Browsing by Title Facultad de Medicina

Now showing items 8198-8217 of 12938

    • NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells 
      Espinosa, Alejandra; García, Alejandra; Härtel, Steffen; Hidalgo Tapia, María Cecilia; Jaimovich Pérez, Enrique (2009)
      Skeletal muscle is one of the main physiological targets of insulin, a hormone that triggers a complex signaling cascade and that enhances the production of reactive oxygen species (ROS) in different cell types. ROS, ...
    • Nail-patella syndrome associated with monoclonal gammopathy. Review regarding a case Síndrome uña-rótula ... 
      Panace,; Mocarquer,; Anguita,; Cortés, (1993)
      A 54 years old female with significant impairment of renal function is presented. On physical examination, the presence of dystrophic nails, elbow dysplasia and prominent iliac horns. Familial study showed similar nail and ...
    • Naked DNA immunization as an approach to target the generic tumor antigen survivin induces humoral and ... 
      Lladser, Álvaro; Párraga, Mario; Quevedo, Licarallén; Molina, Maria Carmen; Silva, Soledad; Ferreira, Arturo; Billetta, Rosario; Quest, Andrew F. G. (Elsevier GmbH, 2006)
      Survivin, a 16.5 kDa tumor associated antigen, is the smallest member of the inhibitor of apoptosis family that is abundantly expressed during development but essentially absent in normal adult tissues. Interestingly, ...
    • Naltrexone effects on insulin sensitivity and insulin secretion in hyperandrogenic women 
      Sir Petermann, Teresa; López, G.; Castillo, T.; Calvillán,; Rabenbauer, B.; Wildt, L. (1998)
      A total of 12 women (24.2 ± 1.6 years old, BMI 36.7 ± 1.5 Kg/m2) with hyperandrogenism (HA) and with normal glucose tolerance test were studied to evaluate the involvement of endogenous opioids in the pathophysiology of ...
    • Nanoparticle-mediated angiotensin-(1-9) drug delivery for the treatment of cardiac hypertrophy 
      Sepúlveda Rivas, Sabrina; Leal, Matías S.; Pedrozo Cibils, Zully Rocío Evangelina; Kogan, Marcelo Javier; Ocaranza Jeraldino, María Paz Alejandra; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced ...
    • Nanotechnology-based drug delivery strategies to repair the mitochondrial function in neuroinflammatory and ... 
      González, Luis F.; Bevilacqua Corredoira, Lorenzo Emilio; Naves Pichuante, Rodrigo Antonio (MDPI, 2021)
      Mitochondria are vital organelles in eukaryotic cells that control diverse physiological processes related to energy production, calcium homeostasis, the generation of reactive oxygen species, and cell death. Several studies ...
    • Narrative discourse in first grade children with specific language impairment (SLI) Discurso narrativo en ... 
      Coloma, Carmen Julia (2014)
      Narrative production in children with Specific Language Impairment (SLI) may be poor, and that deficit could impact their school performance. There is scarce information regarding the features of the narrative deficit in ...
    • Nasal carriage of Streptococcus pneumoniae in elderly subjects according to vaccination status 
      Altuzarra, Rogelio; Valenzuela Bravo, María Teresa; Trucco Aray, Olivia; Inostroza, Jaime; Granata Sasson, Paulo; Fleiderman, José (2007)
      Background: S pneunaoniae is the main cause of community-acquired pneumonia in the elderly,. group that concentrates 95% of deaths. Aim: To assess the prevalence of nasal carriage of S pneumoniae in institutionalized elderly ...
    • Nasal natural killer/T-cell lymphoma and its association with type "i"/Xhol loss strain Epstein-Barr virus in Chile 
      Cabrera Contreras, María Elena; Eizuru, Yoshito; Itoh, T.; Koriyama, Chihaya; Tashiro, Y.; Ding, Shan; Rey, Sergio; Akiba, Suminori; Corvalán, Alejandro (2007)
      Background: Nasal T/natural killer (NK)-cell lymphoma is an aggressive type of non-Hodking's lymphoma associated with Epstein-Barr virus (EBV) and striking geographical variations worldwide. Aim: To characterise nasal ...
    • Nasal profile assessment using geometric morphometrics in a sample of Chilean population. Clinical and ... 
      López, Bernarda; Toro, Viviana; Schilling, Alejandro; Galdames, Iván Suazo (Universidad de la Frontera, 2012)
      The search of morphological patterns of nasal profile using traditional morphometrics has been the goal of several studies aiming to orient therapeutical planning and forensic techniques such as facial reconstruction. The ...
    • Nasal reconstruction with a forehead flap in children younger than 10 years of age 
      Giugliano, Carlos; Andrades Cvitanic, Patricio; Benítez Seguel, Susana Alejandra (2004)
      Nasal reconstruction has been analyzed extensively in adults but not in children. The purpose of this article is to review the authors' experience with the forehead flap for nasal reconstruction in 10 children under the ...
    • National Health Insurance: A conceptual framework from conflicting typologies 
      Cuadrado, Cristóbal; Crispi, Francisca; Libuy, Matías; Marchildon, Gregory; Cid, Camilo (Elsevier Ireland Ltd, 2019)
      In the path to universal health coverage, policymakers discuss different alternative health system's financing schemes. Classical typologies have been posited, including models such as National Health Service, Social Health ...
    • National Health Policy Reform for Primary Care in Chile: A Qualitative analysis of the health program documents 
      Domínguez Cancino, Karen A.; Palmieri, Patrick A.; Martínez Gutiérrez, María Soledad (SAGE, 2020)
      Introduction: Chilean policy makers reformed the national health policy for primary health care (PHC), shifting from the traditional biomedical model to the integral family and community health model with a biopsychosocial ...
    • National Trend in Laparoscopic Gastrectomy for Gastric Cancer: Analysis of the National Register in Chile 
      Norero, Enrique; Funke, Ricardo; Garcia, Carlos; Fernandez, Jose Ignacio; Lanzarini, Enrique; Rodriguez, Jorge; Ceroni, Marco; Crovari, Fernando; Pinto, Gerardo; Musleh, Maher; Gonzalez, Paulina (S. Karger AG, 2018)
      © 2018 S. Karger AG, Basel.Introduction: The laparoscopic approach for the treatment of gastric cancer has many advantages. However, outside Asia there are few large case series. Aim: To evaluate postoperative morbidity, ...
    • Native American gene flow into Polynesia predating Easter Island settlement 
      Ioannidis, Alexander G.; Blanco Portillo, Javier; Sandoval, Karla; Hagelberg, Erika; Miquel-Poblete, Juan Francisco; Moreno Mayar, J. Víctor; Rodríguez Rodríguez, Juan Esteban; Auckland, Kathryn; Parks, Tom; Robson, Kathryn; Hill, Adrian V. S.; Ávila Arcos, María C.; Sockell, Alexandra; Homburger, Julian R; Wojcik, Genevieve L.; Barnes, Kathleen C.; Herrera, Luisa M.; Berríos, Soledad; Acuña, Mónica; Llop, Elena; Eng, Celeste; Huntsman, Scott; Burchard, Esteban G.; Gignoux, Christopher R.; Cifuentes, Lucía O.; Verdugo Salgado, Ricardo; Moraga Vergara, Mauricio; Mentzer, Alexander J.; Bustamante, Carlos D.; Moreno Estrada, Andrés (Nature, 2020)
      The possibility of voyaging contact between prehistoric Polynesian and Native American populations has long intrigued researchers. Proponents have pointed to the existence of New World crops, such as the sweet potato and ...
    • Native strains of Trichoderma from northern Chile: Adaptive tolerance in boric saline soils 
      Salvatierra-Martínez, Ricardo; Sepúlveda-Chavera, Germán; Huanca-Mamani, Wilson; Rodríguez-Molina, Manuel (Interciencia Association, 2015)
      © 2015, Interciencia Association. All rights reserved. Commercial strains of Trichoderma show erratic results on soil diseases in northern Chile. Tolerance and antagonistic capacity were assessed in 10 isolates of native ...
    • Natural and synthetic naphthoquinones active against Trypanosoma cruzi: An initial step towards new drugs ... 
      Salas, Cristian O.; Faúndez, Mario; Morello Casté, Antonio; Maya Arango, Juan; Tapia, Ricardo A. (2011)
      Chagas disease is one of the most important endemic diseases in Latin America, caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, nifurtimox and benznidazole, are toxic and present severe side ...
    • Natural history of diabetic retinopathy in a retrospective cohort of type 1 diabetics Historia natural de ... 
      Verdaguer, Juan; Zanolli, Mario; Sepúlveda, Gonzalo; García de los Ríos, Manuel; Domínguez, Angélica (2009)
      Background: Diabetic retinopathy is one of the most common causes of blindness among adults. Aim: To report the natural history of diabetic retinopathy among Chilean patients with type 1 diabetes followed for a mean of 18 ...
    • Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: ... 
      Castinetti, Frederic; Waguespack, Steven G.; Machens, Andreas; Uchino, Shinya; Hasse-Lazar, Kornelia; Sanso, Gabriella; Else, Tobias; Dvorakova, Sarka; Qi, Xiao Ping; Elisei, Rossella; Maia, Ana Luisa; Glod, John; Lourenço, Delmar Muniz; Valdes, Nuria; Mathiesen, Jes (Lancet Publishing Group, 2019)
      © 2019 Elsevier LtdBackground: Multiple endocrine neoplasia type 2B is a rare syndrome caused mainly by Met918Thr germline RET mutation, and characterised by medullary thyroid carcinoma, phaeochromocytoma, and extra-endocrine ...
    • Natural killer cell activity in patients with septic shock 
      Maturana, Patricio; Puente, Javier; Miranda, Dante; Sepulveda, Cecilia; Wolf, Marion E.; Mosnaim, Aron D. (1991)
      Natural killer cell activity (NKCA) was studied in a group of patients (n = 11) with septic shock. When compared with controls (n = 10), these individuals showed a statistically significant reduction in NKCA at each of the ...