Haptic-Based Neurorehabilitation in Poststroke Patients: A Feasibility Prospective Multicentre Trial for Robotics Hand Rehabilitation
Author
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Turolla, Andrea
Author
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Daud Albasini, Omar
es_CL
Author
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Oboe, Roberto
es_CL
Author
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Agostini, Michela
es_CL
Author
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Tonin, Paolo
es_CL
Author
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Paolucci, Stefano
es_CL
Author
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Giorgio, Sandrini
es_CL
Author
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Venneri, Annalena
es_CL
Author
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Piron, Lamberto
es_CL
Admission date
dc.date.accessioned
2014-01-29T19:55:04Z
Available date
dc.date.available
2014-01-29T19:55:04Z
Publication date
dc.date.issued
2013
Cita de ítem
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COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE Article Number: UNSP 895492
en_US
Identifier
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DOI: 10.1155/2013/895492
Identifier
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https://repositorio.uchile.cl/handle/2250/126332
General note
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Artículo de publicación ISI.
en_US
Abstract
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Background. Haptic robots allow the exploitation of known motor learning mechanisms, representing a valuable option for motor
treatment after stroke. The aim of this feasibility multicentre study was to test the clinical efficacy of a haptic prototype, for the
recovery of hand function after stroke. Methods. A prospective pilot clinical trial was planned on 15 consecutive patients enrolled
in 3 rehabilitation centre in Italy. All the framework features of the haptic robot (e.g., control loop, external communication, and
graphic rendering for virtual reality) were implemented into a real-time MATLAB/Simulink environment, controlling a five-bar
linkage able to provide forces up to 20 [N] at the end effector, used for finger and hand rehabilitation therapies. Clinical (i.e., Fugl-
Meyer upper extremity scale; nine hold pegboard test) and kinematics (i.e., time; velocity; jerk metric; normalized jerk of standard
movements) outcomes were assessed before and after treatment to detect changes in patients’ motor performance. Reorganization
of cortical activation was detected in one patient by fMRI. Results and Conclusions. All patients showed significant improvements in
both clinical and kinematic outcomes. Additionally, fMRI results suggest that the proposed approachmay promote a better cortical
activation in the brain.