Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 38321-38340 of 97836

    • Genetic and environmental influences on ethanol consumption: Perspectives from preclinical research 
      Pautassi, Ricardo M.; Camarini, Rosana; Quadros, Isabel Marian; Miczek, Klaus A.; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2010)
      Background: Alcohol use disorders (abuse and dependence, AUD) are multifactorial phenomena, depending on the interplay of environmental and genetic variables. Method: This review describes current developments in animal ...
    • Ovarian and inferior vena cava thrombosis with associated puerperal endometritis Trombosis de vena ovárica ... 
      Palavecino, Tamara; Torres, Raúl; Quinteros, Nancy; Salinas, Hugo (2010)
      Ovarian vein thrombosis is a rare and severe puerperal complication that usually manifests as fever and abdominal pain in the puerperal period and is more frequent in women who have undergone cesarean section. There is an ...
    • Early life and adult socioeconomic influences on mortality risk: Preliminary Report of a 'Pauper Rich' ... 
      Koch, Elard; Romero, Tomás; Romero, Camila X.; Aguilera, Hernán; Paredes, Mario; Vargas, Miguel; Ahumada, Carlos (2010)
      Purpose: The inverse relationship between early life and adult socioeconomic measures and mortality risk has been well established in developed countries, but remains practically unexplored in Latin American societies. The ...
    • The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the biological treatment ... 
      Thibaut, Florence; Barra, Flora De La; Gordon, Harvey; Cosyns, Paul; Bradford, John M.W. (2010)
      Objectives. The primary aim of these guidelines was to evaluate the role of pharmacological agents in the treatment and management of paraphilia, with a focus on the treatment of adults males. Because such treatments are ...
    • Oral care and dental management for patients with epidermolysis bullosa 
      Krämer, Susanne M. (2010)
      Dental treatment is an important part of the multidisciplinary care of patients with epidermolysis bullosa (EB). Routine dental treatment can be difficult to provide in patients with severe tissue fragility caused by mucosal ...
    • Comparison of the clinical efficacy of two different immunosuppressive regimens in patients with chronic ... 
      Cuchacovich, Miguel; Solanes, Federica; Estay Díaz, Gonzalo; Cermenati, Tomás; Avila, Samuel; Verdaguer, Juan; Verdaguer, Juan Ignacio; Carpentier, Cristian; Stopel, Juan; Rojas, Basilio; Traipe, Leonidas; Gallardo, Patricia; Sabugo, Francisca; Zanoli, Mario; Merino, Guiller (2010)
      Purpose: To prospectively compare 2 immunosupressive regimens in patients with active Vogt-Koyanagi-Harada disease in spite of systemic glucocorticoid treatment. Methods: Forty-four patients were diagnosed between 1998 and ...
    • Analysis of the opioid-opioid combinations according to the nociceptive stimulus in mice 
      Romero, Asunción; Miranda, Hugo F.; Puig, Margarita M. (2010)
      The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine, when two of them were systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid ...
    • Crossed testicular ectopia 
      Pinto, Carolina Whittle; Toro, Roberto Cabrera; Mansilla, Karina Hermosilla; Castro, Tirza Aguayo; Fuente-Alba, Claudio Silva (John Wiley and Sons Ltd, 2010)
      Crossed testicular ectopia is a low-prevalence entity. It consists of a congenital abnormality in which both testicles are located in the same inguinal cord or scrotal sac with independent irrigation. It may be suspected ...
    • The association between HLA DQ genetic polymorphism and type 1 diabetes 
      Mimbacas, Adriana; Pérez Bravo, Fernando; Santos, José; Pisciottano, Carmen; Grignola, Rosario; Javiel, Gerardo; Jorge, Ana; Cardoso, Horacio (2004)
      Susceptibility to the type 1 diabetes is genetically controlled and there is an increased risk associated with the presence of some specific alleles of the human leukocyte antigens class II loci (DQA1 and DQB1 genes). The ...
    • Benign tumors and pseudotumors of the Nail: A novel application of sonography 
      Wortsman, Ximena; Wortsman, Jacobo; Soto, Rosamary; Saavedra, Tirza; Honeyman Mauro, Juan; Sazunic,; Corredoira, Yamile (John Wiley and Sons Ltd, 2010)
      Objective. The purpose of this study was to determine the scope of high-resolution sonography in the detection of benign tumors and pseudotumors of the nail unit. Methods.We performed a retrospective study of the sonographic ...
    • Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism 
      Letelier, María Eugenia; Jara Sandoval, José; Molina Berríos, Alfredo Enrique; Faúndez, Mario; Aracena-Parks, Paula; Aguilera, Felipe (2010)
      Melatonin, an endogenous hormone, is used as an antioxidant drug in doses quite higher than the endogenous circulating levels of this hormone. Hepatic endoplasmic reticulum contains the cytochrome P450 (CYP450) system, ...
    • Synergism between COX-3 inhibitors in two animal models of pain 
      Muñoz, J.; Navarro, C.; Noriega, V.; Pinardi,; Sierralta, F.; Prieto, J. C.; Miranda, H. F. (2010)
      Objective and design: The antinociception induced by the intraperitoneal coadministration in mice of combinations of metamizol and paracetamol was evaluated in the tail flick test and orofacial formalin test. Methods: The ...
    • Effect of dietary intake on the levels of biliary unsaturated free fatty acids having inhibitory activity ... 
      Serra, Iván; Tsuchiya, Yasuo; Hori, Yasushi; Nakamura, Kazutoshi; Villegas, Rodrigo; Oyama, Mari; Makiguchi, Tomoo; Yamamoto, Masaharu (Asian Pacific Organization for Cancer Prevention, 2009)
      Unsaturated free fatty acids (FFAs), such as palmitoleic, oleic, linoleic, linolenic and arachidonic acids, have inhibitory actions on mutagenesis. These FFAs in bile may play a role in preventing cholecystopathy and their ...
    • Comparative effects of superoxide anion and hydrogen peroxide on microsomal and cytosolic glutathione ... 
      Letelier, María Eugenia; Molina Berríos, Alfredo Enrique; Cortés-Troncoso, Juan; Jara Sandoval, José; Müller, Andrea; Aracena Parks, Paula (2010)
      Glutathione S-transferases (GSTs) are isoenzymes occurring in the cytoplasm and as integral membrane proteins. In addition to their role in drug metabolism by conjugating electrophilic and lipophilic compounds with glutathione ...
    • Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to ... 
      Ewert, Patricia; Aguilera, Sergio; Alliende, Cecilia; Kwon, Yoon Jeoung; Albornoz, Amelina; Molina, Claudio; Urzúa, Ulises; Quest, Andrew F. G.; Olea, Nancy; Pérez, Paola; Castro, Isabel; Barrera, María José; Romo, Rafael; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Mar (2010)
      Objective. Disorganization of acinar cell apical microvilli and the presence of stromal collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is impaired in patients with Sjögren's ...
    • Influence of estrogens on copper indicators: In vivo and in vitro studies 
      Arredondo, Miguel; Núñez, Héctor; López, Guadalupe; Pizarro Aguirre, Fernando; Ayala, Mariana; Araya, Magdalena (2010)
      Classic copper indicators are not sensitive and specific for detecting excess copper exposure when this is higher than customary but not markedly elevated. Serum copper and ceruloplasmin (Cp) are the most commonly used ...
    • Spectrum of MLH1 and MSH2 mutations in Chilean Families with suspected Lynch syndrome 
      Alvarez, Karin; Hurtado, Claudia; Hevia, Montserrat A.; Wielandt, Ana Maria; De La Fuente, Marjorie; Church, James; Carvallo, Pilar; López Kostner, Francisco (2010)
      PURPOSE: Lynch syndrome is the most common inherited syndrome of colorectal cancer, caused principally by germline mutations in MLH1 and MSH2. We report our experience with genetic screening in the diagnosis of Lynch ...
    • VEGF in the muscular layer of placental blood vessels: Immuno-expression in preeclampsia and intrauterine ... 
      Bosco, C.; Buffet, C.; Matías Díaz, E.; Rodrigo Salinas, Ramón; Morales, P.; Barja, P.; Terra, R.; Parra-Cordero, M. (2010)
      The pathophysiology of preeclampsia (PE), a disorder occurring in 5% of all pregnancies, remains largely unknown, but early placental hypoxia and oxidative stress are known to be involved in the mechanism of the syndrome. ...
    • Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory ... 
      Morales, Paola; Simola, Nicola; Bustamante, Diego; Lisboa, Francisco; Fiedler, Jenny; Gebicke Haerter, Peter J.; Morelli, Micaela; Tasker, R. Andrew; Herrera-Marschitz Muller, Mario (2010)
      There is no established treatment for the long-term effects produced by perinatal asphyxia. Thus, we investigated the neuroprotection provided by nicotinamide against the effects elicited by perinatal asphyxia on hippocampus ...
    • B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, ... 
      Catalán Martina, Diego; Aravena, Octavio; Sabugo, Francisca; Wurmann, Pamela; Soto, Lilian; Kalergis, Alexis M.; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos (2010)
      Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory ...