Now showing items 641-660 of 12973

    • Núñez Cortés, Rodrigo; Malhue Vidal, Constanza; Gath, Florencia; Valdivia Lobos, Gonzalo; Torres Castro, Rodrigo; Cruz Montecinos, Carlos Eduardo; Martínez Arnau, Francisco M.; Pérez Alenda, Sofía; López Bueno, Rubén; Calatayud, Joaquín (MDPI, 2022)
      Objective: To determine the association between the Charlson comorbidity index (CCI) score after discharge with 6-min walk test (6MWT) 1 year after discharge in a cohort of COVID-19 survivors. Methods: In this prospective ...
    • Espinoza, Sandra; Grunenwald, Felipe; Gomez, Wileidy; García, Felipe; Abarzúa Catalán, Lorena; Oyarce Pezoa, Sebastián; Hernández, María Fernanda; Cortés, Bastián I.; Uhrig, Markus; Ponce de la Vega, Daniela Paz; Durán Aniotz, Claudia; Hetz Flores, Claudio Andres; San Martín Rovirosa, Carol Dazil; Cornejo Corona, Víctor Hugo; Ezquer, Fernando; Parra Ortiz, Valentina María; Behrens Pellegrino, María Isabel Ofelia; Manque, Patricio A.; Rojas Rivera, Diego; Vidal, René L.; Woehlbier, Ute; Nassif, Melissa (MDPI, 2022)
      Alzheimer's disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon ...
    • Landskron Ramos, Glauben Tamara; Dubois Camacho, Karen; Orellana Serradell, Octavio Andrés; Fuente López, Majorie de la; Parada Venegas, Daniela Estefani; Bitrán Ambler, Mirit Luisa; Díaz Jiménez, David; Tang, Shuang; Cidlowski, John A.; Li, Xiaoling; Molina, Héctor; González, Carlos M.; Simian, Daniela; Lubascher, Jaime; Pola, Víctor; Montecino, Martín; Blokzijl, Tjasso; Faber, Klaas Nico; González Burgos, María Julieta; Quera, Rodrigo; Hermoso, Marcela Alejandra (MDPI, 2022)
      Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to ...
    • Castro Abarca, Patricia Bernardita; Bancroft, Matthew J.; Arshad, Qadeer; Kaski, Diego (MDPI, 2022)
      Persistent postural-perceptual dizziness (PPPD) is a common cause of chronic dizziness associated with significant morbidity, and perhaps constitutes the commonest cause of chronic dizziness across outpatient neurology ...
    • Torres Castro, Rodrigo; Solis Navarro, Lilian; Puppo Gallardo, Homero Luis; Alcaraz Serrano, Victoria; Vasconcello Castillo, Luis Eduardo; Vilaró, Jordi; Vera Uribe, Roberto Eugenio (MDPI, 2022)
      Background: Effective treatments for obstructive sleep apnoea (OSA) include positive pressure, weight loss, oral appliances, surgery, and exercise. Although the involvement of the respiratory muscles in OSA is evident, the ...
    • Blumel Mendez, Juan Enrique; Arteaga, Eugenio; Vallejos, Maria Soledad; Chea Vine, Rosa Isabel (Springer, 2019)
      The world population is aging, so it is not uncommon that diseases associated with old age are steadily increasing. Osteoporosis and sarcopenia are two disorders that seriously impair the quality of life in the elderly. ...
    • Castillo Laborde, Carla Cecilia (Universidad de Chile, 2022)
      Objetivo: evaluar el impacto de las GES sobre el acceso, por parte de los beneficiarios del FONASA y las ISAPRE, a medicamentos asociados al tratamiento de la hipertensión y la diabetes en Chile, y del FOFAR, por parte ...
    • Osorio, Julio C.; Blanco Santana, Rancés; Corvalán, Alejandro H.; Muñoz, Juan P.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2022)
      Lung cancer (LC) is the leading cause of cancer death worldwide. Tobacco smoke is the most frequent risk factor etiologically associated with LC, although exposures to other environmental factors such as arsenic, radon or ...
    • Rojas Pirela, Maura Lina; Andrade Alviárez, Diego; Medina, Lisvaneth; Castillo Rivas, Christian Raúl; Liempi Manquel, Ana Isabel; Guerrero Muñoz, Jesús Alejandro Ignacio; Ortega Asencios, Yessica Lisette; Maya Arango, Juan Diego; Rojas, Verónica; Quiñones, Wilfredo; Michels, Paul A.; Kemmerling Weis, Ulrike (Royal Society, 2022)
      MicroRNAs (miRNAs) are a group of small non-coding RNAs present in a wide diversity of organisms. MiRNAs regulate gene expression at a post-transcriptional level through their interaction with the 3 ' untranslated regions ...
    • Méndez Rebolledo, Guillermo; Ager, Amanda L.; Ledezma, Diana; Montanez, Julieta; Guerrero Henríquez, Juan; Cruz Montecinos, Carlos Vicente (PeerJ, 2022)
      Background: It has been well established that proprioception plays a decisive role in shoulder stability and sport performance. Notwithstanding, there is a lack of clear association between active joint position sense ...
    • Castro Masso, Isabel Verónica; Carvajal Garcés, Patricia Alejandra; Jara, Daniela; Aguilera, Sergio; Heathcote Pérez, Benjamín Norman; Barrera, María José; Aliaga Tobar, Víctor Manuel; Maracaja Coutinho, Vinicius; Urzúa Tobar, Ulises; Quest, Andrew Frederick Geoffery; González, Sergio; Claudio, Molina; Hermoso, Marcela Alejandra; González Burgos, María Julieta (Frontiers Media, 2022)
      MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis ...
    • Beñaldo Fuentes, Felipe Augusto; Araya Quijada, Claudio Enrique; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Reyes, Roberto V.; Moraga, Fernando A.; Riquelme Herrera, Alexander Nathan; González Candia, Alejandro; Castillo Galán, Sebastián; Valenzuela, Guillermo J.; Serón Ferré, María Josefa; Llanos, Aníbal J. (Frontiers Media, 2022)
      Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation ...
    • Gajardo Jáuregui, Jean Andre; Espinosa, Francisca; Goycolea, Rodrigo; Oyarzún, Mónica; Muñoz, Irene; Valdebenito, Ana; Pezoa, Carolina (Cuba Editorial, 2022)
      People with mental illness experience stigmatizing attitudes from the general population, including health professionals and students. International studies have estimated the stigma in occupational therapy students towards ...
    • Ping, Hu; Leyton Campos, Lisette; Hagood, James S.; Barker, Thomas H. (Frontiers Media, 2022)
      Thy-1 is a cell surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein that bears a broad mosaic of biological roles across various cell types. Thy-1 displays strong physiological and pathological implications ...
    • Carvajal Gutiérrez, Bielka Victoria; White, Helen; Brooks, Jane; Thomson, Ann M.; Cooke, Alison (Elsevier, 2022)
      Introduction: Policy implementation can be affected by what individuals believe to be right and wrong. When implementing abortion policies, providers' moral beliefs can be relevant in the success of the implementation ...
    • Meissner Haecker, Arturo; Contreras Fernández, Julio José; Valenzuela, Alfonso; Delgado, Byron; Taglioni, Angelinni; De Marinis, Rodrigo; Calvo, Claudio; Soza, Francisco; Liendo, Rodrigo (BMC, 2022)
      Background: Atraumatic full thickness rotator cuff tears (AFTRCT) are common lesions whose incidence increases with age. Physical therapy is an effective conservative treatment in these patients with a reported success ...
    • González Candia, Alejandro; Candia Henríquez, Alejandro Andrés; Paz, Adolfo; Mobarec Lubies, Fuad Cristóbal Rachid; Urbina Varela, Rodrigo; Campo, Andrea del; Herrera Videla, Emilio Augusto; Castillo Peñaloza, Rodrigo Luis (MDPI, 2022)
      More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude ...
    • Díaz Valdivia, Natalia; Simón, Layla; Díaz, Jorge; Martínez Meza, Samuel; López Contreras, Pamela; Burgos Ravanal, Renato; Pérez, Viviana; Frei, Balz; Leyton Campos, Lisette; Quest, Andrew Frederick Geoffery (MDPI, 2022)
      Simple Summary Caveolin-1 (CAV1) is a membrane protein that has been attributed a dual role in cancer, acting at early stages as a tumor suppressor and in later stages of the disease as a promoter of metastasis. In the ...
    • Alfaro Morgado, Tania; Martínez Folgar, Kevin; Vives, Alejandra; Bilal, Usama (Springer, 2022)
      We estimated excess mortality in Chilean cities during the COVID-19 pandemic and its association with city-level factors. We used mortality, and social and built environment data from the SALURBAL study for 21 Chilean ...
    • Godoy, Karina; Sandoval, Cristian; Manterola Barroso, Carlos; Vásquez, Claudio; Sepúlveda, Noelia; Rojas Rauco, Mariana Antonia; Salazar, Luis A. (MDPI, 2022)
      Simple Summary Bone deformities in the axial skeleton represent a frequent bone pathology in farmed salmonids, affecting the quality of life and even increasing mortality. Bone deformation can affect the formation, repair, ...