Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 41001-41020 of 101786

    • Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency 
      Balasubramanian, Ravikumar; Choi, Jin Ho; Francescatto, Ludmila; Willer, Jason; Horton, Edward R.; Asimacopoulos, Eleni P.; Stankovic, Konstantina M.; Plummer, Lacey; Buck, Cassandra L.; Quinton, Richard; Nebesio, Todd D.; Mericq, Verónica; Merino, Paulina M.; Meyer, (National Academy of Sciences, 2014)
      © 2014, National Academy of Sciences. All rights reserved. Inactivating mutations in chromodomain helicase DNA binding protein 7 (CHD7) cause CHARGE syndrome, a severe multiorgan system disorder of which Isolated ...
    • Effect of hydrogen peroxide on the biosynthesis of heme and proteins: Potential implications for the ... 
      Farah, Carolina; Levicán, Gloria; Ibba, Michael; Orellana, Omar (MDPI AG, 2014)
      © 2014 by the authors; licensee MDPI, Basel, Switzerland. Glutamyl-tRNA (Glu-tRNAGlu) is the common substrate for both protein translation and heme biosynthesis via the C5 pathway. Under normal conditions, an adequate ...
    • Obesity and its relation to depressive symptoms and sedentary lifestyle in middle-aged women 
      Blümel, Juan E.; Chedraui, Peter; Aedo Monsalve, Sócrates; Fica, Juan; Mezones Holguín, Edward; Barón, Germán; Bencosme, Ascanio; Benítez, Zully; Bravo, Luz M.; Calle, Andrés; Flores, Daniel; Espinoza, María T.; Gómez, Gustavo; Hernández-Bueno, José A.; Laribezcoa, Fiorella; Mar (Elsevier Ireland Ltd, 2015)
      © 2014 Elsevier Ireland Ltd. All rights reserved.Background The prevalence of obesity increases during female mid-life and although many factors have been identified, data from Latin America is lacking. Objective To assess ...
    • Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy? 
      Roco, ángela; Cayún, Juan; Contreras, Stephania; Stojanova, Jana; Quiñones, Luis (Frontiers Media S.A., 2014)
      © 2014 Roco, Cayún, Contreras, Stojanova and Quiñones.Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the ...
    • Validation of child behavior inventory for children ages 1 1/2 to 5 years (CBCL 1 1/2-5) at the Santiago ... 
      Lecannelier, Felipe; Ewert, J. Carola Pérez; Groissman, Stephanie; Gallardo, Daniela; Bardet, Ana María; Bascuñan, Andrea; Rodríguez, Jorge (Pontificia Universidad Javeriana, 2014)
      Prevalence studies in infant and preschool mental health have been scarce and insufficient. Considering the ample neurobiological, psychological, economical and social evidence that has demonstrated that intervening in ...
    • Geographic variation in acoustic communication in anurans and its neuroethological implications 
      Velásquez, Nelson A. (Elsevier Masson SAS, 2014)
      © 2014 Elsevier Ltd.Geographic variation of traits may represent the first step for evolutionary divergence potentially leading to speciation. Signals are behavioral traits of particular interest for the study of variation ...
    • Alteraciones electrocardiográficas en hipotermia severa accidental. Caso clínico y revisión de la literatura 
      Muñoz Bonilla, Pilar; Rossel Mariángel, Víctor (Sociedad Medica de Santiago, 2014)
      We report a 77-year-old female patient who was admitted to the Emergency Department with impairment of consciousness, hypotension, bradycardia and hypothermia. She required endotracheal intubation and transfer to Intensive ...
    • Aneuploidy in spermatids of Robertsonian (Rb) chromosome heterozygous mice 
      Manieu, Catalina; González, Marisel; López-Fenner, Julio; Page, Jesús; Ayarza, Eliana; Fernández Donoso, Raúl; Berríos, Soledad (Kluwer Academic Publishers, 2014)
      © 2014, The Author(s). Rb translocations are chromosomal rearrangements frequently found in natural populations of the house mouse Mus musculus domesticus. The standard diploid karyotype of the house mouse consisting of ...
    • Bleomycin-induced γH2AX foci map preferentially to replicating domains in CHO9 interphase nuclei 
      Liddle, Pablo; Lafon-Hughes, Laura; Di Tomaso, María Vittoria; Reyes-Ábalos, Ana Laura; Jara, Jorge; Cerda, Mauricio; Härtel, Steffen; Folle, Gustavo A. (Kluwer Academic Publishers, 2014)
      © 2014, Springer Science+Business Media Dordrecht.Exposure to DNA damaging agents triggers phosphorylation of histone variant H2AX (generating γH2AX) in large chromatin regions flanking DNA lesions, allowing their ...
    • Prevalence of congenital malformations at birth in chilean maternity hospitals Prevalencia al nacimiento ... 
      Julio, Nazer H.; Lucía, Cifuentes O. (Sociedad Medica de Santiago, 2014)
      © 2014, Sociedad Medica de Santiago. All rights reserved. Background: The Latin American Collaborative Study of Congenital Malformations (ECLAMC) is an epidemiological surveillance system operating in 11 South American ...
    • Hypnoanalgesia and the study of pain experience: From Cajal to modern neuroscience 
      Lanfranco, Renzo C.; Canales-Johnson, Andre´s; Huepe, David (Frontiers Research Foundation, 2014)
      Santiago Ramo´n y Cajal (1852-1934) did not only contribute to neurobiology and neurohistology. At the end of the 19th century, he published one of the first clinical reports on the employment of hypnotic suggestion to ...
    • Management of ischemic strokes derived from intraventricular thrombi. Report of two cases Accidente ... 
      Oberreuter, Gerardo; Silva, Natalia; Caba, Sheila; Morales, Marcelo; Nieto, Elena; Guevara, Carlos (Sociedad Medica de Santiago, 2014)
      © 2014, Sociedad Medica de Santiago. All rights reserved.The origin of 20% of ischemic strokes is a left ventricular thrombus. We report two patients with strokes originating from cardiac thrombi, treated in two different ...
    • Development and population parameters of cohorts of the chilean recluse spider Loxosceles laeta Desarrollo ... 
      Canals Lambarri, Mauricio; Solís Muñoz, Rigoberto (Sociedad Chilena de Infectologia, 2014)
      © 2014 Sociedad Chilena de Infectologia. All rights reserved.Background: Despite the abundant eco-epidemiological knowledge of the Chilean reclusive spider, Loxosceles laeta, which causes all forms of loxoscelism in Chile, ...
    • Prostate cancer screening is associated with educational level and knowledge about the disease Nivel ... 
      Novoa, Camilo; Anguita, Carolina; Badilla-O, Sebastián; Aliaga, Alfredo; Reyes, Diego (Sociedad Medica de Santiago, 2014)
      © 2014, Sociedad Medica de Santiago. All rights reserved.Background: The screening of prostate cancer allows an earlier diagnosis, allowing more therapeutic options. This screening depends in part on spontaneous patients’ ...
    • Programa colaborativo a distancia para el tratamiento de la enfermedad depresiva 
      Rojas, María Graciela; Castro, Ariel; Guajardo, Viviana; Alvarado, Rubén; Isamit, Cristian; Fritsch, Rosemarie (Sociedad Médica de Santiago, 2014)
      Background: In the treatment of depression, primary care teams play an important role, whose effectiveness improves when inserted into a collaborative model of disease management. Aim: To report the results of a clinical ...
    • Respuesta de los centros de atención primaria en salud mental después del terremoto y tsunami del 2010 en ... 
      Vitriol, Verónica; Minoletti Scaramelli, Alberto; Alvarado Muñoz, Rubén; Sierralta, Paula; Cancino, Alfredo (Sociedad Médica de Santiago, 2014)
      Background: Thirty to 50% of people exposed to a natural disaster suffer psychological problems in the ensuing months. Aim: To characterize the activities in mental health developed by Primary Health Care centers after ...
    • Serum fibroblast growth factor 21 levels are inversely associated with growth rates in infancy 
      Mericq, Verónica; De Luca, Francesco; Hernández, María Isabel; Peña, Verónica; Rossel, Katherine; Garcia, Mirna; Avila, Alejandra; Cavada Chacón, Gabriel; Iñíguez Vila, Germán (S. Karger AG, 2014)
      Background: Fibroblast growth factor 21 (FGF21) is a metabolic and growth regulator.Aim: To investigate the role of FGF21 during growth in infancy.Methods: Blood samples for FGF21, leptin, insulin and glucose were collected ...
    • Etanercept in moderate rheumatoid arthritis: PRESERVE study results from central/eastern Europe, Latin ... 
      Pavelka, Karel; Burgos-Vargas, Ruben; Miranda, Pedro; Guzman, Renato; Yen, Jeng Hsien; Izzi, Mustafa Al; Szekanecz, Zoltan; Tang, Boxiong; Szumski, Annette; Kotak, Sameer; Bananis, Eustratios; Koenig, Andrew S.; Mahgoub, Ehab Y.; Rahman, Mahboob U. (Future Medicine Ltd., 2014)
      © 2014 Future Medicine Ltd.Aims: We compared etanercept 50 mg once weekly (ETN50)/methotrexate versus etanercept 25 mg (ETN25)/methotrexate or biologic-free methotrexate after response to ETN50/methotrexate in moderate ...
    • Anatomy of reproductive tract in octodon degus molina: A nonscrotal rodent 
      Contreras, L.; Bustos-Obregôn, E. (Informa Healthcare, 1980)
      O. degusreproductive tract is characterized externally by a perianal circle with the penis pointing posteriorly. Beneath the perianal circle is the cremasteric sac. Testes are always inside the abdomen, with the epididymis ...
    • Characterization of azole resistance mechanisms in chilean clinical isolates of Candida albicans Caracterización ... 
      Fuentes, Marisol; Hermosilla, Germán; Alburquenque, Claudio; Falconer, Mary A.; Amaro, José; Tapia, Cecilia (Sociedad Chilena de Infectologia, 2014)
      © 2014 Sociedad Chilena de Infectologia. All rights reserved. Abstract Introduction: The commensal yeast Candida albicans, can cause superficial or systemic candidiasis in susceptible hosts. In Chile, azole antifungals are ...