Browsing by Author "Inestrosa, Nibaldo C."

Now showing items 1-4 of 4

    • Heparin activates Wnt signaling for neuronal morphogenesis 
      Colombres, Marcela; Henríquez, Juan Pablo; Reig, Germán; Scheu, Jessica; Calderón, Rosario; Alvarez, Alejandra; Brandan, Enrique; Inestrosa, Nibaldo C. (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-09)
      Writ factors are secreted ligands that affect different aspects of the nervous system behavior like neurodevelopment, synaptogenesis and neurodegeneration. In different model systems, Wnt signaling has been demonstrated ...
    • Localization, specific activity, and molecular forms of acetylcholinesterase in developmental stages of the ... 
      Kemmerling Weis, Ulrike; Cabrera, G. F.; Campos, E. O.; Inestrosa, Nibaldo C.; Galanti Garrone, Norbel (WILEY-LISS, 2006-02)
      The nervous system of flatworms is quite simple although there is increasing evidence indicating that it is chemically complex. Studies of the nervous system in these animals have only been performed in the larval stage ...
    • Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its ... 
      Cavieres, Viviana A.; González, Alexis; Muñoz, Vanessa C.; Yefi, Claudia P.; Bustamante, Hianara A.; Barraza, Rafael R.; Tapia Rojas, Cheril; Otth, Carola; Barrera, María José; González, Carlos; Mardones, Gonzalo A.; Inestrosa, Nibaldo C.; Burgos, Patricia V. (Public Library Science, 2015)
      Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-beta (A beta) peptide. We have previously shown that the compound tetrahydrohyperforin (IDN5706) prevents accumulation ...
    • Wnt-5a Modulates Recycling of Functional GABAA Receptors on Hippocampal Neurons 
      Cuitino, Loreto; Godoy, Juan A.; Farías, Ginny G.; Couve Correa, Andrés; Bonansco, Christian; Fuenzalida, Marco; Inestrosa, Nibaldo C. (2010-06-23)
      GABAA receptors (GABAA-Rs) play a significant role in mediating fast synaptic inhibition and it is the main inhibitory receptor in the CNS. The role of Wnt signaling in coordinating synapse structure and function in the ...