Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 38021-38040 of 98076

    • Global climate evolution during the last deglaciation 
      Clark, Peter U.; Shakun, Jeremy D.; Baker, Paul A.; Bartlein, Patrick J.; Brewer, Simon; Brook, Ed; Carlson, Anders E.; Cheng, Hai; Kaufman, Darrell S.; Liu, Zhengyu; Marchitto, Thomas M.; Mix, Alan C.; Morrill, Carrie; Otto-Bliesner, Bette L.; Pahnke, Katharina; Russel (2012)
      Deciphering the evolution of global climate from the end of the Last Glacial Maximum approximately 19 ka to the early Holocene 11 ka presents an outstanding opportunity for understanding the transient response of Earth's ...
    • Metabolic effect of metformin in obese adolescents at risk of diabetes mellitus type 2 Efecto metabólico ... 
      Bernardita Prado, Alcalde; Verónica Gaete, P.; Francisca Corona, H.; Eldreth Peralta, V.; Paula Donoso, A.; Ximena Raimann, T. (2012)
      In adults, metformin promotes weight loss and prevents the development of type 2 diabetes mellitus (DM2). However, these effects have not been demonstrated in adolescents at risk for DM2. Objective: To analyze the ...
    • Persistent interstitial pulmonary emphysema in the newborn: Clinical case Enfisema pulmonar intersticial ... 
      German Mühlhausen, M.; Scarlett Brethauer, M.; Fernando Martínez, R.; Yorky Melipillán, A. (2012)
      Persistent Interstitial Pulmonary Emphysema (PIPE) is a syndrome characterized by air leak to the perivascular tissue in the lung, affecting newborns with history of mechanical ventilation. It is also characterized by lack ...
    • Sonography in pathologies of scalp and hair 
      Wortsman, Ximena; Wortsman, J.; Matsuoka, L.; Saavedra, T.; Mardones, F.; Saavedra, D.; Guerrero, R.; Corredoira, Y. (2012)
      Disorders of the scalp often result in severe cosmetic interference with quality of life, creating the need for optimal medical surveillance. We tested the latest generation of ultrasound machines in patients with scalp ...
    • Merkel cell polyomavirus in non-small cell lung carcinomas from Chile 
      Gheit, Tarik; Muñoz, Juan Pablo; Levican, Jorge; González, Carolina; Ampuero Llanos, Sandra; Parra, Bárbara; Gaggero Brillouet, Aldo; Corvalán, Alejandro H.; Uribe Meneses, Manuel Ángel; Tommasino, Massimo; Aguayo, Francisco (2012)
      Lung cancer is a leading pathology strongly associated with the smoking habit. However, a viral etiology for a subset of patients developing lung cancer has been suggested. Polyomaviruses (PyVs) are small double stranded ...
    • Persistent oxytetracycline exposure induces an inflammatory process that improves regenerative capacity in ... 
      Barros-Becker, Francisco; Romero Ormazábal, Jaime; Pulgar, Alvaro; Feijóo, Carmen G. (2012)
      Background: The excessive use of antibiotics in aquaculture can adversely affect not only the environment, but also fish themselves. In this regard, there is evidence that some antibiotics can activate the immune system ...
    • TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the ... 
      Rojas Rivera, Diego; Armisen Yáñez, Ricardo; Colombo, A.; Martínez, G.; Eguiguren, A. L.; Díaz, A.; Kiviluoto, S.; Rodríguez, D.; Patron, M.; Rizzuto, R.; Bultynck, G.; Concha Nordemann, Miguel; Sierralta, J.; Stutzin Schottlander, Andrés; Hetz Flores, Claudio (2012)
      Transmembrane BAX inhibitor motif-containing (TMBIM)-6, also known as BAX-inhibitor 1 (BI-1), is an anti-apoptotic protein that belongs to a putative family of highly conserved and poorly characterized genes. Here we report ...
    • Women's education level, maternal health facilities, abortion legislation and maternal deaths: A natural ... 
      Koch, Elard; Thorp, John; Bravo, Miguel; Gatica, Sebastián; Romero, Camila X.; Aguilera, Hernán; Ahlers, Ivonne (2012)
      Background: The aim of this study was to assess the main factors related to maternal mortality reduction in large time series available in Chile in context of the United Nations’ Millennium Development Goals (MDGs). Methods: ...
    • Studying neonates' language and memory capacities with functional near-infrared spectroscopy 
      Benavides-Varela, Silvia; Gómez, David M.; Mehler, Jacques (2011)
      The measurement of newborns' brain hemodynamic activity has improved our understanding of early cognitive processes, in particular of language acquisition. In this paper, we describe two experimental protocols adapted to ...
    • Thiophene- and silarylene-containing polyesters. Resonance effect on conductivity after polarization in an ... 
      González-Henríquez, Carmen M.; Tagle, Luis H.; Terraza, Claudio A.; Leiva, Ángel; Barriga González, Andrés Antonio; Volkmann, Ulrich G.; Cabrera, Alejandro L.; Ramos-Moore, Esteban; Pavez-Moreno, Maximiliano (2012)
      Polyesters were synthesized by direct polycondensation of thiophene-2,5-dicarboxylic acid and five different silarylene-containing diphenols using a tosyl chloride/pyridine/N,N-dimethylformamide system as a condensing ...
    • Objective vs. self-reported physical activity and sedentary time: Effects of measurement method on relationships ... 
      Celis Morales, Carlos; Pérez Bravo, Francisco; Ibañez, Luis; Salas, Carlos; Bailey, Mark E.S.; Gill, Jason M.R. (2012)
      Purpose: Imprecise measurement of physical activity variables might attenuate estimates of the beneficial effects of activity on health-related outcomes. We aimed to compare the cardiometabolic risk factor dose-response ...
    • Altered prion protein expression pattern in CSF as a biomarker for creutzfeldt-jakob disease 
      Torres, Mauricio; Cartier Rovirosa, Luis; Matamala, José Manuel; Hernández, Nancy; Woehlbier, Ute; Hetz Flores, Claudio (2012)
      Creutzfeldt-Jakob disease (CJD) is the most frequent human Prion-related disorder (PrD). The detection of 14-3-3 protein in the cerebrospinal fluid (CSF) is used as a molecular diagnostic criterion for patients clinically ...
    • Enteric viruses in wastewaters: An interesting approach to evaluate the potential impact of rotavirus ... 
      O'Ryan Gallardo, Miguel; Lucero, Yalda; Vidal, Roberto (2012)
      Rotavirus and norovirus are the leading causes of acute gastroenteritis worldwide. Both viruses share features such as low infectious dose, high stool concentration and prolonged survival in the environment, including ...
    • The antioxidant N-acetylcysteine prevents the mitochondrial fragmentation induced by soluble amyloid-β ... 
      Sanmartin, C. D.; Adasme, T.; Hidalgo, C.; Paula-Lima, A. C. (2012)
      Background: Soluble amyloid-β peptide oligomers (AβOs), which are centrally involved in the pathogenesis of Alzheimer's disease, trigger Ca 2+ influx through N-methyl-D-aspartate receptors and stimulate reactive oxygen ...
    • Olfactory deficits and cognitive dysfunction in Parkinson's disease 
      Parrao, Teresa; Chana, Pedro; Venegas, Pablo; Behrens Pellegrino, María Isabel; Aylwin, María Luz (2012)
      Background: Olfactory deficits and executive dysfunction have been reported in Parkinson's disease (PD). However, the association between these deficits has not been thoroughly examined. Methods: We studied 44 PD subjects ...
    • Pleural empyema. Retrospective review of 343 patients Empiema pleural en 343 casos con tratamiento quirúrgico: ... 
      González L., Roberto; Prats M., Rafael; Lazo P., David; Jadue T, Andrés; Mordojovich, Gerardo; Santolaya Cohen, Raimundo; Rodríguez D., Patricio (2012)
      Background: Pleural empyema still has a dismal prognosis. Aim: To describe features and prognostic factors of patients with pleural empyema subjected to surgical procedures. Material and Methods: Retrospective review of ...
    • Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory ... 
      Miranda, Hugo F.; Romero, Maria Asunción; Puig, Margarita M. (2012)
      Preclinical studies have demonstrated antinociceptive synergism between dexketoprofen (DEX) and tramadol (TRM) in acute animal models of nociception. The aim of the present study was to investigate the type of interaction ...
    • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome ... 
      Muñoz, Patricia; Paris Pizarro, Irmgard; Sanders, Laurie H.; Greenamyre, J. Timothy; Segura Aguilar, Juan (2012)
      We tested the hypothesis that both VMAT-2 and DT-diaphorase are an important cellular defense against aminochrome-dependent neurotoxicity during dopamine oxidation. A cell line with VMAT-2 and DT-diaphorase over-expressed ...
    • Increased production of soluble TLR2 by lamina propria mononuclear cells from ulcerative colitis patients 
      Candia, Enzo; Díaz Jiménez, David; Langjahr, Patricia; Núñez, Lucía E.; Fuente, Marjorie de la; Farfán, Nancy; López Kostner, Francisco; Abedrapo Moreira, Mario Antonio; Alvarez Lobos, Manuel; Pinedo, George; Beltrán, Caroll J.; González, Carlos; González Burgos, María Julieta; Quera Pino, Rodrigo (2012)
      Toll-like receptor 2 (TLR2) is a type I pattern recognition receptor that has been shown to participate in intestinal homeostasis. Its increased expression in the lamina propria has been associated with the pathogenesis ...
    • Structural characterization of microcin E492 amyloid formation: Identification of the precursors 
      Arranz, Rocío; Mercado, Gabriela; Martín-Benito, Jaime; Giraldo, Rafael; Monasterio Opazo, Octavio; Lagos Mónaco, Rosalba; Valpuesta, José M. (2012)
      Microcin E492 is a low-molecular weight, channel-forming bacteriotoxin that generates amyloid structures. Using electron microscopy and image processing techniques several structural conformations can be observed. Prior ...