Browsing by Author "Jara Sandoval, José"

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    • Comparative effects of superoxide anion and hydrogen peroxide on microsomal and cytosolic glutathione ... 
      Letelier, María Eugenia; Molina Berríos, Alfredo Enrique; Cortés-Troncoso, Juan; Jara Sandoval, José; Müller, Andrea; Aracena Parks, Paula (2010)
      Glutathione S-transferases (GSTs) are isoenzymes occurring in the cytoplasm and as integral membrane proteins. In addition to their role in drug metabolism by conjugating electrophilic and lipophilic compounds with glutathione ...
    • Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism 
      Letelier, María Eugenia; Jara Sandoval, José; Molina Berríos, Alfredo Enrique; Faúndez, Mario; Aracena-Parks, Paula; Aguilera, Felipe (2010)
      Melatonin, an endogenous hormone, is used as an antioxidant drug in doses quite higher than the endogenous circulating levels of this hormone. Hepatic endoplasmic reticulum contains the cytochrome P450 (CYP450) system, ...