Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 37981-38000 of 98671

    • Aerosol effects on the UV irradiance in Santiago de Chile 
      Cordero, R. R.; Seckmeyer, G.; Damiani, A.; Jorquera, J.; Carrasco, J.; Muñoz, R.; Da Silva, L.; Labbe, F.; Laroze, D. (Elsevier Ltd, 2014)
      Santiago de Chile (33°27' S-70°41' W) is a mid-latitude city of 6 million inhabitants with a complicated surrounding topography. Aerosol extinction in Santiago is determined by the semi-arid local climate, the urban ...
    • Ovarian morphometry and mRNA expression of antimullerian hormone (AMH), follicle stimulating hormone receptor ... 
      Rojas García, Pedro; Recabarren, M. P.; Palma, S.; Maliqueo Yevilao, Manuel; Carrasco, A.; Sir Petermann, Teresa; Recabarren, S. E. (Universidad Austral de Chile, 2014)
      Antenatal exposure to testosterone (T) has a series of consequences on postnatal reproductive parameters in females of several animal species. In sheep born under this condition the ovaries are characterized by an increased ...
    • Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates ... 
      Elisa Kallio, K. A.; Marchesani, Marja; Vlachopoulou, Efthymia; Mäntylä, Päivi; Paju, Susanna; Buhlin, Kåre; Suominen, Anna L.; Contreras, Johanna; Knuuttila, Matti; Hernandez, Marcela; Huumonen, Sisko; Nieminen, Markku S.; Perola, Markus; Sinisalo, Juha; Lokki, Marja (American Society for Microbiology, 2014)
      Periodontitis is a chronic inflammatory disease with a multifactorial etiology. We investigated whether human major histocompatibility complex (MHC) polymorphisms (6p21.3) are associated with periodontal parameters. Parogene ...
    • Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance 
      Troncoso, Rodrigo; Paredes, Felipe; Parra, Valentina; Gatica, Damián; Vásquez Trincado, César Alonso; Quiroga, Clara; Bravo Sagua, Roberto; López Crisosto, Camila; Rodriguez, Andrea E.; Oyarzún, Alejandra P.; Kroemer, Guido; Lavandero González, Sergio (Taylor and Francis Inc., 2014)
      Glucocorticoids, such as dexamethasone, enhance protein breakdown via ubiquitin-proteasome system. However, the role of autophagy in organelle and protein turnover in the glucocorticoid-dependent atrophy program remains ...
    • The placental pursuit for an adequate oxidant balance between the mother and the fetus 
      Herrera, Emilio A.; Krause, Bernardo; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Casanello, Paola; Parra Cordero, Mauro; Llanos Mansilla, Jorge (Frontiers Research Foundation, 2014)
      The placenta is the exchange organ that regulates metabolic processes between the mother and her developing fetus. The adequate function of this organ is clearly vital for a physiologic gestational process and a healthy ...
    • Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa 
      Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P.; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V.; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M.; (Wiley-Liss Inc., 2014)
      Knockout models have shown that the coagulation system has a role in vascular development and angiogenesis. Herein, we report for the first time that zymogen FX and its active form (FXa) possess anti-angiogenic properties. ...
    • Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells 
      Li, Q.; Zhu, X.; Ishikura, S.; Zhang, D.; Gao, J.; Sun, Y.; Contreras Ferrat, Ariel Eduardo; Foley, K. P.; Lavandero González, Sergio; Yao, Z.; Bilan, Philip J.; Klip, Amira; Niu, W. (American Physiological Society, 2014)
      Elevating cytosolic Ca2+ stimulates glucose uptake in skeletal muscle, but how Ca2+ affects intracellular traffic of GLUT4 is unknown. In tissue, changes in Ca2++ leading to contraction preclude analysis of the impact of ...
    • Diet of phytotoma rutila (Passeriformes: Cotingidae) in the central Monte desert, Argentina Dieta de phytotoma ... 
      Ríos, Juan Manuel; Zarco, Agustín; Mosca Torres, María E.; Sabat Kirkwood, Alejandro Pablo (Universidad de Concepcion, 2014)
      Botanical composition of the diet of White-tipped Plantcutter Phytotoma rutila in the central Monte desert from Argentina, was determined by microhistological analysis of excreta. In both sexes, the diet was composed by a ...
    • A structural view of ligand-dependent activation in thermoTRP channels 
      Steinberg, Ximena; Lespay-Rebolledo, Carolyne; Brauchi, Sebastian (Frontiers Research Foundation, 2014)
      Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped into seven sub-families. Although great advances have been made regarding the activation and modulation of TRP channel activity, ...
    • Scleromyxedema without paraproteinemia 
      Abarzúa, Alvaro A.; Giesen, Laura F.; Sandoval, Mauricio O.; González, Sergio B. (Blackwell Publishing Ltd, 2014)
      Background: Scleromyxedema is a rare generalized form of lichen myxedematosus, a chronic cutaneous mucinosis of unknown etiology usually associated with a monoclonal gammopathy and underlying systemic disorders. It is ...
    • Southern annular mode-like changes in southwestern Patagonia at centennial timescales over the last three millennia 
      Moreno Moncada, Patricio; Vilanova, I.; Villa Martínez, Rodrigo; Garreaud Salazar, René; Rojas, M.; De Pol-Holz, Ricardo (Nature Publishing Group, 2014)
      Late twentieth-century instrumental records reveal a persistent southward shift of the Southern Westerly Winds during austral summer and autumn associated with a positive trend of the Southern Annular Mode (SAM) and ...
    • Copy number variants in patients with short stature 
      Van Duyvenvoorde, Hermine A.; Lui, Julian C.; Kant, Sarina G.; Oostdijk, Wilma; Gijsbers, Antoinet C.J.; Hoffer, Mariëtte J.V.; Karperien, Marcel; Walenkamp, Marie J.E.; Noordam, Cees; Voorhoeve, Paul G.; Mericq, Verónica; Pereira, Alberto M.; Claahsen-Van De Grinten (Nature Publishing Group, 2014)
      Height is a highly heritable and classic polygenic trait. Recent genome-wide association studies (GWAS) have revealed that at least 180 genetic variants influence adult height. However, these variants explain only about ...
    • The referendum in Latin America: An analysis from a comparative law approach El referéndum en Latinoamérica: ... 
      Soto Barrientos, Francisco (Universidad Nacional Autonoma de Mexico, 2013)
      This paper tells of the proliferation in recent decades, formulas referendums in Latin American constitutions. The comparative analysis of this mechanism to identify severalunique features in the treatment of this formula ...
    • Recommendations of the ethics committee of the Chilean Society of Nephrology for the management of ethical ... 
      Vukusich, Antonio; Catoni, María Isabel; Salas, Sofía P.; Valdivieso, Andrés; Roessler, Emilio (Sociedad Medica de Santiago, 2014)
      There are different approaches to treat patients with End Stage Renal Disease (ESRD): hemodialysis, peritoneal dialysis, renal transplantation and conservative medical management. The choice of the best therapy for each ...
    • Association between genetic polymorphisms of interleukin 6 (IL6), IL6R and IL18 with metabolic syndrome in ... 
      Suazo, José; Smalley, Susan Valerie; Hodgson, María Isabel; Weisstaub, Gerardo; González, Andrea; Santos, José Luis (Sociedad Medica de Santiago, 2014)
      Background: Metabolic Syndrome (MS) is highly prevalent among obese children and adolescents and is considered a predictor for the development of type 2 diabetes mellitus and cardiovascular disease. Obesity is associated ...
    • Gene geography of Chile. Regional distribution of American, European and African genetic contributions ... 
      Fuentes, Macarena; Pulgar, Iván; Gallo, Carla; Bortolini, María Cátira; Canizales-Quinteros, Samuel; Bedoya, Gabriel; González-José, Rolando; Ruiz-Linares, Andrés; Rothhammer Engel, Francisco (Sociedad Medica de Santiago, 2014)
      Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
    • Impact beyond the objectives: A qualitative study of a faculty development program in medical education ... 
      Moore, Philippa; Montero, Luz; Triviño, Ximena; Sirhan, Marisol; Leiva, Loreto (Sociedad Medica de Santiago, 2014)
      Background: In medical education there has been increasing emphasis on faculty development programs aimed at the professionalization of teaching and increasing students' learning. However, these programs have been shown ...
    • A role for the endocannabinoid system in hepatic steatosis Sistema endocanabinoide y desarrollo de esteatosis ... 
      Valenzuela, Carina; Castillo, Valeska; Ronco Macchiavello, Ana María; Aguirre, Carolina; Hirsch Birn, Sandra; Llanos Silva, Miguel (Sociedad Medica de Santiago, 2014)
      The endocannabinoid system (SEC) is an important modulator of several metabolic functions. This system is composed by cannabinoid receptors type 1 and 2 (RCB1 and RCB2), their endogenous ligands, known as endocannabinoids, ...
    • A performance/cost evaluation for a GPU-based drug discovery application on volunteer computing 
      Guerrero, Ginés D.; Imbernón, Baldomero; Pérez-Sánchez, Horacio; Sanz, Francisco; García, José M.; Cecilia, José M. (Hindawi Publishing Corporation, 2014)
      Bioinformatics is an interdisciplinary research field that develops tools for the analysis of large biological databases, and, thus, the use of high performance computing (HPC) platforms is mandatory for the generation of ...
    • Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system 
      Ocaranza, María Paz; Michea Acevedo, Luis; Chiong Lay, Mario; Lagos, Carlos F.; Lavandero González, Sergio; Jalil Milad, Jorge (Portland Press Ltd, 2014)
      Chronic RAS (renin-angiotensin system) activation by both AngII (angiotensin II) and aldosterone leads to hypertension and perpetuates a cascade of pro-hypertrophic, pro-inflammatory, pro-thrombotic and atherogenic effects ...