Now showing items 12437-12456 of 12946

    • Henríquez, Juan P.; Cambiazo Ayala, Verónica; Maccioni Baraona, Ricardo (1996)
      The interaction of microtubule associated proteins (MAPs) with the microtubule system has been characterized in depth in neuronal cells from various mammalian species. These proteins interact with well-defined domains ...
    • Farías, Gustavo A.; Muñoz, Juan P.; Garrido, Jorge; Maccioni Baraona, Ricardo (2002)
      The intracellular polymerization of cytoskeletal proteins into their supramolecular assemblies raises many questions regarding the regulatory patterns that control this process. Binding experiments using the ELISA solid ...
    • Urzúa, Ulises; Owens, Garrison A.; Zhang, Gen Mu; Cherry, James M.; Sharp, John J.; Munroe, David J. (2010)
      Background: The link between reproductive life history and incidence of ovarian tumors is well known. Periods of reduced ovulations may confer protection against ovarian cancer. Using phenotypic data available for mouse, ...
    • Jaña, Fabián; Faini, Francesca; Lapier, Michel; Pavani, Mario; Kemmerling Weis, Ulrike; Morello Casté, Antonio; Maya Arango, Juan; Jara, José; Parra, Eduardo; Ferreira Parker, Jorge (Elsevier, 2013)
      Changes in mitochondrial ATP synthesis can affect the function of tumor cells due to the dependence of the first step of glycolysis on mitochondrial ATP. The oxidative phosphorylation (OXPHOS) system is responsible for ...
    • González, Fermín E.; Gleisner, Alejandra; Falcón Beas, Felipe; Osorio, Fabiola; López, Mercedes N.; Salazar Onfray, Flavio (Landes Bioscience, 2014)
      Autologous dendritic cells (DCs) loaded with tumor-associated antigens (TAAs) are a promising immunologicaltool for cancer therapy. These stimulate the antitumorresponse and immunological memory generation.Nevertheless, ...
    • Rojas Sepúlveda, D.; Gleisner, M. A.; Pereda, C.; López, M.; Salazar Onfray, Flavio (2016)
    • Gac Espinoza, Patricio; Cabané Toledo, Patricio; Franco S., Carmen; Amat Vidal, José; Rossi F., Ricardo; Huidobro G., Felipe; Carreño Toro, Laura; Covarrubias C., Patricio (SOC MEDICA SANTIAGO, 2008-02)
      Histiocytic necrotizing lymphadenitis (HNL), also known as Kikuchi's disease is a rare condition of unknown etiology Patients present with cervical lymph node enlargement fever and malaise. The diagnosis is made by excision ...
    • Labbé, Javier; Pumarino, Andrés; Valdivia, Gerardo; Ibarra, Julio; Merello, Lorenzo; Quiroz, Manuel (2014)
      Presentamos un caso de leiomiomatosis intravascular que se extiende a cavidades cardiacas derechas, siendo tratado mediante cirugía en un tiempo.
    • Labbé, Javier; Pumarino, Andrés; Valdivia, Gerardo; Ibarra, Julio; Merello, Lorenzo; Quiroz Flores, Manuel (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2014)
      Presentamos un caso de leiomiomatosis intravascular que se extiende a cavidades cardiacas derechas, siendo tratado mediante cirugía en un tiempo.
    • Rojas-Sepúlveda, Daniel; Tittarelli, Andrés; Gleisner, María Alejandra; Ávalos, Ignacio; Pereda, Cristián; Gallegos, Iván; González, Fermín Eduardo; López, Mercedes Natalia; Butte, Jean Michel; Roa, Juan; Fluxá, Paula; Salazar Onfray, Flavio (Springer Science and Business Media Deutschland GmbH, 2018)
      © 2018, The Author(s). Immunotherapy based on checkpoint blockers has proven survival benefits in patients with melanoma and other malignancies. Nevertheless, a significant proportion of treated patients remains refractory, ...
    • González Navarrete, Flor Cecilia; Eisner, Verónica; Morales, Priscilla; Castro, Olga; Pommer Téllez, Ricardo; Quiroga, Clara; Lavandero González, Sergio; Devoto, Luigi (2007)
      Background. The role of tumor necrosis factor-α (TNF-α) in granulosa luteal cell function and steroidogenesis is still controversial. Our aim was to examine the steroidogenic response, together with the simultaneous ...
    • Smith, P.C.; Guerrero, J.; Tobar, N.; Cáceres, M.; González, M. J.; Martínez, J. (2009)
      Background and Objectives: Membrane type 1-matrix metalloproteinase (MT1-MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In periodontal tissues, either cytokines or growth factors regulate the ...
    • Acuña Lawrence, Renato; Soto L., Patricio; Muñoz R., Vanessa; Acuña R., Javiera (2008)
      Objetivo: Las neoplasias de páncreas son muy infrecuentes, más aún en la edad pediátrica, y el tumorsólido pseudopapilar de páncreas corresponde alrededor del 1% de los tumores primarios de páncreas,caracterizándose por ...
    • Aretxabala, Xabier de; Rencoret, Guillermo; Maluenda G., Fernando; Fernández F., Carmen; Csendes Juhasz, Attila (2008)
      Se describe una paciente de 16 años portadora de un tumor solido pseudopapilar del páncreas. (TSP) La paciente fue referida a nuestro hospital por un cuadro de dolor abdominal y la existencia a la tomografía computada ...
    • Ávalos, Yenniffer; Canales, Jimena; Bravo Sagua, Roberto; Criollo Céspedes, Alfredo; Lavandero González, Sergio; Quest, Andrew F. G. (Hindawi, 2014)
      Autophagy is a highly regulated catabolic process that involves lysosomal degradation of proteins and organelles, mostly mitochondria, for the maintenance of cellular homeostasis and reduction of metabolic stress. Problems ...
    • González, G.; Baudrand, R.; Sepúlveda, M. F.; Vucetich, N.; Guarda, F. J.; Villanueva, P.; Contreras, O.; Villa, A.; Salech Morales, Felipe; Toro Cabrera, Luis; Michea Acevedo, Luis; Florenzano, P. (Springer, 2017)
      The majority of tumor-induced osteomalacia cases have been reported in the Northern Hemisphere and Asia. In this first series of South American patients, we show that the clinical presentation and sensitivity of plasmatic ...
    • Carvajal Hafemann, Carlos; Iturra U., Sebastián; Justiniano Peralta, Juan; Bustamante Zamorano, Marco; Contreras P., Juan Eduardo; Lombardi Solari, Juan; Capetillo Fuentes, María (2006)
      Gastrointestinal stromal tumors (GIST) are lesions whose diagnosis and treatment have varied in the last decade. We report a 76 year-old male with a history of eight episodes of upper gastrointestinal bleeding. A ...
    • Chávez S, Cristóbal; García C, Karen; Rojas N, Sergio; Barahona A, Luis; Naser G, Alfredo; Nazar S, Rodolfo (SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2020)
    • Braghetto Miranda, Italo; Parada, Francisco; Cardemil Herrera, Gonzalo; Csendes Juhasz, Attila; Fernández, Eduardo; Korn Bruzzone, Owen; Ramírez Fernández, Marcos; Carreño Toro, Laura; Smok Sahid, Gladys; Molina, Juan Carlos; Lembach Jahnsen, Hanns (2007)
      Background Gastrointestinal stromal tumors (GIST) are the most common mesenchymatous tumors of the digestive tract. The pathological diagnosis is based on microscopy and immunohistochemistry. Aim To review the experience ...
    • Aretxabala, Xabier de; Roa, Iván; León, Jorge; Maluenda, Fernando (SOC MEDICA SANTIAGO, 2008-09)