Browsing by Subject "Identification"

Now showing items 1-4 of 4

    • Exome Sequencing in an Admixed Isolated Population Indicates NFXL1 Variants Confer a Risk for Specific ... 
      Villanueva Bianchini, Pía; Nudel, Ron; Hoischen, Alexander; Fernández, María Angélica; Simpson, Nuala H.; Gilissen, Christian; Reader, Rose H.; Jara Sosa, Lilian; Echeverry, María Magdalena; Francks, Clyde; Baird, Gillian; Conti-Ramsden, Gina; O’Hare, Anne; Bolton, Patrick F.; Hennessy, Elizabeth R.; Palomino, Hernán; Carvajal Carmona, Luis; Veltman, Joris A.; Cazier, Jean-Baptiste; Barbieri Ortiz, Zulema de,; Fisher, Simon E.; Newbury, Dianne F. (Public Library Science, 2015)
      Children affected by Specific Language Impairment (SLI) fail to acquire age appropriate language skills despite adequate intelligence and opportunity. SLI is highly heritable, but the understanding of underlying genetic ...
    • Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21 
      Carreras Sureda, Amado; Rubio Moscardo, Fanny; Olvera, Alex; Argilaguet, Jordi; Kiefer, Kerstin; Mothe, Beatriz; Meyerhans, Andreas; Brander, Christian; Vicente, Rubén (Public Library Science, 2016)
      Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression ...
    • STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population 
      Canesin, Giacomo; Maggio, Valentina; Palominos, Macarena; Stiehm, Anna; Contreras, Héctor R; Castellón, Enrique A.; Morote, Juan; Paciucci, Rosanna; Maitland, Norman J.; Bjartell, Anders; Hellsten, Rebecka (Nature Research, 2020)
      Cancer stem cells (CSCs) are a small subpopulation of quiescent cells with the potential to differentiate into tumor cells. CSCs are involved in tumor initiation and progression and contribute to treatment failure through ...
    • The non-receptor tyrosine phosphatase type 14 blocks caveolin-1- enhanced cancer cell metastasis 
      Díaz Valdivia, Natalia; Díaz, Jorge; Contreras, Pamela; Campos, América; Rojas Celis, Victoria; Burgos Ravanal, Renato; Lobos González, Lorena; Torres Gómez, Vicente; Pérez, Viviana I.; Frei, Balz; Leyton Campos, Lisette; Quest, Andrew F. G. (Nature, 2020)
      Caveolin-1 (CAV1) enhanced migration, invasion, and metastasis of cancer cells is inhibited by co-expression of the glycoprotein E-cadherin. Although the two proteins form a multiprotein complex that includes beta-catenin, ...