Now showing items 1-7 of 7

    • Navarro, Montserrat; Carvajal, Francisca; Lerma Cabrera, José Manuel; Cubero, Inmaculada; Picker, Mitchell J.; Thiele, Todd E. (Blackwell, 2015)
      Background—The non-selective opioid receptor antagonist, naltrexone (NAL), reduces alcohol (ethanol) consumption in animals and humans and is an approved medication for treating alcohol abuse disorders. Proopiomelanocortin ...
    • Miranda, Hugo; Sierralta, Fernando; Lux, Sebastian; Troncoso, Rocío; Ciudad, Natalia; Zepeda Iriarte, Ramiro; Zanetta, Pilar; Noriega, Viviana; Prieto, Juan Carlos (Elsevier, 2015)
      Background: Pain is one of the most common problems in clinical medicine. There is considerable evidence that pharmacologic approaches are the most widely used therapeutic options to ameliorate persistent or chronic pain. ...
    • Sir Petermann, Teresa; López, G.; Castillo, T.; Calvillán,; Rabenbauer, B.; Wildt, L. (1998)
      A total of 12 women (24.2 ± 1.6 years old, BMI 36.7 ± 1.5 Kg/m2) with hyperandrogenism (HA) and with normal glucose tolerance test were studied to evaluate the involvement of endogenous opioids in the pathophysiology of ...
    • Wildt, L.; Sir Petermann, Teresa; Leyendecker, G.; Waibel-Treber, S.; Rabenbauer, B. (1993)
      One-hundred-and-thirty-eight women suffering from hypothalamicor hyperandrogenic ovarian failure were treatedwith daily doses of 25-150 mg of the opiate antagonist naltrexone for 4-100 weeks.In patients with hypothalamicovarian ...
    • Miranda, Hugo F.; Noriega, Viviana; Prieto, Juan Carlos (2012)
      In the treatment of acute and chronic pain the most frequently used drugs are nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., paracetamol; opioids, e.g., tramadol, and a group of drugs called coanalgesics or adjuvants ...
    • Berríos Cárcamo, Pablo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Vasiliou, Vasilis; Zapata Torres, Gerald; Rivera Meza, Mario (Frontiers Media S.A., 2017)
      © 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...
    • Quintanilla González, María Elena; Rivera Meza, Mario; Berríos Cárcamo, Pablo; Bustamante, Diego; Buscaglia, Marianne; Morales, Paola; Karahanian, Eduardo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Elsevier Inc., 2014)
      © 2014 Elsevier Inc.Salsolinol is formed non-enzymatically when ethanol-derived acetaldehyde binds to dopamine, yielding 2 distinct products, i.e., salsolinol and isosalsolinol. Early animal studies, revealing that salsolinol ...