Browsing by Author "Hayman, Michael J."

Now showing items 1-2 of 2

    • Chromosomal Instability in Mouse Embryonic Fibroblasts Null for the Transcriptional Co-Repressor Ski 
      Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo; Aguirre, Adam; Ueki, Nobuhide; Toro, Jessica; Colmenares, Clemencia; Hayman, Michael J. (WILEY-BLACKWELL, 2012-01)
      Ski is a transcriptional regulator that has been considered an oncoprotein given its ability to induce oncogenic transformation in avian model systems. However, studies in mouse and in some human tumor cells have also ...
    • The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A 
      Rivas, Solange; Armisen Yáñez, Ricardo; Rojas, Diego A.; Maldonado Maldonado, Edio; Huerta, Hernán; Tapia, Julio C.; Espinoza, Jaime; Colombo, Alicia; Michea Acevedo, Luis; Hayman, Michael J.; Marcelain Cubillos, Katherine (Wiley & Sons, 2016)
      Oncogenic kinase Aurora A (AURKA) has been found to be overexpresed in several tumors including colorectal, breast, and hematological cancers. Overexpression of AURKA induces centrosome amplification and aneuploidy and it ...