Now showing items 1283-1302 of 12970

    • Benrick, Anna; Kokosar, Milana; Hu, Min; Larsson, Martin; Maliqueo Yevilao, Manuel; Marcondes, Rodrigo Rodrigues; Soligo, Marzia; Protto, Virginia; Jerlhag, Elisabet; Sazonova, Antonina; Behre, Carl Johan; Højlund, Kurt; Thorén, Peter; Stener-Victorin, Elisabet (FASEB, 2017)
      © FASEB A single bout of low-frequency electroacupuncture (EA) causing muscle contractions increases wholebody glucose uptake in insulin-resistant rats.We explored the underlyingmechanism of this finding andwhether it can ...
    • Gajardo Cortez, Abraham; Madariaga, Samuel; Maldonado Arbogast, Pedro (Churchill Livingstone, 2019)
      Background: Cardiovascular risk (CVR) biomarkers are of increasing interest because of their potential utility in management of cardiovascular diseases. The activity of the autonomic nervous system (ANS) is known to be ...
    • Moreno, Ximena; Huerta, Martín; Albala Brevis, Cecilia (Elsevier, 2014)
      Objetivo: Explorar la asociación entre autopercepción de salud general negativa y mortalidad en adultos mayores. Método: Revisión sistemática cuyos criterios de inclusión fueron estudios longitudinales, evaluación de la ...
    • González, Alexis E.; Muñoz, Vanessa C.; Cavieres, Viviana A.; Bustamante, Hianara A.; Cornejo, Víctor Hugo; Januário, Yunan C.; González, Ibeth; Hetz Flores, Claudio; Dasilva, Luis L.; Rojas-Fernández, Alejandro; Hay, Ronald T.; Mardones, Gonzalo A.; Burgos, Patricia V. (FASEB, 2017)
      © FASEB. Brain regions affected by Alzheimer disease (AD) displaywell-recognized early neuropathologic features in the endolysosomal and autophagy systems of neurons, including enlargement of endosomal compartments, ...
    • Peña Oyarzún, Daniel; Bravo Sagua, Roberto; Díaz Vega, Alexis; Aleman, Larissa; Chiong Lay, Mario; García Nannig, Lorena; Bambs, Claudia; Troncoso, Rodrigo; Cifuentes, Mariana; Morselli, Eugenia; Ferreccio, Catterina; Quest, Andrew F. G.; Criollo Céspedes, Alfredo; Lavandero González, Sergio (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Non-communicable diseases (NCDs), also known as chronic diseases, are long-lasting conditions that affect millions of people around the world. Different factors contribute to their genesis and progression; ...
    • Nemchenko, Andriy; Chiong Lay, Mario; Turer, Aslan; Lavandero González, Sergio; Hill, Joseph A. (2011)
      The epidemic of heart failure continues apace, and development of novel therapies with clinical efficacy has lagged. Now, important insights into the molecular circuitry of cardiovascular autophagy have raised the prospect ...
    • Hazari, Younis M.; Bravo San Pedro, José Manuel; Hetz Flores, Claudio; Galluzzi, Lorenzo; Kroemer, Guido (Elsevier, 2020)
      Autophagy is an evolutionarily ancient process whereby eukaryotic cells eliminate disposable or potentially dangerous cytoplasmic material, to support bioenergetic metabolism and adapt to stress. Accumulating evidence ...
    • Mattar, Pamela; Bravo Sagua, Roberto; Tobar, Nicolás; Fuentes, Cecilia; Troncoso, Rodrigo; Breitwieser, Gerda; Lavandero González, Sergio; Cifuentes, Mariana (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Obesity is a major current public health problem worldwide due to the severe co-morbid conditions that this disease entails. The development of obesity-related cardiometabolic disorders is in direct ...
    • Matus, Soledad; Bosco, Daryl A.; Hetz Flores, Claudio (Elsevier, 2014)
      Mutations in fused in sarcoma and/or translocated in liposarcoma (FUS, TLS or FUS) are linked to familial cases of amyotrophic lateral sclerosis (ALS). Mutant FUS selectively accumulates into discrete cytosolic structures ...
    • Paris Pizarro, Irmgard; Muñoz, Patricia; Huenchuguala, Sandro; Couve, Eduardo; Sanders, Laurie H.; Greenamyre, John Timothy; Caviedes, Pablo; Segura Aguilar, Juan (2011)
      Aminochrome, the precursor of neuromelanin, has been proposed to be involved in the neurodegeneration neuromelanincontaining dopaminergic neurons in Parkinson's disease. We aimed to study the mechanism of aminochrome-dependent ...
    • Silva, Victor D.A.; Urriola Cuevas, Carlos; Muñoz, Patricia; Villa, Monica; Ahumada-Castro, Ulises; Huenchuguala, Sandro; Dos Santos, Cleonice C.; De Araujo, Fillipe M.; Ferreira, Rafael; Da Silva, Vanessa B.; Silva, Juliana H.C.; Soares, Érica N.; Velozo, Eudes S.; Segura Aguilar, Juan (Academia Brasileira de Ciencias, 2017)
      © 2017, Academia Brasileira de Ciencias. All rights reserved. Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be ...
    • Budini, Mauricio; Jacob, Germaine; Jedlicki, Ana; Pérez, Carolina; Allende, Catherine C.; Allende, Jorge E. (2009)
      CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...
    • Varela,; Maturana, Daniel; Uribe, (1974)
      We formulate the organization of living organisms through the characterization of the class of autopoietic systems to which living things belong. This general characterization is seen at work in a computer simulated model ...
    • Crain, Barbara J.; Valdes, Fernando; Chang, Kwen Jen; McNamara, James O. (1985)
      The benzomorphan subpopulation of opiate binding sites was labeled by [3H]diprenorphine in the presence of unlabeled ligands selected to quench μ and δ opiate binding sites. The distribution of benzomorphan binding sites ...
    • Fernandez, Virginia; Bravo, Roberto (1974)
      The histogenetic development of the archi, paleo and neocortex of the rabbit was studied using autoradiographic techniques. The analysis is based upon a series of 54 embryos and newborn rabbits, whose mothers were injected ...
    • Tchernitchin Varlamov, Andrés (1967)
      (6,7-3H) oestradiol-17β incorporation by the rat uterus has been studied using autoradiography. The cytoplasm and/or the cellular membrane of uterine eosinophilic cells seems to incorporate oestradiol in a much greater ...
    • Andresen, Max; Corrales, Raúl; Gallardo, Jorge; Noriega, Viviana; Sánchez, Eliana; Weinstein, Caroline (Sociedad Médica de Santiago, 2020)
    • Flores, Claudio; Conte Lanza, Guillermo; Fardella, Patricia; Araos, Daniel; Alfaro Lucero, Jorge; Aravena Rodríguez, Paola Carolina; González Gómez, Néstor; Larrondo Lillo, Milton (SOC MEDICA SANTIAGO, 2005-08)
      Background: Multiple myeloma is rarely curable. Advances in high dose chemotherapy and stem cell transplantation have improved overall survival and event-free disease periods, but relapses are inevitable. Aim: To report ...
    • Valenzuela, Manuel A.; Bastías, Lorena; Montenegro, Ivan; Werner, Enrique; Madrid, Alejandro; Godoy, Patricio; Parraga, Mario; Villena, Joan (Hindawi Ltd, 2018)
      Antioxidants are known to be beneficial to health. This paper evaluates the potential chemopreventive and anticancer properties of phenolic compounds present in grape juice extracts (GJE) from Autumn Royal and Ribier ...