Browsing by Author "Quintanilla González, María Elena"
Now showing items 1-20 of 30
-
Ezquer, Fernando; Quintanilla González, María Elena; Morales Retamales, Eugenia; Santapaul, Daniela; Munita, José Manuel; Moya Flores, Francisco; Ezquer, Marcelo; Herrera Marschitz, Mario; Israel Jacard, Yedy (Elsevier, 2022)Rationale: Gut microbiota communicates information to the brain. Some animals are born with a gut microbiota that predisposes to high alcohol consumption, and transplantation of fecal material from alcoholics to mice ...
-
Berrios Cárcamo, Pablo; Quezada, Mauricio; Santapau, Daniela; Morales Retamales, Eugenia; Olivares, Belén; Ponce, Carolina; Ávila, Alba; Gregorio, Cristian de; Ezquer, Marcelo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy; Ezquer, Fernando (MDPI, 2022)An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in ...
-
Quintanilla González, María Elena; Tampier de Jong, Lutske (1995)The acetaldehyde (AcH) oxidizing capacity of total brain homogenates from the genetically high-ethanol consumer (UChB) appeared to be greater than that of the low-ethanol consumer (UChA) rats. To gain further information ...
-
Tampier de Jong, Lutske; Sánchez, Eliana; Quintanilla González, María Elena (Carfax Publishing Company, 1996)We have observed that blood acetaldehyde (AcH) levels after an ethanol dose were significantly higher in disulfiram-pre-treated UChA (low ethanol consumer) than in UChB (high ethanol consumer) rats. In order to explore ...
-
Ezquer, Fernando; Quintanilla González, María Elena; Morales, Paola; Ezquer, Marcelo; Lespay Rebolledo, Carolyne; Herrera Marschitz, Mario; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2019)© 2017 Society for the Study of Addiction Neuroinflammation has been reported to follow chronic ethanol intake and may perpetuate alcohol consumption. Present studies determined the effect of human mesenchymal stem cells ...
-
Quintanilla González, María Elena; Morales Retamales, Paola; Ezquer, Fernando; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel, Yedy (Frontiers Media, 2021)Background Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the ...
-
Tampier de Jong, Lutske; Quintanilla González, María Elena; Karahanian, Eduardo; Rivera Meza, Mario; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (2013)Background: Animals that have chronically consumed alcohol and are subsequently deprived of it markedly increase their intake above basal levels when access to alcohol is reinstated. Such an effect, termed the alcohol ...
-
Mattalloni, M. S.; Salinas, C.; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy; Cancela, L. M.; Rivera Meza, Mario; Virgolini, M. B. (Oxford Univ Press, 2015)
-
Quintanilla González, María Elena; Callejas, Orlando; Tampier de Jong, Lutske (2002)We have previously found the existence of a relation between activity of the brain mitochondrial aldehyde dehydrogenase (ALDH2) and consumption of ethanol in rats of the low-alcohol-drinking (UChA) and the high-alcohol-drinking ...
-
Quintanilla González, María Elena; Rivera Meza, Mario; Berríos Cárcamo, Pablo; Salinas Luypaert, Catalina; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Wiley-Blackwell, 2016)Background: A number of studies have shown that acetaldehyde synthesized in the brain is necessary to induce ethanol (EtOH) reinforcement in naive animals (acquisition phase). However, after chronic intake is achieved ...
-
Tampier de Jong, Lutske; Quintanilla González, María Elena; Contreras, Selfa; Segovia-requelme, Natividad; Mardones, Jorge (1984)This paper is an inventory of some behavioural, biochemical and pharmacological similarities and differences between two inbred strains of Wistar rats differing in voluntary consumption of ethanol, namely: UChA and UChB ...
-
Tampier de Jong, Lutske; Quintanilla González, María Elena (2002)Acute tolerance that develops within minutes of ethanol exposure appears to influence the apparent acute behavioral sensitivity of laboratory animals to ethanol actions. The existence of a correlation between voluntary ...
-
Tampier de Jong, Lutske; Valenzuela, Mario; González, Sandra; Cayo, Bernardita; Quintanilla González, María Elena (1997)Rats genetically selected for their different ethanol voluntary consumption, UChA (low consumer) and UChB (high consumer) were used. Naive UChA and UChB rats or submitted to ethanol chronic exposure, received an IP dose ...
-
Quintanilla González, María Elena; Sepúlveda, Sandra; Tampier de Jong, Lutske (1993)Acetaldehyde (AcH) levels in blood samples taken from different zones of the vascular system 2 h after a p.o. dose of ethanol (2.76 g/kg) were studied in UChA (low ethanol consumer) and UChB (high ethanol consumer) rats ...
-
Mardones, Jorge; Quintanilla González, María Elena (Elsevier Inc., 1996)The effect of bromocriptine (stimulant of dopaminergic D2 receptors) on the daily consumption of 10% v/v ethanol solution, distilled water, and solid food, under free-choice conditions, was measured in nine genetically low ...
-
Tampier de Jong, Lutske; Quintanilla González, María Elena; Mardones, Jorge (1985)It has previously been reported that the introduction of a new issue (D1) of a stock diet (D0) caused a significant decrease in voluntary ethanol consumption in rats of our UChA (low ethanol consumer) and UChB (high ethanol ...
-
Karahanian, Eduardo; Rivera Meza, Mario; Quintanilla González, María Elena; Israel Jacard, Yedy (Oxford Univ Press, 2015)
-
Israel Jacard, Yedy; Quintanilla González, María Elena; Karahanian, Eduardo; Rivera Meza, Mario; Herrera-Marschitz Muller, Mario (Wiley-Blackwell, 2015)This review analyzes literature that describes the behavioral effects of 2 metabolites of ethanol (EtOH): acetaldehyde and salsolinol (a condensation product of acetaldehyde and dopamine) generated in the brain. These ...
-
Israel Jacard, Yedy; Rivera Meza, Mario; Karahanian, Eduardo; Quintanilla González, María Elena; Tampier de Jong, Lutske; Morales Retamales, Paola; Herrera-Marschitz Muller, Mario (FRONTIERS RESEARCH FOUNDATION, 2013-07-08)Ethanol is metabolized into acetaldehyde mainly by the action of alcohol dehydrogenase in the liver, while mainly by the action of catalase in the brain. Aldehyde dehydrogenase-2 metabolizes acetaldehyde into acetate in ...
-
Ocaranza, Paula; Quintanilla González, María Elena; Tampier de Jong, Lutske; Karahanian, Eduardo; Sapag, Amalia; Israel Jacard, Yedy (2008)Background: Some gene polymorphisms strongly protect against the development of alcoholism. A large proportion of East Asians carry a protective inactivating mutation in aldehyde dehydrogenase (ALDH2*2). These subjects ...