammary carcinoma ...
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(2013-03)Trypanosoma cruzi calreticulin (TcCRT) can hijack complement C1, mannan-binding lectin and ficolins from serum thus inhibiting the classical and lectin complement pathway activation respectively. To understand the in ...
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(Elsevier B.V., 2016)© 2016 Elsevier B.V. As part of a multi-site research program on the eco-epidemiology and control of Chagas disease in northern Chile, we sought to identify the Trypanosoma cruzi discrete typing units (DTUs) infecting rural ...
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(MARY ANN LIEBERT INC, 2012-03)Fifty-six Trypanosoma cruzi stocks from Chile and neighboring countries and different hosts, humans, and Triatoma infestans and Mepraia sp., vectors of domiciliary and natural environments were characterized by using three ...