Browsing by Subject "Gallbladder cancer"

Now showing items 1-11 of 11

    • ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans 
      Boekstegers, Félix; Marcelain Cubillos, Katherine; Barahona Ponce, Carol; Báez Benavides, Pablo F.; Müller, Bettina; Toro, Gonzalo de; Retamales, Javier; Barajas Barajas, Olga; Ahumada Olea, Mónica; Morales, Erik; Rojas, Armando; Sanhueza, Verónica; Loader, Denisse; Rivera, María Teresa; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, María Enriqueta; Gabler, Fernando; Spencer, Loreto; Olloquequi, Jordi; González Silos, Rosa; Fischer, Christine; Scherer, Dominique; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes Guajardo, Macarena; González-José, Rolando; Bedoya, Gabriel; Bortolini, María C.; Canizales, Samuel; Gallo, Carla; Ruiz Linares, Andrés; Rothhammer, Francisco; Bermejo, Justo Lorenzo (Elsevier, 2020)
      Background: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
    • Association of chili pepper consumption, low socioeconomic status and longstanding gallstones with gallbladder ... 
      Serra, Iván; Yamamoto, Masaharu; Calvo, Alfonso; Cavada Chacón, Gabriel; Báez, Sergio; Endoh, Kazuo; Watanabe, Hidenobu; Tajima, Kazuo (2002)
      We explored the risk factors for gallbladder cancer and explanations for its sharp and constant incidence increase in Chile since the 1970s. We compared 114 consecutive patients with verified gallbladder cancer, diagnosed ...
    • Gallbladder cancer and nutritional risk factors in Chile 
      Navarro Rosenblatt, Deborah; Duran Agueero, Samuel (Aula Médica, 2016)
      Gallbladder cancer is the most malign neoplasm of the binary tract. Chile presents the third highest prevalence of gallbladder cancer in the Americas, being Chilean women from the city of Valdivia the ones with the highest ...
    • Gallbladder cancer and nutritional risk factors in Chile Cáncer de vesícula biliar en Chile y factores ... 
      Navarro-Rosenblatt, Deborah; Durán Agüero, Samuel (Grupo Aula Medica S.A., 2016)
      © 2016, Grupo Aula Medica S.A. All rights reserved. Gallbladder cancer is the most malign neoplasm of the biliary tract. Chile presents the third highest prevalence of gallbladder cancer in the Americas, being Chilean women ...
    • High CD8(+) and absence of Foxp3(+) T lymphocytes infiltration in gallbladder tumors correlate with prolonged ... 
      Fluxá Rojas, Paula; Rojas Sepúlveda, Daniel; Gleisner, María Alejandra; Tittarelli, Andrés; Villegas, Pablo; Tapia, Loreto; Rivera, María Teresa; López Nitsche, Mercedes; Catán, Felipe; Uribe Maturana, Mario; Salazar Onfray, Flavio (BIOMED Central Ltd., 2018)
      Background: Gallbladder cancer (GBC), although infrequent in industrialized countries, has high incidence rates in certain world regions, being a leading cause of death among elderly Chilean women. Surgery is the only ...
    • Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and ... 
      D’Afonseca, Vívian; Arencibia, Ariel D.; Echeverría Vega, Álex; Cerpa, Leslie; Cayún, Juan P.; Varela Figueroa, Nelson; Salazar, Marcela; Quiñones Sepúlveda, Luis (SAGE, 2020)
      Prognostic markers for cancer can assist in the evaluation of survival probability of patients and help clinicians to assess the available treatment modalities. Gallbladder cancer (GBC) is a rare tumor that causes 165 087 ...
    • RNA Sequencing of hepatobiliary cancer cell lines: Data and applications to mutational and transcriptomic profiling 
      Scherer, Dominique; Dávila López, Marcela; Goeppert, Benjamín; Abrahamsson, Sanna; González Silos, Rosa; Nova, Igor; Marcelain Cubillos, Katherine; Roa, Juan C.; Ibberson, David; Umu, Sinan U.; Ballestad Rounge, Trine; Roessler, Stephanie; Bermejo, Justo Lorenzo (MDPI, 2020)
      Simple Summary Research on gallbladder cancer (GBC) has been largely neglected and molecular GBC data is underrepresented in public databases. Cancer cell lines constitute a valuable tool to examine the mechanisms of ...
    • A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy 
      Jiménez de la Jara, Jorge; Bastías, Gabriel; Ferreccio, Catterina; Moscoso, Cristian; Sagues, Sofía; Cid, Camilo; Bronstein, Eduardo; Herrera, Cristian; Nervi, Bruno; Corvalán, Alejandro; Velásquez, Ethel V.; González, Pamela; Castellón Vera, Enrique; Bustamante, Eva; Oñate, Sergio; McNerney, Eileen; Sullivan, Richard; Owen, Gareth I. (BioMed Central, 2015)
      Introduction: The South American country Chile now boasts a life expectancy of over 80 years. As a consequence, Chile now faces the increasing social and economic burden of cancer and must implement political policy to ...
    • The evaluation of 17 gastrointestinal tumor markers reveals prognosis value for MUC6, CK17, and CD10 in ... 
      Carrasco, Cristian; Tittarelli, Andrés; Paillaleve, Natalia; Pozo, Maeva del; Rojas Sepúlveda, Daniel Alberto; Barría Catricura, Omar André; Fluxá Rojas, Paula Andrea; Hott, Melissa; Martin, Carolina; Quezada Monrás, Claudia Andrea; Salazar Onfray, Flavio Andres (MDPI, 2021)
      Gallbladder cancer (GBC) is an aggressive and highly lethal disease with relatively low global incidence, but one that constitutes a major health problem in Asian and Latin American countries, particularly in Chile. The ...
    • Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer 
      Rojas-Sepúlveda, Daniel; Tittarelli, Andrés; Gleisner, María Alejandra; Ávalos, Ignacio; Pereda, Cristián; Gallegos, Iván; González, Fermín Eduardo; López, Mercedes Natalia; Butte, Jean Michel; Roa, Juan; Fluxá, Paula; Salazar Onfray, Flavio (Springer Science and Business Media Deutschland GmbH, 2018)
      © 2018, The Author(s). Immunotherapy based on checkpoint blockers has proven survival benefits in patients with melanoma and other malignancies. Nevertheless, a significant proportion of treated patients remains refractory, ...
    • Validation of an NGS panel designed for detection of actionable mutations in tumors common in latin america 
      Salvo, Mauricio; González Feliu, Evelin; Toro, Jéssica; Gallegos Méndez, Iván; Maureira Caviedes, Ignacio Andrés; Miranda González, Nicolás; Barajas Barajas, Olga Beatriz; Bustamante, Eva; Ahumada Olea, Mónica Beatriz; Colombo Flores, Alicia Angelina; Armisen, Ricardo; Villaman, Camilo; Ibáñez, Carolina; Bravo, María Loreto; Sanhueza, Verónica; Spencer, M. Loreto; Toro, Gonzalo de; Morales, Erik; Bizama, Carolina; García, Patricia; Carrasco, Ana María; Gutiérrez Cordero, Lorena; Bermejo, Justo; Verdugo Salgado, Ricardo Alejandro; Marcelain Cubillos, Katherine Jenny (MDPI, 2021)
      Next-generation sequencing (NGS) is progressively being used in clinical practice. However, several barriers preclude using this technology for precision oncology in most Latin American countries. To overcome some of these ...