Browsing by Author "Klimes, Iwar"

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    • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations 
      Pearson, Ewan R.; Flechtner, Isabelle; Njølstad, Pal R.; Malecki, Maciej T.; Flanagan, Sarah E.; Larkin, Brian; Ashcroft, Frances M.; Klimes, Iwar; Codner Dujovne, Ethel; Lotova, Violeta; Slingerland, Annabelle S.; Shield, Julian; Robert, Jean-Jacques; Holst, Jens J.; Clark, Penny M.; Ellard, Sian; Søvik, Oddmund; Polak, Michel; Hattersley, Andrew T. (MASSACHUSETTS MEDICAL SOC, 2006-08-03)
      BACKGROUND: Heterozygous activating mutations in KCNJ11, encoding the Kir6.2 subunit of the ATP-sensitive potassium (K(sub ATP)) channel, cause 30 to 58 percent of cases of diabetes diagnosed in patients under six months ...