Effects of hypertension and pressure gradient in a human cerebral aneurysm using fluid structure interaction simulations
Author
dc.contributor.author
Valencia Musalem, Álvaro
Author
dc.contributor.author
Torres, Francisco
Admission date
dc.date.accessioned
2019-05-29T13:10:31Z
Available date
dc.date.available
2019-05-29T13:10:31Z
Publication date
dc.date.issued
2017
Cita de ítem
dc.identifier.citation
Journal of Mechanics in Medicine and Biology
Vol. 17, No. 1 (2017) 1750018 (17 pages)
Identifier
dc.identifier.issn
02195194
Identifier
dc.identifier.other
10.1142/S021951941750018X
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/168827
Abstract
dc.description.abstract
Fluid-structure interaction (FSI) simulations were carried out in a human cerebral aneurysm model with the objective of quantifying the effects of hypertension and pressure gradient on the behavior of fluid and solid mechanics. Six FSI simulations were conducted using a hyperelastic Mooney-Rivlin model. Important differences in wall shear stress (WSS), wall displacements, and effective von Mises stress are reported. The hypertension increases wall stress and displacements in the aneurysm region; however, the effects of hypertension on the hemodynamics in the aneurysm region were small. The pressure gradient affects the WSS in the aneurysm and also the displacement and wall stress on the aneurysm. Maximum wall stress with hypertension in the range of rupture strength was found.