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Authordc.contributor.authorArias Bautista, José 
Authordc.contributor.authorSilva, Karla 
Authordc.contributor.authorNeira Carrillo, Andrónico 
Authordc.contributor.authorOrtiz, Liliana 
Authordc.contributor.authorArias Fernández, José 
Authordc.contributor.authorButto, Nicole 
Authordc.contributor.authorFernández Garay, María Soledad 
Cita de ítemdc.identifier.citationCrystals 2020, 10, 797es_ES
Abstractdc.description.abstractBiomineralization is a process in which specialized cells secrete and deliver inorganic ions into confined spaces limited by organic matrices or scaffolds. Chicken eggshell is the fastest biomineralization system on earth, and therefore, it is a good experimental model for the study of biomineralization. Eggshell mineralization starts on specialized dispersed sites of the soft fibrillar eggshell membranes referred to as negatively charged keratan sulfate mammillae. However, the rest of the fibrillar eggshell membranes never mineralizes, although 21% of their amino acids are acidic. We hypothesized that, relative to the mammillae, the negatively charged amino acids of the fibrillar eggshell membranes are not competitive enough to promote calcite nucleation and growth. To test this hypothesis, we experimentally increased the number of negatively charged carboxylate groups on the eggshell membrane fibers and compared it with in vitro calcite deposition of isolated intact eggshell membranes. We conclude that the addition of poly-carboxylated groups onto eggshell membranes increases the number of surface nucleation sites but not the crystal size.es_ES
Patrocinadordc.description.sponsorshipChilean Government National Agency of Research and Development (ANID), grant Fondecyt 1180734es_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.uri*
Keywordsdc.subjectEggshell mineralizationes_ES
Keywordsdc.subjectPoly-glutamic acides_ES
Títulodc.titlePolycarboxylated eggshell membrane scaffold as template for calcium carbonate mineralizationes_ES
Document typedc.typeArtículo de revistaes_ES
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Indexationuchile.indexArtículo de publicación ISI
Indexationuchile.indexArtículo de publicación SCOPUS

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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile