Show simple item record

Authordc.contributor.authorPokrant, Ekaterina 
Authordc.contributor.authorYévenes, Karina 
Authordc.contributor.authorTrincado, Lina 
Authordc.contributor.authorTerraza, Gigliola 
Authordc.contributor.authorGalarce, Nicolás 
Authordc.contributor.authorAldo, Maddaleno 
Authordc.contributor.authorSan Martín Núñez, Betty 
Authordc.contributor.authorLapierre Acevedo, Lisette 
Authordc.contributor.authorCornejo Kelly, Javiera 
Admission datedc.date.accessioned2021-09-21T14:38:43Z
Available datedc.date.available2021-09-21T14:38:43Z
Publication datedc.date.issued2021
Cita de ítemdc.identifier.citationAnimals 2021, 11, 853es_ES
Identifierdc.identifier.other10.3390/ani11030853
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/182017
Abstractdc.description.abstractOxytetracycline (OTC) is widely used in broiler chickens. During and after treatment a fraction of OTC is excreted in its original form and as its epimer, 4-epi-OTC in droppings. To address the transfer of OTC into the environment, we evaluated the dissemination of OTC and 4-epi-OTC from treated birds to the environment and sentinels, through the simultaneous analysis of broiler droppings and litter. Male broiler chickens were bred in controlled conditions. One group was treated by orogastric tube with 80 mg kg−1 of OTC and two groups received no treatment (sentinels). OTC+4-epi-OTC were analyzed and detected by a HPLC-MS/MS post the end of treatment. The highest concentrations of OTC+4-epi-OTC were detected in the droppings of treated birds 14-days following the end of treatment (2244.66 µg kg−1 ), and one day following the end of treatment in the litter (22,741.68 µg kg−1 ). Traces of OTC+4-epi-OTC were detected in the sentinels’ droppings and litter (<12.2 µg kg−1 ). OTC+4-epi-OTC can be transferred from treated birds to the environment and to other untreated birds. The presence and persistence of OTC+4-epi-OTC in litter could contribute to the selection of resistant bacteria in the environment, increasing the potential hazard to public and animal health.es_ES
Patrocinadordc.description.sponsorshipVicerrectoria de Investigacion y Desarrollo (VID) VID2019 ENL07/19 International Atomic Energy Agency 22180 (D52041) Doctorado Nacional Conicyt 21180769es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherMDPIes_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Sourcedc.sourceAnimalses_ES
Keywordsdc.subjectOxytetracyclinees_ES
Keywordsdc.subject4-epi-Oxytetracyclinees_ES
Keywordsdc.subjectPoultry droppingses_ES
Keywordsdc.subjectPoultry litteres_ES
Keywordsdc.subjectBroiler chickenes_ES
Keywordsdc.subjectHPLC-MS/MSes_ES
Keywordsdc.subjectAntibiotic disseminationes_ES
Keywordsdc.subjectSentinel birdses_ES
Títulodc.titleEvaluation of antibiotic dissemination into the environment and untreated animals, by analysis of oxytetracycline in poultry droppings and litteres_ES
Document typedc.typeArtículo de revistaes_ES
Catalogueruchile.catalogadorcrbes_ES
Indexationuchile.indexArtículo de publicación ISIes_ES


Files in this item

Icon

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile