Now showing items 1-16 of 16

    • Abbate, F.; Madrigrano, M.; Scopitteri, T.; Levanti, M.; Cobo, J. M.; Germana, Antonino; Vega Velásquez, Juan Andrés; Laurà, Rosaria (Elsevier, 2016)
      The neuromasts are the morphofunctional unit of the lateral line system serving as mechanosensors for water flow and movement. The mechanisms underlying the detection of the mechanical stimuli in the vertebrate mechanosensory ...
    • Levanti, M.; Randazzo, B.; Viña, E.; Montalbano, G.; García Suárez, O.; Germanà, A.; Vega, J. A.; Abbate, F. (Elsevier, 2016)
      Sensory information from the environment is required for life and survival, and it is detected by specialized cells which togethermakeup the sensory system. The fish sensory system includes specialized organs that are ...
    • Pulgar, Eduardo; Schwayer, Cornelia; Guerrero, Néstor; López, Loreto; Márquez, Susana; Hartel, Steffen; Soto, Rodrigo; Heisenberg, Carl-Philipp; Concha Nordemann, Miguel Luis Angel (Elife Sciences Publications, 2021)
      The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here, we uncovered a mechanism of progenitor ...
    • Rojas, Diego A.; Pérez Munizaga, Daniela A.; Centanin, Lazaro; Antonelli, Marcelo; Wappner, Pablo; Allende Connelly, Miguel; Reyes, Ariel E. (2007)
      Hypoxia-inducible factors (HIFs) regulate gene expression in response to hypoxia and in vertebrates they are known to participate in several developmental processes, including angiogenesis, vasculogenesis, heart and central ...
    • Kudoh, Tetsuhiro; Concha, Miguel L.; Houart, Corinne; Dawid, Igor B.; Wilson, Stephen W. (2004)
      Studies in fish and amphibia have shown that graded Bmp signalling activity regulates dorsal-to-ventral (DV) patterning of the gastrula embryo. In the ectoderm, it is thought that high levels of Bmp activity promote epidermal ...
    • Paredes Zúñiga, Susana; Morales, Rodrigo A.; Muñoz Sánchez, Salomé; Muñoz Montecinos, Carlos Humberto.; Parada, Margarita; Tapia, Karina; Rubilar, Carlos; Allende Connelly, Miguel; Peña, Oscar A. (Springer Verlag, 2017)
      © 2017, Springer-Verlag Berlin Heidelberg. Neutrophils are a major component of the innate immune response and the most abundant circulating cell type in humans and zebrafish. The CXCL12/CXCR4 ligand receptor pair plays a ...
    • Signore Ahumada, Iskra; Jerez, Carolina; Figueroa, Diego; Suazo Sanhueza, José Lorenzo; Marcelain Cubillos, Katherine; Cerda Arancibia, Óscar; Colombo Flores, Alicia (Wiley, 2016)
      Background: Orofacial clefts (OFCs) are common birth defects, which include a range of disorders with a complex etiology affecting formation of craniofacial structures. Some forms of syndromic OFCs are produced by defects ...
    • Varas, Macarena; Fariña, Alonso; Díaz Pascual, Francisco; Ortíz-Severín, Javiera; Marcoleta, Andrés E.; Allende Connelly, Miguel; Santiviago, Carlos A.; Chávez, Francisco P. (Elsevier B.V., 2017)
      © 2017The zebrafish model has been used to determine the role of vertebrate innate immunity during bacterial infections. Here, we compare the in vivo immune response induced by GFP-tagged Salmonella Typhimurium inoculated ...
    • Tada, Masazumi; Concha, Miguel L.; Heisenberg, Carl Philipp (Elsevier Ltd, 2002)
      Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt ...
    • Oteiza, Pablo; Köppen, Mathias; Krieg, Michael; Pulgar, Eduardo; Farias, Cecilia; Melo, Cristina; Preibisch, Stephan; Müller, Daniel; Tada, Masazumi; Hartel, Steffen; Heisenberg, Carl-Philipp; Concha, Miguel L. (Company of Biologists Ltd, 2010)
      Organ formation requires the precise assembly of progenitor cells into a functional multicellular structure. Mechanical forces probably participate in this process but how they influence organ morphogenesis is still unclear. ...
    • Caruffo, Mario; Navarrete, Natalie C.; Salgado, Oscar A.; Faúndez, Nelly B.; Gajardo, Miguel C.; Feijóo, Carmen G.; Reyes-Jara, Angélica; García, Katherine; Navarrete, Paola (Frontiers Media S.A., 2016)
      © 2016 Caruffo, Navarrete, Salgado, Faúndez, Gajardo, Feijóo, Reyes-Jara, García and Navarrete. We investigated mechanisms involved in the protection of zebrafish (Danio rerio) larvae by two probiotic candidate yeasts, ...
    • Albornoz, Amelina; Yáñez López, José; Foerster, Claudia; Aguirre, Celeste; Pereiro, Luisa; Burzio, Verónica; Moraga, Mauricio; Reyes, Ariel E.; Antonelli, Marcelo (Society of Biology of Chile, 2007)
      Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described ...
    • Concha, Miguel L. (2004)
      Lateralisation is an attractive and intriguing feature of the vertebrate CNS studied for decades in the different disciplines of the neurosciences. Due to the complexity of the phenomena and intrinsic limitations of the ...
    • Figueroa, Diego; Signore Ahumada, Iskra; Araneda, Óscar; Contreras Muñoz, Héctor; Concha Nordemann, Miguel; García Carrasco, Carlos (Taylor and Francis, 2020)
      Okadaic acid-group (OA-group) is a set of lipophilic toxins produced only in seawater by species of theDinophysisandProrocentrumgenera, and characterized globally by being associated with harmful algal blooms (HABs). The ...
    • Cáceres Lluch, Mónica; Ortiz, Liliana; Recabarren, Tatiana; Romero, Aníbal; Colombo Flores, Alicia; Leiva Salcedo, Elías; Varela Lekanda, Diego; Rivas, José; Silva, Ian; Morales, Diego; Campusano, Camilo; Almarza, Óscar; Simon, Felipe; Toledo Araya, Héctor; Park, Kang-Sik; Trimmer, James S.; Cerda, Óscar (Public Library Science, 2015)
      Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations. TRPM4 is a ...
    • Ulloa, Pilar E.; Iturra, Patricia; Neira Roa, Roberto; Araneda, Cristian (2011)
      Zebrafish (Danio rerio) is a common research model in fish studies of toxicology, developmental biology, neurobiology and molecular genetics; it has been proposed as a possible model organism for nutrition and growth studies ...