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Authordc.contributor.authorRial Crestelo, Marta 
Authordc.contributor.authorGarcía Otero, Laura 
Authordc.contributor.authorCancemi, Annalisa 
Authordc.contributor.authorGiannone, Mariella 
Authordc.contributor.authorEscazzocchio, Elena 
Authordc.contributor.authorBiterna, Alex 
Authordc.contributor.authorFerriols, Elena 
Authordc.contributor.authorHernández, José Luis 
Authordc.contributor.authorLubusky, Marek 
Authordc.contributor.authorKolarova, Veronika 
Authordc.contributor.authorKrofta, Ladislav 
Authordc.contributor.authorVojtech, Jiri 
Authordc.contributor.authorZohav, Eyal 
Authordc.contributor.authorKrajden, Karina 
Authordc.contributor.authorCruz Martínez, Rogelio 
Authordc.contributor.authorCruz Lemini, Mónica 
Authordc.contributor.authorParra Cordero, Mauro 
Authordc.contributor.authorSocias, Pamela 
Authordc.contributor.authorCrispi, Fatima 
Authordc.contributor.authorLópez, Marta 
Authordc.contributor.authorGratacos, Eduard 
Authordc.contributor.authorFigueras, Francesc 
Admission datedc.date.accessioned2021-04-16T22:58:07Z
Available datedc.date.available2021-04-16T22:58:07Z
Publication datedc.date.issued2020
Cita de ítemdc.identifier.citationFetal Diagnosis and Therapy Volumen: 47 Número: 10 Páginas: 757-764 Oct 2020es_ES
Identifierdc.identifier.other10.1159/000508366
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/179160
Abstractdc.description.abstractObjective:To construct valid reference standards reflecting optimal cerebroplacental ratio and to explore its physiological determinants.Methods:A cohort of 391 low-risk pregnancies of singleton pregnancies of nonmalformed fetuses without maternal medical conditions and with normal perinatal outcomes was created. Doppler measurements of the middle cerebral artery and umbilical artery were performed at 24-42 weeks. Reference standards were produced, and the influence of physiological determinants was explored by nonparametric quantile regression. The derived standards were validated in a cohort of 200 low-risk pregnancies.Results:Maternal body mass index was significantly associated with the 5th centile of the cerebroplacental ratio. For each additional unit of body mass index, the 5th centile was on average 0.014 lower. The derived 5th, 10th, and 50th centiles selected in the validation cohort were 5, 9.5, and 51% of the measurements.Conclusions:This study provides methodologically sound prescriptive standards and suggests that maternal body mass index is a determinant of a cutoff commonly used for decision-making.es_ES
Patrocinadordc.description.sponsorshipErasmus + Program of the European Union 2013-0040es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherKargeres_ES
Sourcedc.sourceFetal Diagnosis and Therapyes_ES
Keywordsdc.subjectCerebroplacental ratioes_ES
Keywordsdc.subjectColor Doppler ultrasonographyes_ES
Keywordsdc.subjectDoppler ultrasoundes_ES
Keywordsdc.subjectFetal growth restrictiones_ES
Keywordsdc.subjectNormality rangeses_ES
Títulodc.titlePrescriptive reference standards of third-trimester cerebroplacental ratio and its physiological determinantses_ES
Document typedc.typeArtículo de revistaes_ES
dcterms.accessRightsdcterms.accessRightsAcceso a solo metadatoses_ES
Catalogueruchile.catalogadorcfres_ES
Indexationuchile.indexArtículo de publicación ISIes_ES


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