Facultad de Medicina: Recent submissions

Now showing items 581-600 of 12973

    • Estudio predictivo de sobrevida en base a una propuesta de genes en pacientes con Glioblastoma 
      Valdebenito Silva, Jessica (Universidad de Chile, 2019)
      La presente tesis pretende estudiar un conjunto de genes de interés debido a la particular coincidencia de dichos genes en estudios experimentales previos realizados en células madre de glioblastoma en ratones, células ...
    • Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases 
      Legaz, Agustina; Abrevaya, Sofia; Dottori, Martin; González Campo, Cecilia; Birba, Agustina; Martorell Caro, Miguel; Aguirre, Julieta; Slachevsky Chonchol, Andrea María; Aranguiz, Rafael; Serrano, Cecilia; Gillan, Claire M.; Leroi, Iracema; Garcıa, Adolfo M.; Fittipaldi, Sol; Ibañez, Agustín (Oxford University Press, 2022)
      Social feedback can selectively enhance learning in diverse domains. Relevant neurocognitive mechanisms have been studied mainly in healthy persons, yielding correlational findings. Neurodegenerative lesion models, coupled ...
    • Urinary Extracellular Vesicles as a source of NGAL for diabetic kidney disease evaluation in children and ... 
      Ugarte, Francisca; Santapau, Daniela; Gallardo, Vivian; Garfias, Carolina; Yizmeyián, Anahí; Villanueva, Soledad; Sepúlveda, Carolina; Rocco, Jocelyn; Pasten, Consuelo; Urquid, Cinthya; Cavada Chacón, Gabriel Alfredo; San Martín, Pamela; Cano Schuffeneger, Francisco Javier; Irarrázaval, Carlos E. (Frontiers Media, 2022)
      Background: Tubular damage has a role in Diabetic Kidney Disease (DKD). We evaluated the early tubulointerstitial damage biomarkers in type-1 Diabetes Mellitus (T1DM) pediatric participants and studied the correlation with ...
    • Evidence mapping of the treatments for breast cancer–related lymphedema 
      Al-Sakka, Ali M.; Masia, Jaume; Auladell-Rispau, Ariadna; Shamardal, Aliaa I.; Vasconcello Castillo, Luis Eduardo; Sola, Ivan; Bonfill, Xavier (Lippincott Williams & Wilkins, 2022)
      Background: Women treated for breast cancer are facing a lifetime risk of developing lymphedema, which occurs in up to 40% of this population. There is a lack of evidence and limited knowledge regarding the treatment of ...
    • Do children with developmental language disorder activate scene knowledge to guide visual attention? effect ... 
      Helo Herrera, Andrea Verónica; Guerra Gil, Ernesto Eduardo; Coloma Tirapegui, Carmen Julia; Aravena Bravo, Paulina Alexandra; Rämä, Pia (Frontiers Media, 2022)
      Our visual environment is highly predictable in terms of where and in which locations objects can be found. Based on visual experience, children extract rules about visual scene configurations, allowing them to generate ...
    • A Real-time PCR assay for detection of low pneumocystis jirovecii levels 
      Ruiz Ruiz, Susana; Ponce Olmos, Carolina Angélica; Pesantes, Nicole; Bustamante, Rebeca; Gatti Orellana, Gianna; San Martin, Viviana; Gutiérrez, Mireya; Bórquez, Pamela; Vargas Munita, Sergio Luis; Magne, Fabien; Calderón, Enrique J.; Pérez Brocal, Vicente; Moya, Andrés (Frontiers Media, 2022)
      Here we report a new real-time PCR assay using SYBR Green which provides higher sensitivity for the specific detection of low levels of Pneumocystis jirovecii. To do so, two primer sets were designed, targeting the family ...
    • Apathy, executive function, and emotion recognition are the main drivers of functional impairment in ... 
      Musa Salech, Gada; Lillo Zurita, Patricia del Carmen; Van der Hiele, Karin; Méndez Orellana, Carolina; Ibáñez, Agustín; Slachevsky Chonchol, Andrea María (Frontiers Media, 2022)
      Background: The cognitive and neuropsychiatric deficits present in patients with behavioral variant frontotemporal dementia (bvFTD) are associated with loss of functionality in the activities of daily living (ADLs). The ...
    • Abrocitinib induction, randomized withdrawal, and retreatment in patients with moderate-to-severe atopic ... 
      Blauvelt, Andrew; Silverberg, Jonathan I.; Lynde, Charles W.; Bieber, Thomas; Eisman, Samantha; Zdybski, Jacek; Gubelin, Walter; Simpson, Eric L.; Valenzuela Ahumada, Fernando Alfredo; Criado, Paulo Ricardo; Lebwohl, Mark G.; Feeney, Claire; Khan, Tahira; Biswas, Pinaki; DiBonaventura, Marco; Valdez, Hernán; Cameron, Michael C.; Rojo, Ricardo (Elsevier, 2022)
      Background: The heterogeneous course of moderate-to-severe atopic dermatitis necessitates treatment flexibility. Objective: We evaluated the maintenance of abrocitinib-induced response with continuous abrocitinib ...
    • The Association between fasting glucose and sugar sweetened beverages intake is greater in latin americans ... 
      López-Portillo García, María de Lourdes; Huidobro, Andrea; Tobar Calfucoy, Eduardo Andrés; Yañez, Cristián; Retamales Ortega, Rocío Mariana; Garrido Tapia, Macarena; Acevedo, Johanna; Paredes, Fabio; Cid Ossandón, Vicente; Ferreccio, Catterina; Verdugo Salgado, Ricardo Alejandro (MDPI, 2022)
      Chile is one of the largest consumers of sugar-sweetened beverages (SSB) world-wide. However, it is unknown whether the effects from this highly industrialized food will mimic those reported in industrialized countries or ...
    • Systematic review: microRNAs as potential biomarkers in mild cognitive impairment diagnosis 
      Ogonowski, Natalia; Salcidua, Stefanny; León Albarracín, Tomás; Chamorro Veloso, Nayaret; Valls, Cristian; Avalos, Constanza; Bisquertt, Alejandro; Rentería, Miguel E.; Orellana, Paulina; Duran Aniotz, Claudia (Frontiers Media, 2022)
      The rate of progression from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD) is estimated at > 10% per year, reaching up to 80-90% after 6 years. MCI is considered an indicator of early-stage AD. In this context, ...
    • Quality of automatic geocoding tools: a study using addresses from hospital record files in Temuco, Chile 
      Quinteros, María Elisa; Blazquez, Carola; Rosas, Felipe; Ayala Pizarro, Salvador Andrés; Ossa García, Ximena Marcela; Delgado Saborit, Juana María; Harrison, Roy M.; Ruiz Rudolph, Pablo Alejandro; Yohannessen Vásquez, Karla Alejandra (Cadernos Saude Publica, 2022)
      Automatic geocoding methods have become popular in recent years, facilitating the study of the association between health outcomes and the place of living. however, rather few studies have evaluated geocoding quality, with ...
    • The Action of 2-aminoethyldiphenyl borinate on the pulmonary arterial hypertension and remodeling of ... 
      Castillo Galán, Sebastián; Parrau Vargas, Daniela Beatriz Angela; Hernández Álvarez, Ismael Charles; Quezada, Sebastián; Díaz Navarrete, Marcela; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Moraga, Fernando A.; Iturriaga, Rodrigo; Llanos Mansilla, Jorge Aníbal; Reyes Catalán, Víctor Roberto (Frontiers Media, 2022)
      Calcium signaling is key for the contraction, differentiation, and proliferation of pulmonary arterial smooth muscle cells. Furthermore, calcium influx through store-operated channels (SOCs) is particularly important in ...
    • The efects of national mental health plans on mental health services development in Chile: retrospective ... 
      Mundt, Adrian Philipp; Martínez Díaz, Pablo Alberto; Jaque Ortiz, Sebastián; Irarrázaval Domínguez, Matías (BMC, 2022)
      Aims To describe changes in mental health services in Chile between 1990 and 2017, and to retrospectively assess the effects of national mental health plans (NMHPs) on mental health services development during this period. ...
    • Redefiniendo el estándar de oro para el reemplazo valvular aórtico: mínimamente invasivo y recuperación acelerada 
      Turner, Eduardo; Iturra, Sebastián; Paulsen, César; Olivares, Gabriel; Portilla, Mario; Canals Cifuentes, María Andrea (Sociedad Médica de Santiago, Chile, 2021)
      Background: Despite being introduced 20 years ago minimally invasive aortic valve replacement is only performed routinely in a minority of patients worldwide. Aim: To report the operative outcome of minimally invasive ...
    • Terapia biológica en pacientes embarazadas con enfermedad inflamatoria intestinal: una visión ampliada sobre su uso 
      Quera, Rodrigo; Núñez F., Paulina; Flores, Lilian (Sociedad Médica de Santiago, Chile, 2021)
    • Violencia contra la mujer durante la gestación y postparto infligida por su pareja en Centros de Atención ... 
      Bella, Maribel; Binfa Esbir, Lorena; Carrasco Parra, Alicia; Cornejo Aravena, Claudia Alejandra; Cavada Chacón, Gabriel Alfredo; Pantoja Manzanarez, Loreto Beatriz (Sociedad Médica de Santiago, Chile, 2021)
      Background: Violence against women (VAW) is a violation of women´s fundamental rights and special attention must be paid during the gestational and postpartum period. Aim: To determine the prevalence of violence ...
    • Homenaje póstumo al Doctor Alejandro Goic (1929-2021), Editor Emérito 
      Reyes Budelovsky, Humberto (Sociedad Médica de Santiago, Chile, 2021)
      Alejandro Goic, M.D., son of Croatian immigrants, graduated as M.D. in 1955, studying at the Catholic University of Chile Medical School. After a residency in internal medicine, he followed post graduate studies in ...
    • Socioeconomic, clinical, and molecular features of breast cancer influence overall survival of Latin American women 
      Almeida, Liz María de; Cortés, Sandra; Vilensky, Marta; Valenzuela, Olivia; Cortés Sanabria, Laura; Souza, Mirian de; Barbeito, Rafael Alonso; Abdelhay, Eliana; Artagaveytia, Nora; Daneri Navarro, Adrian; Llera, Andrea S.; Müller, Bettina; Podhajcer, Osvaldo L.; Velázquez, Carlos; Alcoba, Elsa; Alonso, Isabel; Bravo, Alicia I.; Camejo, Natalia; Carraro, Dirce Maria; Castro, Mónica; Cataldi, Sandra; Cayota, Alfonso; Cerda Villablanca, Mauricio David; Colombo Flores, Alicia Angelina; Crocamo, Susanne; Toro Arreola, Alicia del; Delgadillo Cristerna, Raúl; Delgado, Lucia; Breitenbach, Marisa Dreyer; Fernández, Elmer; Fernández, Jorge; Fernández, Wanda; Franco Topete, Ramón A; Gaete, Fancy; Gómez, Jorge; González Ramírez, Leivy P.; Guerrero, Marisol; Gutiérrez Rubio, Susan A.; Jalfin, Beatriz; López Vázquez, Alejandra; Loria, Dora; Míguez, Silvia; Morán Mendoza, Andres de J.; Morgan Villela, Gilberto; Mussetti, Carina; Nagai, Maria Aparecida; Oceguera Villanueva, Antonio; Reis, Rui M.; Retamales, Javier; Rodríguez, Robinson; Rosales, Cristina; Salas González, Efraín; Segovia, Laura; Sendoya, Juan M.; Silva García, Aída A.; Viña, Stella; Zagame, Livia; Jones, Beth; Szklo, Moysés (Frontiers Media, 2022)
      Molecular profile of breast cancer in Latin-American women was studied in five countries: Argentina, Brazil, Chile, Mexico, and Uruguay. Data about socioeconomic characteristics, risk factors, prognostic factors, and ...
    • Bacterial gut microbiota and infections during early childhood 
      George Carreño, Sergio Andrés; Aguilera, Ximena; Gallardo Schall, Pablo Alfredo; Farfán Urzúa, Mauricio Javier; Lucero Álvarez, Yalda Cecilia; Torres, Juan Pablo; Vidal Álvarez, Roberto Mauricio; O'Ryan Gallardo, Miguel Luis (Frontiers Media, 2022)
      Gut microbiota composition during the first years of life is variable, dynamic and influenced by both prenatal and postnatal factors, such as maternal antibiotics administered during labor, delivery mode, maternal diet, ...
    • Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review 
      Jha, Niraj Kumar; Chen, Wei-Chih; Kumar, Sanjay; Dubey, Rajni; Tsai, Lung-Wen; Kar, Rohan; Jha, Saurabh Kumar; Gupta, Piyush Kumar; Sharma, Ankur; Gundamaraju, Rohit; Pant, Kumud; Mani, Shalini; Singh, Sandeep Kumar; Maccioni Baraona, Ricardo Benjamín; Datta, Tirtharaj; Singh, Sachin Kumar; Gupta, Gaurav; Prasher, Parteek; Dua, Kamal; Dey, Abhijit; Sharma, Charu; Mughal, Yasir Hayat; Ruokolainen, Janne; Kesari, Kavindra Kumar; Ojha, Shreesh (The Royal Society Publishing, 2022)
      Developmental signalling pathways such as Wnt/beta-catenin, Notch and Sonic hedgehog play a central role in nearly all the stages of neuronal development. The term 'embryonic' might appear to be a misnomer to several people ...