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Authordc.contributor.authorOrioli, Ieda María 
Authordc.contributor.authorDolk, Helen 
Authordc.contributor.authorLópez Camelo, Jorge 
Authordc.contributor.authorGroisman, Boris 
Authordc.contributor.authorBenavides Lara, Adriana 
Authordc.contributor.authorGiménez, Lucas Gabriel 
Authordc.contributor.authorMattos Correa, Daniel 
Authordc.contributor.authorAscurra, Marta 
Authordc.contributor.authorAquino Bonilha, Eliana de 
Authordc.contributor.authorCanessa Tapia, María Aurora 
Authordc.contributor.authorAraújo de França, Giovanny Vinícius 
Authordc.contributor.authorHurtado Villa, Paula 
Authordc.contributor.authorIbarra Ramírez, Marisol 
Authordc.contributor.authorPardo, Rosa 
Authordc.contributor.authorPastora, Dania María 
Authordc.contributor.authorZarante, Ignacio 
Authordc.contributor.authorSchneider Soares, Flavia 
Authordc.contributor.authorMartínez de Carvalho, Flavia 
Authordc.contributor.authorPiola, Mariana 
Cita de ítemdc.identifier.citationAm J Med Genet. 2020;184C:1078–1091es_ES
Abstractdc.description.abstractThe early detection of congenital anomaly epidemics occurs when comparing current with previous frequencies in the same population. The success of epidemiologic surveillance depends on numerous factors, including the accuracy of the rates available in the base period, wide population coverage, and short periodicity of analysis. This study aims to describe the Latin American network of congenital malformation surveillance: ReLAMC, created to increase epidemiologic surveillance in Latin America. We describe the main steps, tasks, strategies used, and preliminary results. From 2017 to 2019, five national registries (Argentina [RENAC], Brazil [SINASC/SIM-BRS], Chile [RENACH], Costa Rica [CREC], Paraguay [RENADECOPY-PNPDC]), six regional registries (Bogotá [PVSDC-Bogota], Cali [PVSDC-Cali], Maule [RRMC SSM], Nicaragua [SVDC], Nuevo-León [ReDeCon HU], S~ao Paulo [SINASC/SIM-MSP]) and the ECLAMC hospital network sent data to ReLAMC on a total population of 9,152,674 births, with a total of 101,749 malformed newborns (1.1%; 95% CI 1.10–1.12). Of the 9,000,651 births in countries covering both live and stillbirths, 88,881 were stillborn (0.99%; 95% CI 0.98–0.99), and among stillborns, 6,755 were malformed (7.61%; 95% CI 7.44–7.79). The microcephaly rate was 2.45 per 10,000 births (95% CI 2.35–2.55), hydrocephaly 3.03 (2.92–3.14), spina bifida 2.89 (2.78–3.00), congenital heart defects 15.53 (15.27–15.79), cleft lip 2.02 (1.93–2.11), cleft palate and lip 2.77 (2.66–2.88), talipes 2.56 (2.46–2.67), conjoined twins 0.16 (0.14–0.19), and Down syndrome 5.33 (5.18–5.48). Each congenital anomaly showed heterogeneity in prevalence rates among registries. The harmonization of data in relation to operational differences between registries is the next step in developing the common ReLAMC database.es_ES
Patrocinadordc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) 440614/2016-3 310772/2017-6 424494/2016-7 465549/2014-4 Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) 88881.130724/2016-01 Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio De Janeiro (FAPERJ) E-26/202.617/2019 EUHorizon 2020 734584es_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.uri*
Sourcedc.sourceAmerican Journal of Medical Genetics Part C-Seminars in Medical Geneticses_ES
Keywordsdc.subjectCongenital anomalyes_ES
Keywordsdc.subjectDown syndromees_ES
Keywordsdc.subjectLatin Americaes_ES
Títulodc.titleThe Latin American network for congenital malformation surveillance: ReLAMCes_ES
Document typedc.typeArtículo de revistaes_ES
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Indexationuchile.indexArtículo de publicación ISIes_ES

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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile