Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 37361-37380 of 98971

    • Effect of left intraventricular pressure on magnitude of vascular waterfall in the epicardial coronary veins 
      Domenech Lira, Raúl; Macho Fisher, Pilar; Barros, Felipe (Oxford University Press, 1990)
      Study objective - The aim was to test the hypothesis of a vascular waterfall in the epicardial veins due to compression by the left ventricular (LV) pressure. If this were so, the epicardial venous pressure should be a ...
    • Catechol-mediated effects of harmaline on the action potential of rat atrial fibres 
      Carpentier,; Narvarte,; Sanhueza, (Oxford University Press, 1977)
      Summary: The mechanism of the transient enhancement of the amplitude of the action potential (AAP) induced by harmaline (HME) was studied in rat atria. The results show that HME increases AAP through an enhancement of the ...
    • Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ... 
      Andaur, Rodrigo; Tapia, Julio C.; Moreno, José; Soto, Leopoldo; Armisen, Ricardo; Marcelain Cubillos, Katherine (Impact Journals LLC, 2018)
      © Andaur et al. Enhanced radiosensitivity at low doses of ionizing radiation (IR) (0.2 to 0.6 Gy) has been reported in several cell lines. This phenomenon, known as low doses hyperradiosensitivity (LDHRS), appears as an ...
    • miR15a and miR16 in Chilean type 1 diabetes patients: possible association with apoptosis, inflammatory, ... 
      García Díaz, Diego; Camacho-Guillén, Patricia; Codner Dujovne, Ethel; Pérez Bravo, Francisco (Springer International Publishing, 2018)
      © 2018 Italian Society of Endocrinology (SIE) Aim: Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the progressive destruction of β cells, mediated by the interaction between T cells and several ...
    • Implementación de la política pública para el cuidado de la primera infancia en el contexto chileno: Una ... 
      González-Burboa, Alexis; Miranda-Valdebenito, Nazaryh; Vera-Calzaretta, Aldo; Arteaga Herrera, Oscar (Universidad Nacional de Colombia, 2017)
      © 2017, Universidad Nacional de Colombia. All rights reserved. In the field of childhood care, Chile has a long history of interventions which have pointed to reduce infant mortality, most of them with a strong biomedical ...
    • Oxygen uptake kinetics to assess cardiorespiratory fitness in obese patients Uso de la cinética del consumo ... 
      Montero Miranda, Claudia; Ibacache, Paulina; Opazo, Edgardo; Vásquez Rojas, Juan Rodrigo; Cano, Marcelo (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Background: The evaluation of cardiorespiratory fitness (RCC) using maximal or peak oxygen consumption (VO2), requires a high level of effort in obese patients. We ...
    • Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer ... 
      Chennamadhavuni, Divya; Saavedra-Avila, Noemi Alejandra; Carreño, Leandro J.; Guberman-Pfeffer, Matthew J.; Arora, Pooja; Yongqing, Tang; Koay, Hui Fern; Godfrey, Dale I.; Keshipeddy, Santosh; Richardson, Stewart K.; Sundararaj, Srinivasan; Lo, Jae Ho; Wen, Xiangshu; (Elsevier Ltd, 2018)
      © 2018 Elsevier Ltd Glycosylceramides that activate CD1d-restricted invariant natural killer T (iNKT) cells have potential therapeutic applications for augmenting immune responses against cancer and infections. Previous ...
    • A changing etiologic scenario in liver transplantation for hepatocellular carcinoma in a multicenter cohort ... 
      Piñero, Federico; Costa, Paulo; Boteon, Yuri Longatto; Duque, Sergio Hoyos; Marciano, Sebastian; Anders, Margarita; Varón, Adriana; Zerega, Alina; Poniachik Teller, Jaime; Soza, Alejandro; Padilla Machaca, Martín; Menéndez, Josemaría; Zapata, Rodrigo; Vilatoba, Mario; Muñoz Muñoz, E. C. (Elsevier Masson SAS, 2018)
      © 2018 Elsevier Masson SASBackground and aim: Non-alcoholic fatty liver disease (NAFLD) is an increasing cause of hepatocellular carcinoma (HCC) and liver transplantation (LT). Our study focused on changing trends of liver ...
    • Changes in socio-economic level and their impact on nutritional status: A follow-up study among young Chilean ... 
      Amigo, Hugo; Vásquez, Alejandra; Bustos, Patricia (Cambridge University Press, 2018)
      Copyright © The Authors 2018. Objective To verify the association between changes in socio-economic level (SEL) and nutritional status of Chilean adults over a 10-year period.Design Concurrent cohort study.Setting/Subjects ...
    • O6-methylguanine-DNA-methyltransferase (MGMT) expression in patients with glioblastoma multiforme Expresión ... 
      Jiménez, Daniel; Matamala, José Manuel; Chiti, Alessandra; Vergara, Carmen; Tissera, Claudia; Melo, Rómulo; Cartier Rovirosa, Luis (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Background: Patients with Glioblastoma multiforme (GBM) have a five years survival of less than 5%, but the response to chemotherapy with alkylating agents can vary ...
    • Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units Cardiotoxicidad ... 
      Hameau, Rene; Gabrielli, Luigi; Garrido, Marcelo; Guzmán, Ana María; Retamal, Ignacio; Vacarezza, María José; Greig, Douglas; Ocqueteau, Mauricio; Sánchez, César; Pizarro, Marcela; Corvalán, Alejandro; Lavandero González, Sergio; Castro, Pablo F.; Martínez, Gonzalo (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, ...
    • Prescription of opioids at the moment of discharge from an emergency department Prescripción de opioides ... 
      Martínez, Matías; Herrada, Luis; Torres Muñoz, Ana Camila; Chávez,; Jirón Aliste, Marcela (Sociedad Medica de Santiago, 2017)
      © 2017, Sociedad Medica de Santiago. All rights reserved. Background: There is a worrisome increase in opioid prescription worldwide. Their use and overuse may cause adverse outcomes. Aim: To determine incidence and ...
    • The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels 
      García, Isaac E.; Villanelo, Felipe; Contreras, Gustavo F.; Pupo, Amaury; Pinto, Bernardo I.; Contreras, Jorge E.; Pérez Acle, Tomás; Alvarez, Osvaldo; Latorre, Ramón; Martínez, Agustín D.; González, Carlos (Rockefeller University Press, 2018)
      Mutations in connexin 26 (Cx26) hemichannels can lead to syndromic deafness that affects the cochlea and skin. These mutations lead to gain-of-function hemichannel phenotypes by unknown molecular mechanisms. In this study, ...
    • Study of Ras/MAPK pathway gene variants in Chilean patients with Cryptorchidism 
      Rodríguez, F.; Vallejos, C.; Ponce, D.; Unanue, N.; Hernández, M. I.; Célis, S.; Arcos, K.; Belmar, F.; López, M. T.; Cassorla Goluboff, Fernando (Blackwell Publishing Ltd, 2018)
      © 2018 American Society of Andrology and European Academy of AndrologyCryptorchidism is one of the most common congenital disorders in boys, and several genetic, hormonal, and environmental factors have been proposed as ...
    • LGA-newborn from patients with pregestational obesity present reduced adiponectin-mediated vascular relaxation ... 
      Muñoz Muñoz, Estefanía del Carmen; Krause, Bernardo J.; Uauy Dagach-Imbarack, Ricardo; Casanello, Paola (Wiley-Liss Inc., 2018)
      © 2018 Wiley Periodicals, Inc. Maternal obesity is associated with large-for-gestational-age (LGA) neonates and programming of obesity-related cardiovascular disease in the offspring, however, the mechanisms that lead to ...
    • The acoustic adaptation hypothesis in a widely distributed South American frog: Southernmost signals propagate ... 
      Velásquez, Nelson A.; Moreno Gómez, Felipe N.; Brunetti, Enzo; Penna Varela, Mario (Nature Publishing Group, 2018)
      © 2018 The Author(s).Animal communication occurs in environments that affect the properties of signals as they propagate from senders to receivers. We studied the geographic variation of the advertisement calls of male ...
    • Oxidative stress in female cancers 
      Calaf, Gloria M.; Urzúa Tobar, Ulises; Termini, Lara; Aguayo, Francisco (Impact Journals LLC, 2018)
      © Calaf et al. Breast, cervical and ovarian cancers are highly prevalent in women worldwide. Environmental, hormonal and viral-related factors are especially relevant in the development of these tumors. These factors are ...
    • Hospitalizations for asthma exacerbation in Chilean children: A multicenter observational study 
      Herrera, A. M.; Brand, P.; Cavada, G.; Koppmann, A.; Rivas, M.; Mackenney, J.; Sepúlveda, H.; Wevar, M. E.; Cruzat, L.; Soto, S.; Pérez, M. A.; León, A.; Contreras, I.; Alvarez, C.; Walker, B.; Flores, C.; Lezana, V.; Garrido, C.; Herrera, M. E.; Rojas, A.; Andrades, C.; Chal (Elsevier Doyma, 2018)
      © 2018 SEICAPBackground: Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. Objective: Describe clinical characteristics of ...
    • Multiple primary malignant neoplasms detected by PET/CT in cancer patients Cáncer sincrónico y metacrónico ... 
      Ladrón De Guevara, David; Quera, Rodrigo; Rozas, Sebastián; Schacher, Shmuel; Reyes, José Miguel; Pardo, Claudio; Pefaur, Raúl (Sociedad Medica de Santiago, 2017)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Background: Imaging with F18-fluorodeoxyglucose PET/CT is used to determine sites of abnormal glucose metabolism and can be used to characterize and localize many ...
    • Revisiting the role of TRP, orai, and ASIC channels in the pulmonary arterial response to hypoxia 
      Reyes, Roberto V.; Castillo Galán, Sebastián; Hernández, Ismael; Herrera, Emilio A.; Ebensperger Darrouy, Germán; Llanos Mansilla, Jorge (Frontiers Media S.A., 2018)
      © 2018 Reyes, Castillo-Galán, Hernandez, Herrera, Ebensperger and Llanos. The pulmonary arteries are exquisitely responsive to oxygen changes. They rapidly and proportionally contract as arterial PO2 decrease, and they ...