Repositorio Académico de la Universidad de Chile: Recent submissions

Now showing items 41101-41120 of 101786

    • Use of internet for mental health programs aimed at adolescents Prevención, detección, tratamiento o ... 
      Hoffmann, Marianela; Rojas, Graciela; Martínez, Vania (Sociedad Medica de Santiago, 2014)
      Background: The widespread use of INTERNET by adolescents, renders it a simple and accessible means for health care campaigns Aim: To perform a systematic review of ISI publications about INTERNET use for adolescent mental ...
    • Engram formation in psychiatric disorders 
      Gebicke-Haerter, Peter J. (Frontiers Research Foundation, 2014)
      Environmental factors substantially influence beginning and progression of mental illness, reinforcing or reducing the consequences of genetic vulnerability. Often initiated by early traumatic events, "engrams" or memories ...
    • Characterization of episodes of febrile neutropenia in children with acute myeloid leukemia and acute ... 
      Ducasse, Karen; Fernández, José P.; Salgado, Carmen; Álvarez, Ana M.; Avilés, Carmen L.; Becker, Ana; Topelberg, Santiago; Tordecilla, Juan; Varas, Mónica; Villarroel, Milena; Viviani, Tamara; Zubieta, Marcela; Santolaya de Pablo, María Elena (Sociedad Chilena de Infectologia, 2014)
      Introduction: Leukemia is the most common cancer in Chilean children. Acute lymphoblastic leukemia (ALL) is more prevalent and longer survival compared to acute myeloid leukemia (AML). Aims: To describe episodes of febrile ...
    • Ovarian morphometry and mRNA expression of antimullerian hormone (AMH), follicle stimulating hormone receptor ... 
      Rojas García, Pedro; Recabarren, M. P.; Palma, S.; Maliqueo Yevilao, Manuel; Carrasco, A.; Sir Petermann, Teresa; Recabarren, S. E. (Universidad Austral de Chile, 2014)
      Antenatal exposure to testosterone (T) has a series of consequences on postnatal reproductive parameters in females of several animal species. In sheep born under this condition the ovaries are characterized by an increased ...
    • Programming of fetal insulin resistance in pregnancies with maternal obesity by ER stress and inflammation 
      Westermeier, Francisco; Sáez, Pablo J.; Villalobos-Labra, Roberto; Sobrevia, Luis; Farías-Jofré, Marcelo (Hindawi Publishing Corporation, 2014)
      The global epidemics of obesity during pregnancy and excessive gestational weight gain (GWG) are major public health problems worldwide. Obesity and excessive GWG are related to several maternal and fetal complications, ...
    • Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance 
      Troncoso, Rodrigo; Paredes, Felipe; Parra, Valentina; Gatica, Damián; Vásquez Trincado, César Alonso; Quiroga, Clara; Bravo Sagua, Roberto; López Crisosto, Camila; Rodriguez, Andrea E.; Oyarzún, Alejandra P.; Kroemer, Guido; Lavandero González, Sergio (Taylor and Francis Inc., 2014)
      Glucocorticoids, such as dexamethasone, enhance protein breakdown via ubiquitin-proteasome system. However, the role of autophagy in organelle and protein turnover in the glucocorticoid-dependent atrophy program remains ...
    • The placental pursuit for an adequate oxidant balance between the mother and the fetus 
      Herrera, Emilio A.; Krause, Bernardo; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Casanello, Paola; Parra Cordero, Mauro; Llanos Mansilla, Jorge (Frontiers Research Foundation, 2014)
      The placenta is the exchange organ that regulates metabolic processes between the mother and her developing fetus. The adequate function of this organ is clearly vital for a physiologic gestational process and a healthy ...
    • Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa 
      Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P.; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V.; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M.; (Wiley-Liss Inc., 2014)
      Knockout models have shown that the coagulation system has a role in vascular development and angiogenesis. Herein, we report for the first time that zymogen FX and its active form (FXa) possess anti-angiogenic properties. ...
    • Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates ... 
      Elisa Kallio, K. A.; Marchesani, Marja; Vlachopoulou, Efthymia; Mäntylä, Päivi; Paju, Susanna; Buhlin, Kåre; Suominen, Anna L.; Contreras, Johanna; Knuuttila, Matti; Hernandez, Marcela; Huumonen, Sisko; Nieminen, Markku S.; Perola, Markus; Sinisalo, Juha; Lokki, Marja (American Society for Microbiology, 2014)
      Periodontitis is a chronic inflammatory disease with a multifactorial etiology. We investigated whether human major histocompatibility complex (MHC) polymorphisms (6p21.3) are associated with periodontal parameters. Parogene ...
    • Aerosol effects on the UV irradiance in Santiago de Chile 
      Cordero, R. R.; Seckmeyer, G.; Damiani, A.; Jorquera, J.; Carrasco, J.; Muñoz, R.; Da Silva, L.; Labbe, F.; Laroze, D. (Elsevier Ltd, 2014)
      Santiago de Chile (33°27' S-70°41' W) is a mid-latitude city of 6 million inhabitants with a complicated surrounding topography. Aerosol extinction in Santiago is determined by the semi-arid local climate, the urban ...
    • Diet of phytotoma rutila (Passeriformes: Cotingidae) in the central Monte desert, Argentina Dieta de phytotoma ... 
      Ríos, Juan Manuel; Zarco, Agustín; Mosca Torres, María E.; Sabat Kirkwood, Alejandro Pablo (Universidad de Concepcion, 2014)
      Botanical composition of the diet of White-tipped Plantcutter Phytotoma rutila in the central Monte desert from Argentina, was determined by microhistological analysis of excreta. In both sexes, the diet was composed by a ...
    • Scleromyxedema without paraproteinemia 
      Abarzúa, Alvaro A.; Giesen, Laura F.; Sandoval, Mauricio O.; González, Sergio B. (Blackwell Publishing Ltd, 2014)
      Background: Scleromyxedema is a rare generalized form of lichen myxedematosus, a chronic cutaneous mucinosis of unknown etiology usually associated with a monoclonal gammopathy and underlying systemic disorders. It is ...
    • A structural view of ligand-dependent activation in thermoTRP channels 
      Steinberg, Ximena; Lespay-Rebolledo, Carolyne; Brauchi, Sebastian (Frontiers Research Foundation, 2014)
      Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped into seven sub-families. Although great advances have been made regarding the activation and modulation of TRP channel activity, ...
    • Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells 
      Li, Q.; Zhu, X.; Ishikura, S.; Zhang, D.; Gao, J.; Sun, Y.; Contreras Ferrat, Ariel Eduardo; Foley, K. P.; Lavandero González, Sergio; Yao, Z.; Bilan, Philip J.; Klip, Amira; Niu, W. (American Physiological Society, 2014)
      Elevating cytosolic Ca2+ stimulates glucose uptake in skeletal muscle, but how Ca2+ affects intracellular traffic of GLUT4 is unknown. In tissue, changes in Ca2++ leading to contraction preclude analysis of the impact of ...
    • Southern annular mode-like changes in southwestern Patagonia at centennial timescales over the last three millennia 
      Moreno Moncada, Patricio; Vilanova, I.; Villa Martínez, Rodrigo; Garreaud Salazar, René; Rojas, M.; De Pol-Holz, Ricardo (Nature Publishing Group, 2014)
      Late twentieth-century instrumental records reveal a persistent southward shift of the Southern Westerly Winds during austral summer and autumn associated with a positive trend of the Southern Annular Mode (SAM) and ...
    • Copy number variants in patients with short stature 
      Van Duyvenvoorde, Hermine A.; Lui, Julian C.; Kant, Sarina G.; Oostdijk, Wilma; Gijsbers, Antoinet C.J.; Hoffer, Mariëtte J.V.; Karperien, Marcel; Walenkamp, Marie J.E.; Noordam, Cees; Voorhoeve, Paul G.; Mericq, Verónica; Pereira, Alberto M.; Claahsen-Van De Grinten (Nature Publishing Group, 2014)
      Height is a highly heritable and classic polygenic trait. Recent genome-wide association studies (GWAS) have revealed that at least 180 genetic variants influence adult height. However, these variants explain only about ...
    • A performance/cost evaluation for a GPU-based drug discovery application on volunteer computing 
      Guerrero, Ginés D.; Imbernón, Baldomero; Pérez-Sánchez, Horacio; Sanz, Francisco; García, José M.; Cecilia, José M. (Hindawi Publishing Corporation, 2014)
      Bioinformatics is an interdisciplinary research field that develops tools for the analysis of large biological databases, and, thus, the use of high performance computing (HPC) platforms is mandatory for the generation of ...
    • Association between genetic polymorphisms of interleukin 6 (IL6), IL6R and IL18 with metabolic syndrome in ... 
      Suazo, José; Smalley, Susan Valerie; Hodgson, María Isabel; Weisstaub, Gerardo; González, Andrea; Santos, José Luis (Sociedad Medica de Santiago, 2014)
      Background: Metabolic Syndrome (MS) is highly prevalent among obese children and adolescents and is considered a predictor for the development of type 2 diabetes mellitus and cardiovascular disease. Obesity is associated ...
    • Gene geography of Chile. Regional distribution of American, European and African genetic contributions ... 
      Fuentes, Macarena; Pulgar, Iván; Gallo, Carla; Bortolini, María Cátira; Canizales-Quinteros, Samuel; Bedoya, Gabriel; González-José, Rolando; Ruiz-Linares, Andrés; Rothhammer Engel, Francisco (Sociedad Medica de Santiago, 2014)
      Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
    • Impact beyond the objectives: A qualitative study of a faculty development program in medical education ... 
      Moore, Philippa; Montero, Luz; Triviño, Ximena; Sirhan, Marisol; Leiva, Loreto (Sociedad Medica de Santiago, 2014)
      Background: In medical education there has been increasing emphasis on faculty development programs aimed at the professionalization of teaching and increasing students' learning. However, these programs have been shown ...